Filters (2 )
  • Access Mode (1)
    Clear
  • Research Type (4)
    Clear
  • Funder (16)
  • Project (100)
    Clear
  • Type (8)
  • Language (1)
  • Community (6)
  • Content Provider (100)
  • Access Mode (1)
    Clear
  • Research Type (4)
    Clear
  • Funder (16)
  • Project (100)
    Clear
  • Type (8)
  • Language (1)
  • Community (6)
  • Content Provider (100)
Download Results
416 research outcomes, page 5 of 42
  • publication . Preprint . 2017
    Open Access English
    Authors:
    Tavallali, Peyman; Razavi, Marianne; Brady, Sean;
    Project: NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005)

    In this article, we propose a new algorithm for supervised learning methods, by which one can both capture the non-linearity in data and also find the best subset model. To produce an enhanced subset of the original variables, an ideal selection method should have the p...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Christina A. Castellani; Ryan J. Longchamps; Jason A. Sumpter; Charles E. Newcomb; John A. Lane; Megan L. Grove; Jan Bressler; Jennifer A. Brody; James S. Floyd; Traci M. Bartz; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | UCLA Clinical and Transla... (5UL1TR000124-04), CIHR , NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005), NIH | Genomics of Cardiac Elect... (4R01HL116747-04), NIH | CHS research resources fo... (3U01HL130114-03S1), NIH | Studies of Rare Genetic V... (5R01HL117626-02), NIH | CHARGE consortium: gene d... (2R01HL105756-07), NIH | Genome-wide study of sudd... (5R01HL092111-03), NIH | CORONARY HEART DISEASE &S... (N01HC085081-016), NIH | Exceptional aging: 12 yea... (5R01AG023629-03),...

    <jats:title>ABSTRACT</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Mitochondrial DNA copy number (mtDNA-CN) has been associated with a variety of aging-related diseases, including all-cause mortality. However, the mechanism by which mtDNA-CN influence...

  • publication . Article . 2016
    Open Access
    Authors:
    Therkelsen, Kate E.; Abraham, Tobin M.; Pedley, Alison; Massaro, Joseph M.; Sutherland, Patrice; Hoffmann, Udo; Fox, Caroline S.;
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Project: NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005)

    Background Prolactin is an anterior pituitary hormone that may modulate the adverse effects of obesity. Prolactin has been associated with cardiovascular disease mortality, but less is known about whether prolactin predicts incidence of cardiovascular disease risk facto...

  • publication . Article . 2017
    Open Access English
    Authors:
    Pardo, Luba M.; Li, Wen-Qing; Hwang, Shih-Jen; Verkouteren, Joris A. C.; Hofman, Albert; Uitterlinden, André G.; Kraft, Peter; Turman, Constance; Han, Jiali; Cho, Eunyoung; ...
    Publisher: Public Library of Science
    Project: NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005), NIH | Life Course Cancer Epidem... (1UM1CA176726-01), NIH | Long Term Multidisciplina... (5UM1CA186107-05), NIH | Premenopausal Hormone Lev... (5R01CA067262-08), NIH | BIOCHEMICAL MARKERS IN TH... (5R01CA049449-02), NIH | Cancer Epidemiology Cohor... (5UM1CA167552-02), NIH | DIET, HORMONES AND RISK O... (3P01CA087969-03S1)

    textabstractThere is strong evidence for a role of environmental risk factors involved in susceptibility to develop multiple keratinocyte cancers (mKCs), but whether genes are also involved in mKCs susceptibility has not been thoroughly investigated. We investigated whe...

  • publication . Article . 2017
    Open Access English
    Authors:
    Murabito, Joanne M.; Rong, Jian; Lunetta, Kathryn L.; Huan, Tianxiao; Lin, Honghuang; Zhao, Qiang; Freedman, Jane E.; Tanriverdi, Kahraman; Levy, Daniel; Larson, Martin G.;
    Publisher: John Wiley and Sons Inc.
    Project: NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005), NIH | Novel multi-omics approac... (2R56AG029451-05A1)

    Summary MicroRNAs (miRNAs) regulate gene expression with emerging data suggesting miRNAs play a role in skeletal muscle biology. We sought to examine the association of miRNAs with grip strength in a community‐based sample. Framingham Heart Study Offspring and Generatio...

  • publication . Article . 2014
    Open Access English
    Authors:
    A. James O'Malley; Felix Elwert; J. Niels Rosenquist; Alan M. Zaslavsky; Nicholas A. Christakis;
    Publisher: BlackWell Publishing Ltd
    Project: NIH | SLEEP AND ENTERTAIMENT OF... (5R01HL064278-04), NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005), NIH | Administrative and Resear... (5P01AG031093-03), NIH | Social Network Study of H... (1R01AG024448-01)

    The identification of causal peer effects (also known as social contagion or induction) from observational data in social networks is challenged by two distinct sources of bias: latent homophily and unobserved confounding. In this paper, we investigate how causal peer e...

  • publication . Article . Other literature type . 2010
    Open Access
    Authors:
    Gloria HOI WAN TSO;
    Publisher: Elsevier BV
    Project: EC | ENGAGE (201413), NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005)

    Bone mineral density (BMD), a diagnostic parameter for osteoporosis and a clinical predictor of fracture, is a polygenic trait with high heritability. To identify genetic variants that influence BMD in different ethnic groups, we performed a genome-wide association stud...

  • publication . Article . 2010
    Open Access
    Authors:
    Lin, Jing-Ping; Zheng, Gang; Joo, Jungnam; Cupples, L. Adrienne;
    Publisher: Portico
    Project: NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005)

    Serum lactate dehydrogenase (LDH) is used in diagnosing many diseases and is significantly determined by genetic factors. Three genes coding for LDH isoenzymes were mapped to chromosome 11q15 and 12p12. We used 330 Framingham Heart Study largest families for microsatell...

  • publication . Article . 2010
    Open Access English
    Authors:
    David Karasik; Yi-Hsiang Hsu; Yanhua Zhou; L Adrienne Cupples; Douglas P Kiel; Serkalem Demissie;
    Publisher: Wiley Subscription Services, Inc., A Wiley Company
    Project: NIH | NEW WAYS TO FIND HUMAN BM... (1R21AR053992-01A2), NIH | Risk Factors for Age Rela... (5R01AR041398-23), NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005), NIH | GENETICS OF BONE STRUCTUR... (1R01AR050066-01)

    Genome-wide association studies offer an unbiased approach to identify new candidate genes for osteoporosis. We examined the Affymetrix 500K + 50K SNP GeneChip marker sets for associations with multiple osteoporosis-related traits at various skeletal sites, including bo...

  • publication . Article . 2013
    Open Access English
    Authors:
    Reardon, Brian J; Hansen, Joyanna G; Crystal, Ronald G; Houston, Denise K; Kritchevsky, Stephen B; Harris, Tamara; Lohman, Kurt; Liu, Yongmei; O’Connor, George T; Wilk, Jemma B; ...
    Publisher: BioMed Central
    Project: NIH | Gene Expression Effect of... (1R03HL095414-01A1), NIH | Nutrition Training (5T32DK007158-35), NIH | Derangements of the Notch... (5P50HL084936-04), NIH | Discovering Pathways of F... (5RC1AG035835-02), NIH | Vitamin D, falls, fractur... (5R01AG029364-02), NIH | Genetic Determinants of V... (5R01AG032098-03), NIH | DYNAMICS OF HEALTH, AGING... (N01AG062103-011), NIH | HEALTH ABC--COORDINATING ... (N01AG062106-019), NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005), NIH | DYNAMICS OF HEALTH .AGING... (N01AG062101-015)

    Background: Vitamin D is associated with lung health in epidemiologic studies, but mechanisms mediating observed associations are poorly understood. This study explores mechanisms for an effect of vitamin D in lung through an in vivo gene expression study, an expression...

416 research outcomes, page 5 of 42
Last index information