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187 research outcomes, page 2 of 19
  • publication . Article . 2015
    Open Access English
    Authors:
    Lemaitre, Rozenn N.; King, Irena B.; Kabagambe, Edmond K.; Wu, Jason H. Y.; McKnight, Barbara; Manichaikul, Ani; Guan, Weihua; Sun, Qi; Chasman, Daniel I.; Foy, Millennia; ...
    Publisher: The American Society for Biochemistry and Molecular Biology
    Project: NIH | Cancer Epidemiology Cohor... (5UM1CA167552-02), NIH | GWAS of longitudinal bloo... (1U01HG004729-01), NIH | Genome-Wide Association f... (5R01HL087641-02), NIH | CHARGE consortium: gene d... (2R01HL105756-07), NIH | CORONARY HEART DISEASE AN... (N01HC085079-023), NIH | Genes of the CYP450-Deriv... (5R01HL084099-04), NIH | Exceptional aging: 12 yea... (5R01AG023629-03), NIH | Prospective meta-analyses... (1R01HL103612-01A1), NIH | A Genome-Wide Association... (5R01HL086694-05), NIH | GWA for Gene-Environment ... (5U01HG004402-02),...

    Very long-chain saturated fatty acids (VLSFAs) are saturated fatty acids with 20 or more carbons. In contrast to the more abundant saturated fatty acids, such as palmitic acid, there is growing evidence that circulating VLSFAs may have beneficial biological properties. ...

  • publication . Article . 2017
    Open Access English
    Authors:
    Paul S. de Vries; Maria Sabater-Lleal; Daniel I. Chasman; Stella Trompet; Tarunveer S. Ahluwalia; Alexander Teumer; Marcus E. Kleber; Ming-Huei Chen; Jie Jin Wang; John R. Attia; ...
    Publisher: PUBLIC LIBRARY SCIENCE
    Project: NHMRC | Blue Mountains Cohort Stu... (457349), NIH | Major Depression: Stage 1... (1R01MH081802-01), NHMRC | Genes and Environment in ... (512423), NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005), NIH | Genome-Wide Association f... (5R01HL087641-02), NIH | HISPANIC SECONDARY STROKE... (1R01MD009164-01), NIH | CHARGE consortium: gene d... (2R01HL105756-07), NHMRC | Eye disease, diet and vas... (974159), NIH | Epidemiology of Precursor... (5K24DK080140-03), NHMRC | Uncovering the aetiology ... (529912),...

    <p>An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associated loci when com...

  • publication . Article . 2018
    Open Access English
    Authors:
    Heidi TM Lai; Marcia C de Oliveira Otto; Rozenn N Lemaitre; Barbara McKnight; Xiaoling Song; Irena B King; Paulo HM Chaves; Michelle C Odden; Anne B Newman; David S Siscovick; ...
    Publisher: BMJ Publishing Group Ltd.
    Project: NIH | CENTRAL BLOOD ANALYSIS LA... (N01HC085086-019), NIH | CHS Events Follow-up Stud... (1U01HL080295-01), NIH | CHS research resources fo... (3U01HL130114-03S1), NIH | CORONARY HEART DISEASE AN... (N01HC085079-023), NIH | Exceptional aging: 12 yea... (5R01AG023629-03), NIH | CORONARY HEART DISEASE &S... (N01HC085083-021), NIH | CHS-Transition Phase -268... (N01HC055222-001), NIH | CORONARY HEART DISEASE &S... (N01HC085080-018), NIH | CORONARY HEART DISEASE &S... (N01HC085081-016), NIH | CORONARY HEART DISEASE AN... (N01HC085082-024)

    <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Objective</jats:title> <jats:p>To determine the longitudinal association between serial biomarker measures of circulating omega 3 polyunsaturated fatty acid (n3-PUFA) levels and healthy ageing.</jats:p> </jats:sec...

