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56,262 research outcomes, page 1 of 5,627
  • publication . Article . 2015
    Open Access
    Authors:
    Noemi del-Toro; Margaret Duesbury; Bianca Habermann; Henning Hermjakob; Manor Askenazi; Sandra Orchard; Rafael C Jimenez;
    Publisher: Oxford University Press (OUP)
    Project: EC | AFFINOMICS (241481), EC | PSIMEX (223411), WT

    The evidence that two molecules interact in a living cell is often inferred from multiple different experiments. Experimental data is captured in multiple repositories, but there is no simple way to assess the evidence of an interaction occurring in a cellular environme...

  • publication . Article . 2012
    Open Access English
    Authors:
    Alice Reid;
    Publisher: Cambridge University Press
    Project: WT

    <jats:title>Abstract</jats:title><jats:p>After the passing of the 1902 Midwives Act, a growing proportion of women were delivered by trained and supervised midwives. Standards of midwifery should therefore have improved over the first three decades of the twentieth cent...

  • publication . Article . 2012
    Open Access English
    Authors:
    Carol Propper; Debbie Lawlor; George Davey Smith; Frank Windmeijer;
    Publisher: Elsevier B.V.
    Project: RCUK | Centre for molecular-base... (G0600705), WT , EC | DEVHEALTH (269874), RCUK | Infering Epidemiological ... (G0601625)

    Highlights ► We examine the effect of adolescent adiposity on educational outcomes. ► We compare the findings using different approaches used in the literature. ► We use an individual fixed effects as well as IV approach, with different sets of instruments. ► We conclud...

  • publication . Preprint . 2017
    Open Access English
    Authors:
    Sarah Teichmann; Fabian Theis; Zhichao Miao; Maren Büttner;
    Publisher: Cold Spring Harbor Laboratory
    Project: WT | Genetic analysis of high ... (069065)

    <jats:title>Abstract</jats:title><jats:p>Single-cell transcriptomics is a versatile tool for exploring heterogeneous cell populations. As with all genomics experiments, batch effects can hamper data integration and interpretation. The success of batch effect correction ...

  • publication . Article . 2014
    Open Access
    Authors:
    Helen Weavers;
    Publisher: Elsevier BV
    Project: WT | Genetic analysis of tubul... (082729), WT | Developmental Biology (083350), WT , WT | Analysis of conserved pat... (094879)

    The normal development of an organ depends on the coordinated regulation of multiple cell activities. Focusing on tubulogenesis, we review the role of specialised cells or groups of cells that are selected from within tissue primordia and differentiate at the outgrowing...

  • publication . Preprint . Other literature type . 2019
    Open Access English
    Authors:
    Neil J. Gemmell; Kim Rutherford; Stefan Prost; Marc Tollis; David Winter; J. Robert Macey; David L. Adelson; Alexander Suh; Terry Bertozzi; José H. Grau; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: WT | ENSEMBL (108749)

    <jats:p>The tuatara (<jats:italic>Sphenodon punctatus</jats:italic>), the only living member of the archaic reptilian order Rhynchocephalia (Sphenodontia) once widespread across Gondwana, is an iconic and enigmatic terrestrial vertebrate endemic to New Zealand. A key li...

  • publication . Review . Article . Other literature type . 2012
    Open Access English
    Authors:
    Jeremy Nicholson; James Kinross; Wei Jia; Elaine Holmes;
    Publisher: AMER ASSOC ADVANCEMENT SCIENCE
    Project: EC | TORNADO (222720), NIH | Aldehydes in Alcohol-Indu... (5R01AA020212-05), WT

    International audience; The composition and activity of the gut microbiota codevelop with the host from birth and is subject to a complex interplay that depends on the host genome, nutrition, and life-style. The gut microbiota is involved in the regulation of multiple h...

  • publication . Article . 2007
    Open Access English
    Authors:
    Siepen, Jennifer A; Swainston, Neil; Jones, Andrew R; Hart, Sarah R; Hermjakob, Henning; Jones, Philip; Hubbard, Simon J;
    Publisher: BioMed Central
    Project: WT

    Background Proteomics continues to play a critical role in post-genomic science as continued advances in mass spectrometry and analytical chemistry support the separation and identification of increasing numbers of peptides and proteins from their characteristic mass sp...

  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Pavlova, Elena; Shatunov, Aleksey; Wartosch, Lena; Moskvina, Alena I; Nikolaeva, Lena E; Bright, Nicholas; Tylee, Karen L; Church, Heather J; Ballabio, Andrea; Luzio, John; ...
    Publisher: Oxford University Press (OUP)
    Project: RCUK | Molecular Cell Biology of... (G0900113), WT | High Resolution Imaging i... (093026), WT , WT | Cellular Medicine at the ... (100140), RCUK | Predictive measures to st... (MR/K015338/1), RCUK | Gene Therapy for Tay-Sach... (MR/K025570/1), RCUK | Membrane traffic in the l... (MR/M010007/1)

    <jats:title>Abstract</jats:title> <jats:p>A rare lysosomal disease resembling a mucopolysaccharidosis with unusual systemic features, including renal disease and platelet dysfunction, caused by the defect in a conserved region of the VPS33A gene on human chromosome 12q2...

  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    McDowall, Mark D; Harris, Midori; Lock, Antonia; Rutherford, Kim; Staines, Daniel M; Bähler, Jürg; Kersey, Paul J; Oliver, Stephen; Wood, Valerie;
    Publisher: Nucleic acids research
    Project: WT | The fission yeast databas... (090548)

    PomBase (http://www.pombase.org) is the model organism database for the fission yeast Schizosaccharomyces pombe. PomBase provides a central hub for the fission yeast community, supporting both exploratory and hypothesis-driven research. It provides users easy access to ...

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