Filters (5)
Download Results
24 research outcomes, page 1 of 3
  • publication . Article . 2018
    Open Access English
    Authors:
    Conrad V. Simoben; Dina Robaa; Alokta Chakrabarti; Karin Schmidtkunz; Martin Marek; Julien Lancelot; Srinivasaraghavan Kannan; Jelena Melesina; Tajith B. Shaik; Raymond J. Pierce; ...
    Persistent Identifiers
    Publisher: MDPI
    Project: EC | SETTREND (241865), EC | A-PARADDISE (602080)

    International audience; A promising means in the search of new small molecules for the treatment of schistosomiasis (amongst other parasitic ailments) is by targeting the parasitic epigenome. In the present study, a docking based virtual screening procedure using the cr...

    Add to ORCIDorcid
  • publication . Article . 2015
    Open Access English
    Authors:
    Afonso M.S. Duarte; Fotis Psomopoulos; Christophe Blanchet; Alexandre M. J. J. Bonvin; Manuel Corpas; Alain Franc; Rafael C. Jimenez; Jesús Marco de Lucas; Tommi Nyrönen; Gergely Sipos; ...
    Project: FCT | SFRH/BPD/78075/2011 (SFRH/BPD/78075/2011), EC | BIOMEDBRIDGES (284209), WT , AKA | ELIXIR - Data for Life Eu... (273655), FCT | EXPL/BBB-BEP/1356/2013 (134381), EC | WENMR (261572), EC | EGI-INSPIRE (261323)

    This is an open-access article.-- et al.

    Add to ORCIDorcid
  • publication . Article . 2018
    Open Access English
    Authors:
    Assaf Gal; Andrea Sorrentino; Keren Kahil; Eva Pereiro; Damien Faivre; André Scheffel;
    Publisher: HAL CCSD
    Project: EC | BIOSTRUCT-X (283570)

    Calcium storage organelles are common to all eukaryotic organisms and play a pivotal role in calcium signaling and cellular calcium homeostasis. In most organelles, the intraorganellar calcium concentrations rarely exceed micromolar levels. Acidic organelles called acid...

    Add to ORCIDorcid
  • publication . Article . 2020
    Open Access English
    Authors:
    Marc-André Hograindleur; Gregory Effantin; Daphna Fenel; Caroline Mas; André Lieber; Guy Schoehn; Pascal Fender; Emilie Vassal-Stermann;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), ANR | Ad-Cadh (ANR-18-CE11-0001)

    International audience; The study of viruses causing acute respiratory distress syndromes (ARDS) is more essential than ever at a time when a virus can create a global pandemic in a matter of weeks. Among human adenoviruses, adenovirus of serotype 7 (HAdV7) is one of th...

    Add to ORCIDorcid
  • publication . Article . 2016
    Open Access
    Authors:
    Ison, Jon; Rapacki, Kristoffer; Ménager, Hervé; Kalaš, Matúš; Rydza, Emil; Chmura, Piotr; Anthon, Christian; Beard, Niall; Berka, Karel; Bolser, Dan; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: NIH | Gene Ontology Consortium (5U41HG002273-14), EC | ELIXIR-EXCELERATE (676559), EC | BIOMEDBRIDGES (284209)

    International audience; Life sciences are yielding huge data sets that underpin scientific discoveries fundamental to improvement in human health, agriculture and the environment. In support of these discoveries, a plethora of databases and tools are deployed, in techni...

    Add to ORCIDorcid
  • publication . Article . Other literature type . 2015
    Open Access
    Authors:
    Carmela Garcia-Doval; José R. Castón; Daniel Luque; Meritxell Granell; José M. Otero; Antonio L. Llamas-Saiz; Madalena Renouard; Pascale Boulanger; Mark J. van Raaij;
    Publisher: MDPI
    Project: EC | BIOSTRUCT-X (283570)

    This research was sponsored by grants BFU2011-24843, BIO2011-14756-E, BFU2014-53425P (Mark J. van Raaij), and BFU2014-55475R (José R. Castón) and the BioFiViNet network (FIS2011-16090-E) from the Spanish Ministry of Economy and Competitiveness, grant S2013/MIT-2807 (Jos...

    Add to ORCIDorcid
  • publication . Article . Preprint . 2021
    Open Access
    Authors:
    Christophe Caillat; Delphine Guilligay; Johana Torralba; Nikolas Friedrich; Jose L Nieva; Alexandra Trkola; Christophe J Chipot; François L Dehez; Winfried Weissenhorn;
    Persistent Identifiers
    Publisher: eLife Sciences Publications, Ltd
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | EAVI2020 (681137)

    The HIV-1 gp120/gp41 trimer undergoes a series of conformational changes in order to catalyze gp41-induced fusion of viral and cellular membranes. Here, we present the crystal structure of gp41 locked in a fusion intermediate state by an MPER-specific neutralizing antib...

    Add to ORCIDorcid
  • publication . Article . 2019
    Restricted English
    Authors:
    A. Jimenez; Slavica Jonic; Tomáš Majtner; Joaquín Otón; José Luis Vilas; David Maluenda; Javier Mota; Erney Ramírez-Aportela; Marta Martínez; Y. Rancel; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: EC | INSTRUCT-ULTRA (731005), EC | iNEXT (653706), EC | ELIXIR-EXCELERATE (676559)

    This work was supported by the Spanish Ministry of Economy and Competitiveness through Grants BIO2016-76400-R(AEI/FEDER, UE), Comunidad Autonoma de Madrid through Grant: S2017/BMD-3817, Instituto de Salud Carlos III, PT13/0001/0009, PT17/0009/0010 and European Union (EU...

    Add to ORCIDorcid
  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Carlos Oscar S. Sorzano; A. Jimenez; Javier Mota; José Luis Vilas; David Maluenda; María Jesús Martínez; Erney Ramírez-Aportela; Tomáš Majtner; Joan Segura; Rubén J. Sánchez-García; ...
    Persistent Identifiers
    Publisher: International Union of Crystallography
    Project: EC | iNEXT (653706), EC | ELIXIR-EXCELERATE (676559), EC | West-Life (675858), EC | EOSCpilot (739563), EC | CORBEL (654248)

    Single-particle analysis by electron microscopy is a well established technique for analyzing the three-dimensional structures of biological macromolecules. Besides its ability to produce high-resolution structures, it also provides insights into the dynamic behavior of...

    Add to ORCIDorcid
  • publication . Preprint . Article . Other literature type . 2019
    Open Access English
    Authors:
    Nada Essawy; Camille Samson; Ambre Petitalot; Sophie Moog; Anne Bigot; Isaline Herrada; Agathe Marcelot; Ana-Andrea Arteni; Catherine Coirault; Sophie Zinn-Justin;
    Persistent Identifiers
    Publisher: Preprints
    Project: EC | iNEXT (653706)

    Emerin is a nuclear envelope protein that contributes to genome organization and cell mechanics. Through its N-terminal LAP2-emerin-MAN1 (LEM)-domain, emerin interacts with the DNA-binding protein barrier-to-autointegration (BAF). Emerin also binds to members of the lin...

    Add to ORCIDorcid
24 research outcomes, page 1 of 3