  • publication . Article . 2017
    Open Access
    Authors:
    Fohtung, Raymond B.; Brown, David L.; Koh, William J. H.; Bartz, Traci M.; Carbone, Laura D.; Civitelli, Roberto; Stein, Phyllis K.; Chaves, Paulo H. M.; Kestenbaum, Bryan R.; Kizer, Jorge R.;
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Project: NIH | CORONARY HEART DISEASE AN... (N01HC085079-023), NIH | Exceptional aging: 12 yea... (5R01AG023629-03), NIH | CORONARY HEART DISEASE &S... (N01HC085083-021), NIH | CHS-Transition Phase -268... (N01HC055222-001), NIH | CENTRAL BLOOD ANALYSIS LA... (N01HC085086-019), NIH | CHS Events Follow-up Stud... (1U01HL080295-01), NIH | CORONARY HEART DISEASE &S... (N01HC085080-018), NIH | CORONARY HEART DISEASE AN... (N01HC085082-024), NIH | CORONARY HEART DISEASE &S... (N01HC085081-016)

    Background Despite increasing evidence of a common link between bone and heart health, the relationship between bone mineral density (BMD) and heart failure (HF) risk remains insufficiently studied. Methods and Results We investigated whether BMD measured by dual‐energy...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    van Leeuwen, Elisabeth M.; Sabo, Aniko; Bis, Joshua C.; Huffman, Jennifer E.; Manichaikul, Ani; Smith, Albert V.; Feitosa, Mary F.; Demissie, Serkalem; Joshi, Peter K.; Duan, Qing; ...
    Project: EC | IDEAL (259679), NIH | SUBCLINICAL CARDIOVASCULA... (N01HC095167-000), NIH | SUBCLINICAL CARDIOVASCULA... (N01HC095166-002), NIH | Probing The Dark Matter o... (4R01HL117078-04), WT | Identification of genetic... (084723), NIH | SUBCLINICAL CARDIOVASCULA... (N01HC095160-000), NIH | Exceptional aging: 12 yea... (5R01AG023629-03), NIH | Prospective meta-analyses... (1R01HL103612-01A1), NWO | Dissecting genetic comple... (2300137747), EC | EPI-MIGRANT (279143),...

    Background So far, more than 170 loci have been associated with circulating lipid levels through genome-wide association studies (GWAS). These associations are largely driven by common variants, their function is often not known, and many are likely to be markers for th...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Christina A. Castellani; Ryan J. Longchamps; Jason A. Sumpter; Charles E. Newcomb; John A. Lane; Megan L. Grove; Jan Bressler; Jennifer A. Brody; James S. Floyd; Traci M. Bartz; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | UCLA Clinical and Transla... (5UL1TR000124-04), CIHR , NIH | THE FRAMINGHAM HEART STUD... (N01HC025195-005), NIH | Genomics of Cardiac Elect... (4R01HL116747-04), NIH | CHS research resources fo... (3U01HL130114-03S1), NIH | Studies of Rare Genetic V... (5R01HL117626-02), NIH | CHARGE consortium: gene d... (2R01HL105756-07), NIH | Genome-wide study of sudd... (5R01HL092111-03), NIH | CORONARY HEART DISEASE &S... (N01HC085081-016), NIH | Exceptional aging: 12 yea... (5R01AG023629-03),...

    <jats:title>ABSTRACT</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Mitochondrial DNA copy number (mtDNA-CN) has been associated with a variety of aging-related diseases, including all-cause mortality. However, the mechanism by which mtDNA-CN influence...

