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97 research outcomes, page 1 of 10
  • publication . Article . Other literature type . 2011
    Open Access English
    Authors:
    Tianhong Zhou; Shiqian Li; Wenbin Zhong; Terhi Vihervaara; Olivier Béaslas; Julia Perttilä; Wei Luo; Yingliang Jiang; Markku Lehto; Vesa M Olkkonen; ...
    Publisher: Public Library of Science
    Project: EC | LIPIDOMICNET (202272), AKA | Cytoplasmic sterol sensor... (121457)

    We earlier identified OSBP-related protein 8 (ORP8) as an endoplasmic reticulum oxysterol-binding protein implicated in cellular lipid homeostasis. We now investigated its action in hepatic cells in vivo and in vitro. Adenoviral overexpression of ORP8 in mouse liver ind...

  • publication . Article . Other literature type . 2009
    Open Access English
    Authors:
    Perttilä, Julia; Merikanto, Krista; Naukkarinen, Jussi; Surakka, Ida; Martin, Nicolas W.; Tanhuanpää, Kimmo; Grimard, Vinciane; Taskinen, Marja-Riitta; Thiele, Christoph; Salomaa, Veikko; ...
    Publisher: Springer Nature
    Project: EC | LIPIDOMICNET (202272), AKA | Intracellular sterol bind... (118720), WT , AKA | Intracellular sterol bind... (113013), AKA | Cytoplasmic sterol sensor... (121457)

    info:eu-repo/semantics/published

  • publication . Article . 2013
    Open Access English
    Authors:
    Hulstaert, Niels; Reisinger, Florian; Rameseder, Jonathan; Barsnes, Harald; Vizcaíno, Juan Antonio; Martens, Lennart;
    Publisher: ELSEVIER SCIENCE BV
    Project: WT | The Proteomics Identifica... (085949), EC | LIPIDOMICNET (202272), EC | PRIME-XS (262067), EC | PROTEOMEXCHANGE (260558)

    Graphical abstract

  • publication . Article . 2010
    Open Access English
    Authors:
    Abdul-Hammed, Misbaudeen; Breiden, Bernadette; Adebayo, Matthew A.; Babalola, Jonathan O.; Schwarzmann, Günter; Sandhoff, Konrad;
    Publisher: The American Society for Biochemistry and Molecular Biology
    Project: EC | LIPIDOMICNET (202272)

    We examined the effect of Niemann-Pick disease type 2 (NPC2) protein and some late endosomal lipids [sphingomyelin, ceramide and bis(monoacylglycero)phosphate (BMP)] on cholesterol transfer and membrane fusion. Of all lipid-binding proteins tested, only NPC2 transferred...

  • publication . Other literature type . Article . 2010
    Open Access English
    Authors:
    Spandl, Johanna; Lohmann, Daniel; Kuerschner, Lars; Moessinger, Christine; Thiele, Christoph;
    Publisher: American Society for Biochemistry and Molecular Biology
    Project: EC | LIPIDOMICNET (202272)

    Lipid droplets (LDs), the major intracellular storage sites for neutral lipids, consist of a neutral lipid core surrounded by a phospholipid monolayer membrane. In addition to their function in lipid storage, LDs participate in lipid biosynthesis and recently were impli...

  • publication . Article . 2012
    Open Access
    Authors:
    Reisinger, Florian; Krishna, Ritesh; Ghali, Fawaz; Rios, Daniel; Hermjakob, Henning; Vizcaino, Juan Antonio; Jones, Andrew R.;
    Publisher: Wiley
    Project: EC | LIPIDOMICNET (202272), RCUK | Standards-compliant softw... (BB/H024654/1), RCUK | Developing proteome-bioin... (BB/G010781/1), EC | PROTEOMEXCHANGE (260558), WT | The Proteomics Identifica... (085949)

    We present a Java application programming interface (API), jmzIdentML, for the Human Proteome Organisation (HUPO) Proteomics Standards Initiative (PSI) mzIdentML standard for peptide and protein identification data. The API combines the power of Java Architecture of XML...

  • publication . Article . 2013
    Open Access English
    Authors:
    Beaslas, Olivier; Metso, Jari; Nissila, Eija; Laurila, Pirkka-Pekka; Kaiharju, Essi; Batchu, Krishna Chaithanya; Kaipiainen, Leena; Mayranpaa, Mikko I.; Yan, Daoguang; Gylling, Helena; ...
    Publisher: Public Library of Science
    Project: AKA | High-density lipoproteins... (132629), EC | LIPIDOMICNET (202272), AKA | Cytoplasmic sterol sensor... (121457)

    OSBP-related protein 8 (ORP8) encoded by Osbpl8 is an endoplasmic reticulum sterol sensor implicated in cellular lipid metabolism. We generated an Osbpl8(-/-) (KO) C57Bl/6 mouse strain. Wild-type and Osbpl8KO animals at the age of 13-weeks were fed for 5 weeks either ch...

  • publication . Article . 2018
    Open Access English
    Authors:
    Teresa Płatek; Evelyn Orso; Barbara Zapała; Anna Polus; Beata Kieć-Wilk; Monika Piwowar; Monika Chojnacka; Urszula Ciałowicz; Małgorzata Malczewska-Malec; Gerd Schmitz; ...
    Publisher: Wolters Kluwer Health
    Project: EC | LIPIDOMICNET (202272)

    Supplemental Digital Content is available in the text

  • publication . Article . Other literature type . Review . 2012
    Open Access
    Authors:
    Kolter, Thomas;
    Publisher: Hindawi Limited
    Project: EC | LIPIDOMICNET (202272)

    <jats:p>Gangliosides are sialic acid-containing glycosphingolipids. They occur especially on the cellular surfaces of neuronal cells, where they form a complex pattern, but are also found in many other cell types. The paper provides a general overview on their structure...

  • publication . Article . 2012
    Open Access English
    Authors:
    Jeanna Perman Sundelin; Marcus Ståhlman; Annika Lundqvist; Max Levin; Paolo Parini; Martin E. Johansson; Jan Borén;
    Publisher: Public Library of Science
    Project: EC | ETHERPATHS (222639), EC | LIPIDOMICNET (202272)

    Clear-cell renal cell carcinoma (RCC) is, in most cases, caused by loss of function of the tumor suppressor gene von Hippel-Lindau, resulting in constitutive activation of hypoxia-inducible factor (HIF)-1 alpha and expression of hypoxia-induced genes in normoxic conditi...

97 research outcomes, page 1 of 10
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