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57 research outcomes, page 1 of 6
  • publication . Article . 2017
    Open Access English
    Authors:
    Zagganas, Konstantinos; Vergoulis, Thanasis; Paraskevopoulou, Maria D.; Vlachos, Ioannis S.; Skiadopoulos, Spiros; Dalamagas, Theodore;
    Persistent Identifiers
    Publisher: BioMed Central
    Project: EC | ELIXIR-EXCELERATE (676559)

    Abstract Background A group of miRNAs can regulate a biological process by targeting genes involved in the process. The unbiased miRNA functional enrichment analysis is the most precise in silico approach to predict the biological processes that may be regulated by a gi...

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  • publication . Article . 2009
    Open Access
    Authors:
    Giorgos L. Papadopoulos; Panagiotis Alexiou; Manolis Maragkakis; Martin Reczko; Artemis G. Hatzigeorgiou;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Summary: DIANA-mirPath is a web-based computational tool developed to identify molecular pathways potentially altered by the expression of single or multiple microRNAs. The software performs an enrichment analysis of multiple microRNA target genes comparing each set of ...

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  • publication . Article . 2016
    Restricted
    Authors:
    Vasiliki D. Kostiou; Margarita C. Theodoropoulou; Stavros J. Hamodrakas;
    Persistent Identifiers
    Publisher: Elsevier BV

    Heterotrimeric G-proteins form a major protein family, which participates in signal transduction. They are composed of three subunits, Gα, Gβ and Gγ. The Gα subunit is further divided in four distinct families Gs, Gi/o, Gq/11 and G12/13. The goal of this work was to det...

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  • publication . Article . 2009
    Open Access
    Authors:
    Panagiotis Alexiou; Thanasis Vergoulis; Martin Gleditzsch; George Prekas; Theodore Dalamagas; Molly Megraw; Ivo Grosse; Timos Sellis; Artemis G. Hatzigeorgiou;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    MicroRNAs are small, non-protein coding RNA molecules known to regulate the expression of genes by binding to the 3 0 UTR region of mRNAs. MicroRNAs are produced from longer transcripts which can code for more than one mature miRNAs. miRGen 2.0 is a database that aims t...

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  • publication . Article . 2014
    Open Access
    Authors:
    N. Papanikolaou; G. A. Pavlopoulos; E. Pafilis; T. Theodosiou; R. Schneider; V. P. Satagopam; C. A. Ouzounis; A. G. Eliopoulos; V. J. Promponas; I. Iliopoulos;
    Publisher: Oxford University Press (OUP)

    The iterative process of finding relevant information in biomedical literature and performing bioinformatics analyses might result in an endless loop for an inexperienced user, considering the exponential growth of scientific corpora and the plethora of tools designed t...

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  • publication . Article . 2011
    Open Access
    Authors:
    Chatziioannou, Aristotelis A.; Moulos, Panagiotis;
    Persistent Identifiers
    Publisher: Frontiers Media SA

    StRAnGER is a web application for the automated statistical analysis of annotated gene profiling experiments, exploiting controlled biological vocabularies, like the Gene Ontology or the KEGG pathways terms. Starting from annotated lists of differentially expressed gene...

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  • publication . Article . Other literature type . 2015
    Open Access
    Authors:
    Wolfgang Huber; Vincent J. Carey; Robert Gentleman; Simon Anders; Marc R. J. Carlson; Benilton S. Carvalho; Héctor Corrada Bravo; Sean Davis; Laurent Gatto; Thomas Girke; ...
    Persistent Identifiers

    Bioconductor is an open-source, open-development software project for the analysis and comprehension of high-throughput data in genomics and molecular biology. The project aims to enable interdisciplinary research, collaboration and rapid development of scientific softw...

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  • publication . Article . 2014
    Open Access
    Authors:
    Panagiotis Moulos; Pantelis Hatzis;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    RNA-Seq is gradually becoming the standard tool for transcriptomic expression studies in biological research. Although considerable progress has been recorded in the development of statistical algorithms for the detection of differentially expressed genes using RNA-Seq ...

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  • publication . Article . 2016
    Open Access
    Authors:
    Kleanthi Lakiotaki; Evgenia Kartsaki; Alexandros Kanterakis; Theodora Katsila; George P. Patrinos; George Potamias;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: EC | RD-CONNECT (305444), WT

    One of the challenges that arise from the advent of personal genomics services is to efficiently couple individual data with state of the art Pharmacogenomics (PGx) knowledge. Existing services are limited to either providing static views of PGx variants or applying a s...

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  • publication . Article . 2008
    Authors:
    Bagos, P.G.; Tsirigos, K.D.; Plessas, S.K.; Liakopoulos, T.D.; Hamodrakas, S.J.;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
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57 research outcomes, page 1 of 6