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82,114 publications, page 5 of 8,212
  • Preprint English OPEN
    Kumarasinghe, Nuwanthika; Moss, Walter N.;
    (2018)
    Publisher: Cold Spring Harbor Laboratory
    ABSTRACT Objective: The pre-mRNA of the Epstein–Barr virus LMP2 ( l atent m embrane p rotein 2) has a region of unusual RNA structure that partially spans two consecutive exons and the entire intervening intron; suggesting RNA folding might affect splicing—particular...
  • Preprint English OPEN
    Stuber, Garret; Decot, Heather; Namboodiri, Vijay; Gao, Wei; McHenry, Jenna; Jennings, Josh; Lee, Sung-Ho; Kantak, Pranish; Kao, Yu-Chieh Jill; Das, Manamita; Witten, Ilana; Deisseroth, Karl; Shih, Yen-Yu Ian;
    (2016)
    Publisher: Cold Spring Harbor Laboratory
    Several neuropsychiatric conditions, such as addiction, schizophrenia, and depression may arise in part from dysregulated activity of ventral tegmental area dopaminergic (THVTA) neurons, as well as from more global maladaptation in neurocircuit function. However, whethe...
  • Preprint English OPEN
    Colmenares, Pío; Baccaro, Fabrício B.; Tourinho, Ana Lúcia;
    (2016)
    Publisher: Cold Spring Harbor Laboratory
    Abstract 1. Arthropod diversity and non-flying arthropod food web are strongly influenced by habitat components related to plant architecture and habitat structural complexity. However, we still poorly understand the relationship between arthropod diversity and the veg...
  • Preprint English OPEN
    Ma, Ming; Futia, Gregory L.; Ozbay, Baris N.; Gibson, Emily A.; Restrepo, Diego;
    (2019)
    Publisher: Cold Spring Harbor Laboratory
    Abstract We used two-photon microscopy to study the role of ensembles of cerebellar molecular layer interneurons (MLIs) in a go-no go task where mice obtain a sugar water reward if they lick a spout in the presence of the rewarded odorant and avoid punishment when they...
  • Preprint English OPEN
    Bendre, