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45 research outcomes, page 1 of 5
  • publication . Article . 2015
    Open Access English
    Authors:
    Stéphanie Thébault; Morgane Agez; Xiaoke Chi; Johann Stojko; Vincent Cura; Stephanie B. Telerman; Laurent Maillet; Fabien Gautier; Isabelle Billas-Massobrio; Catherine Birck; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | INRT (ANR-10-LABX-0030), CIHR , ANR | UNISTRA (ANR-10-IDEX-0002)

    International audience; Translationally Controlled Tumor Protein (TCTP) is anti-apoptotic, key in development and cancer, however without the typical Bcl2 family members' structure. Here we report that TCTP contains a BH3-like domain and forms heterocomplexes with Bcl-x...

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  • publication . Article . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Raphaël de Wijn; Rollet; Engilberge; McEwen; Hennig; Betat; Moerl; Riobe; Maury; Girard; ...
    Publisher: HAL CCSD
    Project: ANR | UNISTRA (ANR-10-IDEX-0002), ANR | Ln23 (ANR-13-BS07-0007)

    ABSTRACTThe reproducible preparation of well diffracting crystals is a prerequisite for every structural study based on crystallography. An instrument called the XtalController has recently been designed that allows the monitoring of crystallization assays using dynamic...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Ison, J.; Rapacki, K.; Mé nager, H.; Kalaš , M.; Rydza, E.; Chmura, P.; Anthon, C.; Beard, N.; ...
    Project: EC | ELIXIR-EXCELERATE (676559), EC | BIOMEDBRIDGES (284209), NIH | Gene Ontology Consortium (5U41HG002273-14)

    Life sciences are yielding huge data sets that underpin scientific discoveries fundamental to improvement in human health, agriculture and the environment. In support of these discoveries, a plethora of databases and tools are deployed, in technically complex and divers...

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  • publication . Other literature type . Article . 2019
    Open Access English
    Authors:
    Ambroise Desfosses; Sigrid Milles; Malene Ringkjøbing Jensen; Serafima Guseva; Jacques-Philippe Colletier; Damien Maurin; Guy Schoehn; Irina Gutsche; Rob W.H. Ruigrok; Martin Blackledge;
    Persistent Identifiers
    Publisher: National Academy of Sciences
    Project: EC | EMBOCOFUND2012 (600394)

    International audience; Assembly of paramyxoviral nucleocapsids on the RNA genome is an essential step in the viral cycle. The structural basis of this process has remained obscure due to the inability to control encapsidation. We used a recently developed approach to a...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Conrad V. Simoben; Dina Robaa; Alokta Chakrabarti; Karin Schmidtkunz; Martin Marek; Julien Lancelot; Srinivasaraghavan Kannan; Jelena Melesina; Tajith B. Shaik; Raymond J. Pierce; ...
    Persistent Identifiers
    Publisher: MDPI AG
    Project: EC | A-PARADDISE (602080), EC | SETTREND (241865)

    International audience; A promising means in the search of new small molecules for the treatment of schistosomiasis (amongst other parasitic ailments) is by targeting the parasitic epigenome. In the present study, a docking based virtual screening procedure using the cr...

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  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    Maysam Mansouri; Itxaso Bellon-Echeverria; Aurélien Rizk; Zahra Ehsaei; Chiara Cianciolo Cosentino; Catarina S. Silva; Ye Xie; Frederick M. Boyce; M. Wayne Davis; Stephan C.F. Neuhauss; ...
    Publisher: Springer Science and Business Media LLC
    Project: EC | BIOSTRUCT-X (283570), EC | COMPLEXINC (279039), SNSF | Decision making in the en... (31003A-118351), SNSF | Structural and functional... (31003A_152908), EC | SYNSIGNAL (613879), SNSF | Structure/function analys... (31003A_130463)

    Multigene delivery and subsequent cellular expression is emerging as a key technology required in diverse research fields including, synthetic and structural biology, cellular reprogramming and functional pharmaceutical screening. Current viral delivery systems such as ...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Dmitry Bratanov; Taras Balandin; Ekaterina Round; Vitaly Shevchenko; Ivan Gushchin; Vitaly Polovinkin; Valentin Borshchevskiy; Valentin Gordeliy;
    Publisher: PLoS
    Project: EC | EDICT (201924)

    Published by PLoS, Lawrence

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  • publication . Article . 2017
    Open Access English
    Authors:
    J. Retel; Andrew J. Nieuwkoop; Matthias Hiller; Victoria A. Higman; Emeline Barbet-Massin; Jan Stanek; Loren B. Andreas; W. Trent Franks; Barth-Jan van Rossum; Kutti R. Vinothkumar; ...
    Project: EC | iNEXT (653706), EC | BIO-NMR (261863)

    β-barrel proteins mediate nutrient uptake in bacteria and serve vital functions in cell signaling and adhesion. For the 14-strand outer membrane protein G of Escherichia coli, opening and closing is pH-dependent. Different roles of the extracellular loops in this proces...

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  • publication . Article . 2015 . Embargo End Date: 16 Jan 2018
    Open Access
    Authors:
    Huaying Zhao; Rodolfo Ghirlando; Carlos Alfonso; Fumio Arisaka; Ilan Attali; David L. Bain; Marina Bakhtina; Donald F. Becker; Gregory J. Bedwell; Ahmet Bekdemir; ...
    Publisher: Apollo - University of Cambridge Repository
    Project: NIH | Mechanisms for Histone H2... (5R01GM095822-08), NIH | MOLECULAR INTERACTION IN ... (2R01GM029158-19), NIH | SPECIFICITY OF INTERCALAT... (5R01CA035635-13), NIH | Structure and Relations o... (5R01GM015792-39), NIH | The chaperone function of... (5F31GM105363-02), NIH | REGULATION OF UBIQUITINAT... (5R01GM109102-04), NIH | Bacterial Expression Core (5P50GM082545-02), NIH | COBRE on Membrane Protein... (5P30GM103519-04), NIH | Structure and Function of... (3R01GM067777-07S1)

    Peer reviewed

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  • publication . Article . 2017
    Open Access English
    Authors:
    Jonathan Pansieri; Marie Plissonneau; Nathalie Martine Stransky-Heilkron; Mireille Dumoulin; Laurence Heinrich-Balard; Pascaline Rivory; Jean-François Morfin; Éva Tóth; Maria João Saraiva; Eric Allémann; ...
    Persistent Identifiers
    Project: EC | EURONANOMED (234811)

    International audience; Gadolinium-based nanoparticles were functionalized with either the Pittsburgh compound B or a nanobody (B10AP) in order to create multimodal tools for an early diagnosis of amyloidoses.MATERIALS & METHODS:The ability of the functionalized nanopar...

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45 research outcomes, page 1 of 5