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170 research outcomes, page 1 of 17
  • publication . Article . Other literature type . 2012
    Open Access English
    Authors:
    Jonathan Beesley;
    Publisher: HAL CCSD
    Project: EC | RISK FACTORS CANCER (294576), EC | COGS (223175)

    link_to_OA_fulltext

  • publication . Article . 2014
    Open Access English
    Authors:
    Xiaofeng Dai; Ana Chen; Zhonghu Bai;
    Publisher: Nature Publishing Group
    Project: EC | COGS (223175), AKA | GENETIC SUSCEPTIBILITY TO... (132473)

    Exploring the molecular difference among breast cancer subtypes is of crucial importance in understanding its heterogeneity and seeking its effective clinical treatment. For this, several layers of information including immunohistochemical markers and a variety of high-...

  • publication . Other literature type . Article . 2016
    Open Access English
    Authors:
    Shi J; Yanfeng Zhang; Zheng W; Michailidou K; Ghoussaini M; Mk, Bolla; Wang Q; Dennis J; Lush M; Rl, Milne; ...
    Project: CIHR , NIH | Discovery Expansion and R... (5U19CA148065-04), WT | Understanding the genetic... (090532), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | Breast &Prostate Cancer &... (1U01CA098758-01), NHMRC | Epidemiology of Chronic D... (209057), NIH | Breast Cancer Family Regi... (5UM1CA164920-03), NIH | Cancer Risk Reduction and... (2R37CA070867-12), NIH | GENETIC SUSCEPTIBILITY TO... (5U01CA063464-05), NIH | The Nashville Breast Heal... (5R01CA100374-04),...

    Previous genome-wide association studies among women of European ancestry identified two independent breast cancer susceptibility loci represented by single nucleotide polymorphisms (SNPs) rs13281615 and rs11780156 at 8q24. We conducted a fine-mapping study across 2.06 ...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Ugai, Tomotaka; Milne, Roger L; Ito, Hidemi; Aronson, Kristan J; Bolla, Manjeet K; Chan, Tsun; Chan, Ching W; Choi, Ji-Yeob; Conroy, Don M; Dennis, Joe; ...
    Publisher: Wiley
    Project: NIH | Cancer Center Support Gra... (3P30CA068485-21S4), NIH | Follow-up of Ovarian Canc... (3U19CA148112-04S1), NIH | Discovery Expansion and R... (5U19CA148065-04), CIHR , NIH | Elucidating Loci Involved... (5U19CA148537-02), NIH | Shanghai Womens Health St... (1UM1CA182910-01), EC | BRIDGES (634935), NIH | A genome-wide association... (5R01CA128978-02), EC | B-CAST (633784), EC | COGS (223175),...

    BACKGROUND: Epidemiological studies consistently indicate that alcohol consumption is an independent risk factor for female breast cancer (BC). Although the aldehyde dehydrogenase 2 (ALDH2) polymorphism (rs671: Glu>Lys) has a strong effect on acetaldehyde metabolism, th...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Rebbeck, TR; Friebel, TM; Mitra, N; Wan, F; Chen, S; Andrulis, IL; Apostolou, P; Arnold, N; Arun, BK; Barrowdale, D; ...
    Publisher: Springer Nature
    Project: EC | COGS (223175), NIH | Clinical Cancer Genetics ... (1RC4CA153828-01), NIH | Mechanism of Cox-2 Inhibi... (5P50CA083638-09), AKA | Comprehensive analysis of... (266528), NWO | BBMRI-NL (2300154272), NIH | Breast Cancer Family Regi... (5UM1CA164920-03), NIH | Genome-wide association s... (5R01CA142996-03), NIH | Exploiting Biological Net... (1R01CA140323-01A1), NIH | PROPHYLACTIC SURGERY IN C... (5R01CA083855-03), NIH | Discovery Expansion and R... (5U19CA148065-04),...

    published_or_final_version

  • publication . Article . 2011
    Open Access
    Authors:
    Muranen, Taru A.; Greco, Dario; Fagerholm, Rainer; Kilpivaara, Outi; Kampjarvi, Kati; Aittomaki, Kristiina; Blomqvist, Carl; Heikkila, Paivi; Borg, Åke; Nevanlinna, Heli;
    Publisher: Springer Nature
    Project: AKA | GENETIC SUSCEPTIBILITY TO... (132473), EC | COGS (223175)

    Introduction: Checkpoint kinase 2 (CHEK2) is a moderate penetrance breast cancer risk gene, whose truncating mutation 1100delC increases the risk about twofold. We investigated gene copy-number aberrations and gene-expression profiles that are typical for breast tumors ...

