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1,192 research outcomes, page 3 of 120
  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Chen, Xiangyang; Liao, Shimiao; Huang, Xinya; Xu, Ting; Feng, Xuezhu; Guang, Shouhong;
    Publisher: Genetics Society of America
    Project: NIH | Caenorhabditis Genetics C... (1P40OD010440-01)

    Rearranged chromosomes have been applied to construct genetic balancers to manipulate essential genes in C. elegans. Although much effort has been put into constructing balancer chromosomes, approximately 6% (map units) of the C. elegans genome has not been covered, and...

  • publication . Article . 2018
    Open Access English
    Authors:
    Yanmei Zhao; Chieh-Hsiang Tan; Amber Krauchunas; Andrea Scharf; Nicholas Dietrich; Kurt Warnhoff; Zhiheng Yuan; Marina Druzhinina; Sam Guoping Gu; Long Miao; ...
    Publisher: Public Library of Science
    Project: NIH | Gamete Interactions in Ca... (5R01HD054681-07), NIH | CDF-1 REGULATION OF ZINC ... (5R01GM068598-06), NIH | Caenorhabditis Genetics C... (1P40OD010440-01), NIH | Biomedical Science Educat... (5K12GM093854-05), NSF | Evolution of Complex Trai... (1021128)

    Sperm activation is a fascinating example of cell differentiation, in which immotile spermatids undergo a rapid and dramatic transition to become mature, motile sperm. Because the sperm nucleus is transcriptionally silent, this transition does not involve transcriptiona...

  • publication . Article . 2015
    Open Access English
    Authors:
    Jason Lieb;
    Publisher: Public Library of Science (PLoS)
    Project: NIH | Basic Mechanisms of Viral... (5T32CA009156-35), NSF | Cell Polarization in Resp... (0917726), NIH | Mechanisms of C. elegans ... (1R01GM083071-01A1), NIH | Caenorhabditis Genetics C... (1P40OD010440-01), NIH | Mechanisms of Asymmetric ... (7R01GM104050-02)

    Author Summary At key moments in development, asymmetric cell divisions give rise to daughter cells of differing characteristics, a process that promotes cell-type diversity in complex organisms. The first cell division of the C. elegans early embryo is a powerful model...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Meital Oren-Suissa; Tamar Gattegno; Veronika Kravtsov; Benjamin Podbilewicz;
    Publisher: Genetics Society of America
    Project: NIH | Caenorhabditis Genetics C... (1P40OD010440-01), EC | ELEGANSFUSION (268843)

    Injury triggers regeneration of axons and dendrites. Research has identified factors required for axonal regeneration outside the CNS, but little is known about regeneration triggered by dendrotomy. Here, we study neuronal plasticity triggered by dendrotomy and determin...

  • publication . Preprint . Article . Other literature type . 2017
    Open Access
    Authors:
    Mangal, Sriyash; Sacher, Jennifer; Kim, Taekyung; Osório, Daniel Sampaio; Motegi, Fumio; Carvalho, Ana Xavier; Oegema, Karen; Zanin, Esther;
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | Kinetochore Specification... (3R01GM074215-05S1), NIH | Kinetochore Specification... (5R01GM074215-03), NIH | Caenorhabditis Genetics C... (1P40OD010440-01), EC | ACTOMYO (640553), NIH | Analysis of Centrosome Dy... (5R01GM074207-02)

    During cytokinesis, centrosomal asters inhibit cortical contractility at the cell poles. Mangal et al. provide molecular insight into this phenomenon, showing that TPXL-1, which localizes to astral microtubules, activates Aurora A kinase to clear contractile ring protei...

  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Dahiya, Yogesh; Rose, Saloni; Thapliyal, Shruti; Bhardwaj, Shivam; Prasad, Maruthi; Babu, Kavita;
    Publisher: Society for Neuroscience
    Project: NIH | Caenorhabditis Genetics C... (1P40OD010440-01)

    Memory formation is crucial for the survival of animals. Here, we study the effect of different crh-1 [Caenorhabditis elegans homolog of mammalian cAMP response element binding protein 1 (CREB1)] isoforms on the ability of C. elegans to form long-term memory (LTM). Null...

  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Simões, Patrícia A.; Celestino, Ricardo; Carvalho, Ana X.; Gassmann, Reto;
    Publisher: The Company of Biologists
    Project: EC | DYNEINOME (338410), NIH | Caenorhabditis Genetics C... (1P40OD010440-01), EC | ACTOMYO (640553)

    Highlighted Article: The sole C. elegans homolog of NudE and NudEL, ubiquitous co-factors of the molecular motor dynein, contributes to chromosome segregation fidelity in early embryogenesis.

  • publication . Doctoral thesis . 2014
    Open Access English
    Authors:
    Waaijers, S.;
    Publisher: Utrecht University
    Project: NIH | Caenorhabditis Genetics C... (1P40OD010440-01), NWO | Defining the protein inte... (2300157240)

    Cell polarity is a fundamental property of cells. The identification of conserved polarity regulators that control polarity in a variety of distinct tissues raises a number of questions. How are the same components used and integrated in tissue-specific ways to give ris...

  • publication . Article . 2016
    Open Access English
    Authors:
    Dillon, James; Holden-Dye, Linda; O'connor, Vincent; Hopper, Neil;
    Publisher: Springer Nature
    Project: WT | Negative regulation of Eg... (064988), NIH | Caenorhabditis Genetics C... (1P40OD010440-01)

    Insulin signalling plays a significant role in both developmental programmes and pathways modulating the neuronal signalling that controls adult behaviour. Here, we have investigated insulin signalling in food-associated behaviour in adult C. elegans by scoring locomoti...

  • publication . Article . 2017
    Open Access English
    Authors:
    Kimberley Laband; Rémi Le Borgne; Frances Edwards; Marine Stefanutti; Julie C. Canman; Jean-Marc Verbavatz; Julien Dumont;
    Publisher: Nature Publishing Group UK
    Project: NIH | Caenorhabditis Genetics C... (1P40OD010440-01)

    During cell division, spindle microtubules ensure an equal repartition of chromosomes between the two daughter cells. While the kinetochore-dependent mechanisms that drive mitotic chromosome segregation are well understood, in oocytes of most species atypical spindles a...

1,192 research outcomes, page 3 of 120
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