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Content Provider: Scientific Reports
(CSV)
  • Funder (18)
  • Project (99+)
  • Publication Date (10)
  • Access Mode (1)
  • Type (11)
  • Language (8)
  • Community (3)
  • Content Provider (100+)
  • Collected From (100+)
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42,765 publications, page 1 of 4,277
  • Aldosterone induces rapid sodium intake by a nongenomic mechanism in the nucleus tractus solitarius

    Article English OPEN
    Qiao, Hu; Hu, Bo; Zhou, Hong; Yan, Jianqun; Jia, Ru; Lu, Bo; Sun, Bo; Luo, Xiao; Fan, Yuanyuan; Wang, Nan; (2016)
    The purpose of this study was to determine whether aldosterone has a rapid action in the nucleus tractus solitarius (NTS) that increases sodium intake, and to examine whether this effect of aldosterone, if present, is mediated by G protein-coupled estrogen receptor (GPE...
  • Brain Tumor Genetic Modification Yields Increased Resistance to Paclitaxel in Physical Confinement

    Article English OPEN
    Bui, Loan; Hendricks, Alissa; Wright, Jamie; Chuong, Cheng-Jen; Davé, Digant; Bachoo, Robert; Kim, Young-tae; (2016)
    Brain tumor cells remain highly resistant to radiation and chemotherapy, particularly malignant and secondary cancers. In this study, we utilized microchannel devices to examine the effect of a confined environment on the viability and drug resistance of the following b...
  • Osteoblast Lineage Cells Play an Essential Role in Periodontal Bone Loss Through Activation of Nuclear Factor-Kappa B

    Article English OPEN
    Pacios, S; Xiao, W; Mattos, M; Lim, J; Tarapore, RS; Alsadun, S; Yu, B; Wang, CY; Graves, DT; (2015)
    Bacterial pathogens stimulate periodontitis, the most common osteolytic disease in humans and the most common cause of tooth loss in adults. Previous studies identified leukocytes and their products as key factors in this process. We demonstrate for the first time that ...
  • Microbiota-based Signature of Gingivitis Treatments: A Randomized Study

    Article English OPEN
    Huang, Shi; Li, Zhen; He, Tao; Bo, Cunpei; Chang, Jinlan; Li, Lin; He, Yanyan; Liu, Jiquan; Charbonneau, Duane; Li, Rui; Xu, Jian; (2016)
    Plaque-induced gingivitis can be alleviated by various treatment regimens. To probe the impacts of various anti-gingivitis treatments on plaque microflora, here a double blinded, randomized controlled trial of 91 adults with moderate gingivitis was designed with two ant...
  • Chronic Activation of the Renin-Angiotensin System Induces Lung Fibrosis

    Article English OPEN
    Wang, Jiaolong; Chen, Li; Chen, Bohao; Meliton, Angelo; Liu, Shu Q.; Shi, Yongyan; Liu, Tianjing; Deb, Dilip K.; Solway, Julian; Chun Li, Yan; (2015)
    Pulmonary fibrosis is a serious lung disorder that can lead to respiratory failure. Here we show that transgenic mice expressing active renin from the liver (RenTgMK) developed progressive pulmonary fibrosis leading to impaired pulmonary function. Histological analyses ...
  • Evolutionary analysis of rubella viruses in mainland China during 2010–2012: endemic circulation of genotype 1E and introductions of genotype 2B

    Article English OPEN
    Zhu, Zhen; Rivailler, Pierre; Abernathy, Emily; Cui, Aili; Zhang, Yan; Mao, Naiyin; Xu, Songtao; Zhou, Shujie; Lei, Yue; Wang, Yan; Zheng, Huanying; He, Jilan; Chen, Ying; Li, Chongshan; Bo, Fang; ... (2015)
    Rubella remains a significant burden in mainland China. In this report, 667 viruses collected in 24 of 31 provinces of mainland China during 2010–2012 were sequenced and analyzed, significantly extending previous reports on limited numbers of viruses collected before 20...
  • The Surface Polarized Graphene Oxide Quantum Dot Films for Flexible Nanogenerators

    Article English OPEN
    Liangbin Liu; Yafei Cheng; Lili Zhu; Shuit-Tong Lee; Fan Liao; Mingwang Shao; (2016)
    Abundant disorderly-distributed surface functional groups, such as hydroxyl, carboxyl, ether and amino groups, endow an isolated graphene oxide quantum dot (GOQD) the polar property due to the symmetry breaking, although the aggregated counterparts present no polarizati...
  • Pharmacokinetics of a multicomponent herbal preparation in healthy Chinese and African volunteers

    Article English OPEN
    Raphael N. Alolga; Yong Fan; Gang Zhang; Jin Li; Yi-Jing Zhao; Jimmy Lelu Kakila; Yan Chen; Ping Li; Lian-Wen Qi; (2015)
    K-601 is an herbal formulation for influenza consisting of Lonicera japonica, Isatis indigotica, Rheum palmatum, Phellodendron chinense, and Scutellaria baicalensis. In this work, we characterized the chemical constituents in K-601, identified the absorbed compounds and...
  • Immuno-targeting the multifunctional CD38 using nanobody

    Article English OPEN
    Li, Ting; Qi, Shali; Unger, Mandy; Hou, Yun Nan; Deng, Qi Wen; Liu, Jun; Lam, Connie M. C.; Wang, Xian Wang; Xin, Du; Zhang, Peng; Koch-Nolte, Friedrich; Hao, Quan; Zhang, Hongmin; Lee, Hon Cheung; Zhao, Yong Juan; (2016)
    CD38, as a cell surface antigen is highly expressed in several hematologic malignancies including multiple myeloma (MM) and has been proven to be a good target for immunotherapy of the disease. CD38 is also a signaling enzyme responsible for the metabolism of two novel ...
  • A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules

    Article English OPEN
    Espana-Agusti, Judit; Tuveson, David A.; Adams, David J.; Matakidou, Athena; (2015)
    Project: WT
    The accelerated discovery of disease-related genes emerging from genomic studies has strained the capacity of traditional genetically engineered mouse models (GEMMs) to provide in-vivo validation. Direct, somatic, genetic engineering approaches allow for accelerated and...
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