  • publication . Article . Preprint . Other literature type . 2009
    Open Access
    Authors:
    Kurland, Brenda F.; Johnson, Laura L.; Egleston, Brian L.; Diehr, Paula H.;
    Publisher: Institute of Mathematical Statistics
    Project: NIH | MRI READING CENTER FOR TH... (N01HC015103-007), NIH | CHS-Transition Phase -268... (N01HC055222-001), NIH | CORONARY HEART DISEASE AN... (N01HC085079-023), NIH | CENTRAL BLOOD ANALYSIS LA... (N01HC085086-019), NIH | CHS Events Follow-up Stud... (1U01HL080295-01), NIH | CARDIOVASCULAR HEALTH STU... (N01HC035129-010), NIH | CHS RETINAL READING CENTE... (N01HC075150-001)

    Comment: Published in at http://dx.doi.org/10.1214/09-STS293 the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org)

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Marcus, Gregory; Dixit, S; Stein, PK; Dewland, TA; Dukes, JW; Vittinghoff, E; Heckbert, SR; Marcus, GM;
    Publisher: eScholarship, University of California
    Project: NIH | Exceptional aging: 12 yea... (5R01AG023629-03), NIH | CORONARY HEART DISEASE AN... (N01HC085079-023), NIH | CENTRAL BLOOD ANALYSIS LA... (N01HC085086-019), NIH | CHS Events Follow-up Stud... (1U01HL080295-01), NIH | CORONARY HEART DISEASE AN... (N01HC085082-024), NIH | CORONARY HEART DISEASE &S... (N01HC085081-016), NIH | CORONARY HEART DISEASE &S... (N01HC085080-018), NIH | CORONARY HEART DISEASE &S... (N01HC085083-021), NIH | CHS-Transition Phase -268... (N01HC055222-001), NIH | Clinical and Transtional ... (8TL1TR000144-07)

    Background Premature cardiac contractions are associated with increased morbidity and mortality. Though experts associate premature atrial contractions (PACs) and premature ventricular contractions (PVCs) with caffeine, there are no data to support this relationship in ...

  • publication . Article . 2011
    Open Access
    Authors:
    Shiffman, Dov; O'Meara, Ellen S; Rowland, Charles M; Louie, Judy Z; Cushman, Mary; Tracy, Russell P; Devlin, James J; Psaty, Bruce M;
    Publisher: Springer Nature
    Project: NIH | CENTRAL BLOOD ANALYSIS LA... (N01HC085086-019), NIH | CHS Events Follow-up Stud... (1U01HL080295-01), NIH | CARDIOVASCULAR HEALTH STU... (N01HC035129-010), NIH | CHS RETINAL READING CENTE... (N01HC075150-001), NIH | CHS-ULTRASOUND READING (N01HC045133-004), NIH | CORONARY HEART DISEASE AN... (N01HC085079-023), NIH | CHS-Transition Phase -268... (N01HC055222-001), NIH | MRI READING CENTER FOR TH... (N01HC015103-007)

    Background Genetic risk factors might improve prediction of coronary events. Several variants at chromosome 9p21.3 have been widely reported to be associated with coronary heart disease (CHD) in prospective and case-control studies. A variant of KIF6 (719Arg) has also b...

  • publication . Article . Other literature type . 2010
    Open Access
    Authors:
    Andre Franke; Dermot P B McGovern; Jeffrey C Barrett; Kai Wang; Graham L Radford-Smith; Tariq Ahmad; Charlie W Lees; Tobias Balschun; James Lee; Rebecca Roberts; ...
    Project: NIH | WGA Study to Identify Gen... (5R01HL087652-03), NIH | CORONARY HEART DISEASE AN... (N01HC085079-023), NIH | CHS-ULTRASOUND READING (N01HC045133-004), NIH | CENTRAL BLOOD ANALYSIS LA... (N01HC085086-019), NIH | CHS Events Follow-up Stud... (1U01HL080295-01), NIH | IBD: Genetic and Immunopa... (5P01DK046763-22), NIH | CHS RETINAL READING CENTE... (N01HC075150-001), WT | Statistical and computati... (089120), NIH | MRI READING CENTER FOR TH... (N01HC015103-007), SNSF | Regulation and genetic va... (320030_120463),...

    We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the top association signals in 15,694 cases, 14,026 controls and 414 parent-offspring trios. We i...

187 research outcomes, page 2 of 19
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