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35 research outcomes, page 1 of 4
  • publication . Article . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Raphaël de Wijn; Rollet; Engilberge; McEwen; Hennig; Betat; Moerl; Riobe; Maury; Girard; ...
    Publisher: HAL CCSD
    Project: ANR | UNISTRA (ANR-10-IDEX-0002), ANR | Ln23 (ANR-13-BS07-0007)

    ABSTRACTThe reproducible preparation of well diffracting crystals is a prerequisite for every structural study based on crystallography. An instrument called the XtalController has recently been designed that allows the monitoring of crystallization assays using dynamic...

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  • publication . Other literature type . Article . 2019
    Open Access English
    Authors:
    Ambroise Desfosses; Sigrid Milles; Malene Ringkjøbing Jensen; Serafima Guseva; Jacques-Philippe Colletier; Damien Maurin; Guy Schoehn; Irina Gutsche; Rob W.H. Ruigrok; Martin Blackledge;
    Persistent Identifiers
    Publisher: National Academy of Sciences
    Project: EC | EMBOCOFUND2012 (600394)

    International audience; Assembly of paramyxoviral nucleocapsids on the RNA genome is an essential step in the viral cycle. The structural basis of this process has remained obscure due to the inability to control encapsidation. We used a recently developed approach to a...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Conrad V. Simoben; Dina Robaa; Alokta Chakrabarti; Karin Schmidtkunz; Martin Marek; Julien Lancelot; Srinivasaraghavan Kannan; Jelena Melesina; Tajith B. Shaik; Raymond J. Pierce; ...
    Persistent Identifiers
    Publisher: MDPI AG
    Project: EC | A-PARADDISE (602080), EC | SETTREND (241865)

    International audience; A promising means in the search of new small molecules for the treatment of schistosomiasis (amongst other parasitic ailments) is by targeting the parasitic epigenome. In the present study, a docking based virtual screening procedure using the cr...

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  • publication . Article . 2017
    Open Access English
    Authors:
    J. Retel; Andrew J. Nieuwkoop; Matthias Hiller; Victoria A. Higman; Emeline Barbet-Massin; Jan Stanek; Loren B. Andreas; W. Trent Franks; Barth-Jan van Rossum; Kutti R. Vinothkumar; ...
    Project: EC | iNEXT (653706), EC | BIO-NMR (261863)

    β-barrel proteins mediate nutrient uptake in bacteria and serve vital functions in cell signaling and adhesion. For the 14-strand outer membrane protein G of Escherichia coli, opening and closing is pH-dependent. Different roles of the extracellular loops in this proces...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Jonathan Pansieri; Marie Plissonneau; Nathalie Martine Stransky-Heilkron; Mireille Dumoulin; Laurence Heinrich-Balard; Pascaline Rivory; Jean-François Morfin; Éva Tóth; Maria João Saraiva; Eric Allémann; ...
    Persistent Identifiers
    Project: EC | EURONANOMED (234811)

    International audience; Gadolinium-based nanoparticles were functionalized with either the Pittsburgh compound B or a nanobody (B10AP) in order to create multimodal tools for an early diagnosis of amyloidoses.MATERIALS & METHODS:The ability of the functionalized nanopar...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Yoann Millerioux; Muriel Mazet; Guillaume Bouyssou; Stefan Allmann; Tiila Riikka Kiema; Eloïse Bertiaux; Laetitia Fouillen; Chandan J. Thapa; Marc Biran; Nicolas Plazolles; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | PARAMET (290080), ANR | ParaFrap (ANR-11-LABX-0024), ANR | GLYCONOV (ANR-15-CE15-0025)

    Author summary In this study, we have (i) determined the carbon sources used by the Trypanosoma brucei procyclic insect form to feed the essential lipid biosynthetic pathways, (ii) further characterized the metabolic pathways leading to their degradation into acetyl-CoA...

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  • publication . Article . 2017
    Open Access English
    Authors:
    F.R. Ehrmann; Johann Stojko; Alexander Metz; François Debaene; Luzi Jakob Barandun; Andreas Heine; François Diederich; Sarah Cianférani; Klaus Reuter; Gerhard Klebe;
    Publisher: HAL CCSD
    Project: EC | BIOSTRUCT-X (283570)

    PLoS ONE, 12 (4)

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  • publication . Article . 2018
    Open Access English
    Authors:
    Assaf Gal; Andrea Sorrentino; Keren Kahil; Eva Pereiro; Damien Faivre; André Scheffel;
    Publisher: HAL CCSD
    Project: EC | BIOSTRUCT-X (283570)

    Calcium storage organelles are common to all eukaryotic organisms and play a pivotal role in calcium signaling and cellular calcium homeostasis. In most organelles, the intraorganellar calcium concentrations rarely exceed micromolar levels. Acidic organelles called acid...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Marc-André Hograindleur; Gregory Effantin; Daphna Fenel; Caroline Mas; André Lieber; Guy Schoehn; Pascal Fender; Emilie Vassal-Stermann;
    Persistent Identifiers
    Publisher: MDPI
    Project: ANR | Ad-Cadh (ANR-18-CE11-0001), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    The study of viruses causing acute respiratory distress syndromes (ARDS) is more essential than ever at a time when a virus can create a global pandemic in a matter of weeks. Among human adenoviruses, adenovirus of serotype 7 (HAdV7) is one of the most virulent serotype...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Serena Flori; Pierre-Henri Jouneau; Benjamin Bailleul; Benoit Gallet; Leandro F. Estrozi; Christine Moriscot; Olivier Bastien; Simona Eicke; Alexander F. Schober; Carolina Río Bártulos; ...
    Publisher: HAL CCSD
    Project: EC | ACCLIPHOT (316427)

    Nature Communications, 8

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35 research outcomes, page 1 of 4