Filters (2 )
  • Access Mode (1)
    Clear
  • Research Type (4)
    Clear
  • Funder (16)
  • Project (100)
    Clear
  • Type (7)
  • Language (1)
  • Community (6)
  • Content Provider (100)
  • Access Mode (1)
    Clear
  • Research Type (4)
    Clear
  • Funder (16)
  • Project (100)
    Clear
  • Type (7)
  • Language (1)
  • Community (6)
  • Content Provider (100)
Download Results
241 research outcomes, page 1 of 25
  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Wessel, Jennifer; Chu, Audrey Y; Willems, Sara M; Wang, Shuai; Yaghootkar, Hanieh; Brody, Jennifer A; Dauriz, Marco; Hivert, Marie-France; Raghavan, Sridharan; Lipovich, Leonard; ...
    Publisher: Nature Publishing Group
    Project: NIH | Discovery of Mendelian Dy... (5R01HL107816-02), AKA | Atherosclerosis, insulin ... (77299), NIH | INSULIN RESISTANCE AND AT... (5U01HL047887-08), NWO | Dissecting genetic comple... (2300137747), NIH | Genome-Wide Association f... (5R01HL087641-02), NIH | Insulin Clearance: Candid... (3R01DK079888-02S1), NIH | GCRC-RENOVATION (3M01RR000052-31S3), NIH | CHARGE consortium: gene d... (2R01HL105756-07), NIH | Epidemiology of Precursor... (5K24DK080140-03), NIH | Multi-Ethnic Study of Ath... (3R01HL071205-04S1),...

    Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants on the HumanExome BeadChip in 60,564 non-diabetic individuals and in 16,491 T2D cases and 81,877 controls. We id...

  • publication . Article . Other literature type . 2014
    Open Access English
    Authors:
    Khan, S.; Greco, D.; Michailidou, K.; Milne, R.L.; Muranen, T.A.; Heikkinen, T.; Aaltonen, K.; Dennis, J.; Bolla, M.K.; Liu, J.; ...
    Publisher: Public Library of Science
    Project: NWO | BBMRI-NL (2300154272), NIH | NORTHERN CALIFORNIA COOPE... (5U01CA069417-02), NHMRC | Towards cancer control: P... (199600), NIH | Breast &Prostate Cancer &... (1U01CA098758-01), NHMRC | Epidemiology of Chronic D... (209057), NIH | BIOCHEMICAL MARKERS IN TH... (5U01CA049449-07), NIH | Fine-mapping of 8q24 and ... (5R01CA132839-03), NIH | CALIFORNIA TEACHERS STUDY (5R01CA077398-09), NHMRC | kConFab Follow-Up Project... (454508), NIH | Multiethnic Cohort Study ... (5R37CA054281-13),...

    textabstractGenetic variations, such as single nucleotide polymorphisms (SNPs) in microRNAs (miRNA) or in the miRNA binding sites may affect the miRNA dependent gene expression regulation, which has been implicated in various cancers, including breast cancer, and may al...

  • publication . Article . 2011
    Open Access English
    Authors:
    Duijnisveld, Bouke J.; Bigot, Anne; Beenakker, Karel G M; Portilho, Débora M.; Raz, Vered; van der Heide, Huub J L; Visser, Cornelis P J; Chaouch, Soraya; Mamchaoui, Kamel; Westendorp, Rudi G J; ...
    Publisher: HAL CCSD
    Project: NWO | NCHA Subsidiebesluit 2008... (2300155116)

    International audience; ABSTRACT: INTRODUCTION: Chronic inflammation is a profound systemic modification of the cellular microenvironment which could affect survival, repair and maintenance of muscle stem cells. The aim of this study was to define the role of chronic in...

  • publication . Article . 2013
    Open Access English
    Authors:
    Broer, L.; Demerath, E. W.; Garcia, M. E.; Homuth, G.; Kaplan, R. C.; Lunetta, K. L.; Tanaka, T.; Tranah, G. J.; Walter, S.; Arnold, A. M.; ...
    Publisher: Springer Nature
    Project: NIH | MRI READING CENTER FOR TH... (N01HC015103-007), NWO | NCHA Subsidiebesluit 2008... (2300155116), NWO | Twin-family database for ... (2200125679), NIH | CHS-ULTRASOUND READING (N01HC045133-004), NWO | tweeling onderzoek, met e... (2300133572), NIH | DYNAMICS OF HEALTH, AGING... (N01AG062103-011), NIH | HISPANIC SECONDARY STROKE... (1R01MD009164-01), NIH | CCSP - FIELD CENTER (N01HC055020-003), NIH | COMMUNITY AND COHORT SURV... (N01HC055015-028), NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005),...

    Experimental mild heat shock is widely known as an intervention that results in extended longevity in various models along the evolutionary lineage. Heat shock proteins (HSPs) are highly upregulated immediately after a heat shock. The elevation in HSP levels was shown t...

  • publication . Doctoral thesis . 2016
    Open Access English
    Authors:
    Leeuwen, Elisa;
    Publisher: Erasmus University Rotterdam
    Project: EC | ENGAGE (201413), NWO | Dissecting genetic comple... (2300137747), NWO | NCHA Subsidiebesluit 2008... (2300155116)

    markdownabstractHart- en vaatziekten vormen wereldwijd de belangrijkste oorzaak van morbiditeit en mortaliteit. Risicofactoren voor hart- en vaatziekten zijn vier typen circulerende lipide levels: high-density lipoproteïne cholesterol (HLD-C), low-density lipoproteïne c...

  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Verhaaren, Benjamin F.J.; Debette, Stéphanie; Bis, Joshua C.; Smith, Jennifer A.; Ikram, M. Kamran; Adams, Hieab H.; Beecham, Ashley H.; Rajan, Kumar B.; Lopez, Lorna M.; Barral, Sandra; ...
    Publisher: HAL CCSD
    Project: NIH | Genetic Epidemiology of C... (2R01AG030146-06A1), NIH | MRI READING CENTER FOR TH... (N01HC015103-007), NIH | An Integrated Genetic and... (1R01NS087541-01), NIH | Genome-Wide Association f... (5R01HL087641-02), NIH | CHARGE consortium: gene d... (2R01HL105756-07), EC | ENGAGE (201413), EC | IDEAL (259679), FWF | Genetics of Cerebral Smal... (P 20545), NIH | A Genome-Wide Association... (5R01HL093029-02), NIH | The ARIC and Neurocogniti... (5R01HL070825-03),...

    © 2015 American Heart Association, Inc. Background-The burden of cerebral white matter hyperintensities (WMH) is associated with an increased risk of stroke, dementia, and death. WMH are highly heritable, but their genetic underpinnings are incompletely characterized. T...

  • publication . Article . 2015
    Open Access English
    Authors:
    Mara van Osch; Ton J.M. Rövekamp; Stephanie N. Bergman-Agteres; Liselotte W. Wijsman; Sharon J. Ooms; Simon P. Mooijaart; Joan Vermeulen;
    Project: NWO | NCHA Subsidiebesluit 2008... (2300155116)

    Mara van Osch,1 AJM Rövekamp,2 Stephanie N Bergman-Agteres,1 Liselotte W Wijsman,3,4 Sharon J Ooms,5 Simon P Mooijaart,3,4,6 Joan Vermeulen71Netherlands Institute for Health Services Research, Utrecht, 2Netherlands Organization for Applied Scientific Research, ...

  • publication . Article . 2011
    Open Access English
    Authors:
    Broer, Linda; Koudstaal, Peter J.; Amin, Najaf; Rivadeneira, Fernando; Uitterlinden, Andre G.; Hofman, Albert; Oostra, Ben A.; Breteler, Monique M. B.; Ikram, M. Arfan; van Duijn, Cornelia M.;
    Publisher: Springer Nature
    Project: NWO | NCHA Subsidiebesluit 2008... (2300155116)

    Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, characterized by progressive degeneration of dopaminergic neurons in the substantia nigra and the presence of Lewy bodies in the affected neurons, comprised of aggregated α-synuclein [1, 2]...

  • publication . Doctoral thesis . 2016
    Open Access English
    Authors:
    Springelkamp, Henriët;
    Publisher: Erasmus University Rotterdam
    Project: NWO | NCHA Subsidiebesluit 2008... (2300155116), NWO | Netherlands Institute for... (2300162969)

    markdownabstractOpen-angle glaucoma (OAG) is an important cause of irreversible blindness. In OAG, loss of retinal ganglion cells leads to damage of the optic nerve. This causes visual field loss and eventually blindness. Changes in the optic nerve head (ONH) can be exa...

  • publication . Preprint . Other literature type . 2018
    Open Access English
    Authors:
    Meaghan J Jones; Louie Dinh; Hamid Reza Razzaghian; Olivia de Goede; Julia L MacIsaac; Alexander M. Morin; Kristina Gervin; Raymond Ng; Liesbeth Duijts; Menno C van Zelm; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: EC | DYNAHEALTH (633595), EC | LIFECYCLE (733206), NIH | Epigenetic Pathways to Co... (4R01HD068437-03), EC | ERA-HDHL (696295), NHMRC | Dissecting human B-cell f... (1117687), NWO | NCHA Subsidiebesluit 2008... (2300155116)

    <jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>DNA methylation profiling of peripheral blood leukocytes has many research applications, and characterizing the changes in DNA methylation of specific white blood cell types between ne...

241 research outcomes, page 1 of 25
Last index information