  • publication . Article . 2013
    Open Access
    Authors:
    Orozco, Gisela; Goh, Chee L.; Al Olama, Ali Amin; Benlloch-Garcia, Sara; Govindasami, Koveela; Guy, Michelle; Muir, Kenneth R.; Giles, Graham G.; Severi, Gianluca; Neal, David E.; ...
    Publisher: Wiley
    Project: WT | Linking genotype to pheno... (095684), NIH | Elucidating Loci Involved... (5U19CA148537-02), EC | COGS (223175)

    What's known on the subject? and What does the study add? The link between inflammation and cancer has long been reported and inflammation is thought to play a role in the pathogenesis of many cancers, including prostate cancer (PrCa). Over the last 5 years, genome-wide...

  • publication . Article . 2016
    Open Access English
    Authors:
    Castro Elena; Mikropoulos Christos; Bancroft Elizabeth K.; Dadaev Tokhir; Goh Chee; Taylor Natalie; Saunders Edward; Borley Nigel; Keating Diana; Page Elizabeth C.; ...
    Publisher: AlphaMed Press
    Project: NIH | Discovery Expansion and R... (5U19CA148065-04), NIH | Elucidating Loci Involved... (5U19CA148537-02), NIH | Follow-up of Ovarian Canc... (3U19CA148112-04S1), NIH | A genome-wide association... (5R01CA128978-02), CIHR , EC | COGS (223175)

    A better assessment of prostate cancer (PrCa) risk is needed to improve screening. The PROFILE pilot study explored the feasibility of single nucleotide polymorphism profiling in men with a family history (FH) of PrCa to investigate the probability of detecting PrCa at ...

  • publication . Article . 2016
    Open Access English
    Authors:
    Bonilla, C.; Lewis, S. J.; Rowlands, M. A.; Gaunt, T. R.; Davey Smith, G.; Gunnell, D.; Palmer, T.; Donovan, J. L.; Hamdy, F. C.; Neal, D. E.; ...
    Project: CIHR , NIH | Discovery Expansion and R... (5U19CA148065-04), RCUK | Centre for molecular-base... (G0600705), EC | COGS (223175), NIH | Follow-up of Ovarian Canc... (3U19CA148112-04S1), NIH | Elucidating Loci Involved... (5U19CA148537-02)

    What's New? Circulating insulin‐like growth factors (IGF) and their binding proteins have been associated with prostate cancer risk in observational epidemiological studies but it is not clear whether there is a causal relationship with disease. To address this question...

  • publication . Article . 2015
    Open Access English
    Authors:
    Volker Arndt;
    Project: NHMRC | Towards cancer control: P... (199600), NIH | Elucidating Loci Involved... (5U19CA148537-02), CIHR , NHMRC | Molecular Epidemiology of... (400281), NHMRC | Australian Ovarian Cancer... (400413), NIH | Discovery Expansion and R... (5U19CA148065-04), AKA | Finnish Centre of Excelle... (251314), NIH | Follow-up of Ovarian Canc... (3U19CA148112-04S1), NWO | BBMRI-NL (2300154272), NIH | Breast &Prostate Cancer &... (1U01CA098758-01),...

    Immunosuppression plays a pivotal role in assisting tumors to evade immune destruction and promoting tumor development. We hypothesized that genetic variation in the immunosuppression pathway genes may be implicated in breast cancer tumorigenesis. We included 42,510 fem...

170 research outcomes, page 1 of 17
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