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66,370 research outcomes, page 1 of 6,637
  • publication . Preprint . Other literature type . 2018
    Open Access
    Authors:
    Papoutsi, Marina; Magerkurth, Joerg; Josephs, Oliver; Pépés, Sophia E; Ibitoye, Temi; Reilmann, Ralf; Hunt, Nigel; Payne, Edwin; Weiskopf, Nikolaus; Langbehn, Douglas; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: WT

    <jats:title>Abstract</jats:title><jats:p>Non-invasive methods, such as neurofeedback training (NFT), could support cognitive symptom management in Huntington’s disease (HD) by targeting brain regions whose function is impaired. The aim of our single-blind, sham-controll...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Rianne D. Stowell; Grayson O. Sipe; Ryan P. Dawes; Hanna N. Batchelor; Katheryn A. Lordy; Jean M. Bidlack; Edward Brown; Mriganka Sur; Ania K. Majewska;
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | Noradrenergic modulation ... (1F31NS105249-01A1), NSF | Investigating Microglia-s... (1557971), NIH | Contributions of glial ne... (1F32EY028028-01), NIH | Imaging visual plasticity... (5R01EY019277-03), NIH | Interdepartmental Neurosc... (5T32NS007489-10), NIH | Role of P2Y12 and Puriner... (1F31NS086241-01A1), NIH | The effects of arousal on... (5R21NS099973-02)

    <jats:title>Abstract</jats:title><jats:p>Microglia are the innate immune cells of the brain with roles in neuroimmunology and synaptic plasticity. Microglial processes continuously survey the brain parenchyma interacting with synaptic elements and maintaining tissue hom...

  • publication . Preprint . 2020
    Open Access English
    Authors:
    Lucas Poßner; Matthias Laukner; Florian Wilhelmy; Dirk Lindner; Uwe Pliquett; Bojana Petkovic; Marek Ziolkowski; Thomas R. Knösche; Konstantin Weise;
    Publisher: Cold Spring Harbor Laboratory

    <jats:title>Abstract</jats:title><jats:p>The paper presents an experimental study where the distinctness of grey and white matter of an in situ postmortem porcine brain by impedance measurements is investigated. Experimental conditions that would allow to conduct the sa...

  • publication . Article . Preprint . Other literature type . 2016
    Open Access
    Authors:
    Huang, Wen; Mackay, Trudy F. C.;
    Publisher: Public Library of Science (PLoS)
    Project: NIH | QTLs in Drosophila (5R01GM045146-20), NIH | Systems Genetics of Droso... (5R01AG043490-05), NIH | Genetics of Alcohol Sensi... (5R01AA016560-02)

    Classical quantitative genetic analyses estimate additive and non-additive genetic and environmental components of variance from phenotypes of related individuals without knowing the identities of quantitative trait loci (QTLs). Many studies have found a large proportio...

  • publication . Article . Preprint . 2015
    Open Access
    Authors:
    Andersson, Robin; Sandelin, Albin; Danko, Charles G;
    Publisher: Elsevier BV
    Project: EC | SCORA (638273)

    <jats:p>Gene expression is precisely controlled in time and space through the integration of signals that act at gene promoters and gene-distal enhancers. Classically, promoters and enhancers are considered separate classes of regulatory elements, often distinguished by...

  • publication . Preprint . 2018
    Open Access English
    Authors:
    Clara Liao; Ni Y. Feng; Andrew H. Bass;
    Publisher: Cold Spring Harbor Laboratory
    Project: NSF | Molecular-neural basis fo... (1457108)

    <jats:title>ABSTRACT</jats:title><jats:p>Plainfin midshipman fish (<jats:italic>Porichthys notatus</jats:italic>) have a remarkable capacity to generate long duration advertisement calls known as hums, each of which may last for close to two hours and be repeated throug...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Davide Raccuglia; Sheng Huang; Anatoli Ender; Michael-Marcel Heim; Desiree Laber; Agustin Liotta; Stephan J Sigrist; Joerg R P Geiger; David Owald;
    Publisher: Cold Spring Harbor Laboratory

    <jats:p>Slow-wave rhythms characteristic of deep sleep oscillate in the delta band (0.5-4 Hz) and can be found across various brain regions in vertebrates. Across systems it is however unclear how oscillations arise and whether they are the causal functional unit steeri...

  • publication . Preprint . Article . Other literature type . 2019
    Open Access
    Authors:
    Vaughn S. Cooper; Taylor M. Warren; Abigail M. Matela; Michael Handwork; Shani Scarponi;
    Publisher: Cold Spring Harbor Laboratory
    Project: NSF | CAREER: Quantifying pleio... (0845851)

    Evolution is a central, unifying theory for all of life science, yet the subject is poorly represented in most secondary-school biology courses, especially in the United States. One challenge to learning evolution is that it is taught as a conceptual, retrospective subj...

  • publication . Preprint . Other literature type . 2018
    Open Access English
    Authors:
    Kambe, Yuki; Yokai, Masafumi; Takasaki, Ichiro; Kurihara, Takashi; Miyata, Atsuro;
    Publisher: Cold Spring Harbor Laboratory

    <jats:title>Abstract</jats:title><jats:p>Previously, we showed that spinal pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1 receptor signaling triggers long-lasting pain behaviors through astroglial activation. Since astrocyte-neuron lactate shuttle (ANLS...

  • publication . Preprint . Other literature type . 2019
    Open Access
    Authors:
    Aline Muyle; Danelle Seymour; Nikos Darzentas; Elias Primetis; Brandon S. Gaut; Alexandros Bousios;
    Publisher: Cold Spring Harbor Laboratory

    ABSTRACT Plant transposable elements (TEs) regularly capture fragments of host genes. When the host employs siRNAs to silence these TEs, siRNAs homologous to the captured regions may target both the TEs and the genes, potentially leading to their silencing. This epigene...

66,370 research outcomes, page 1 of 6,637
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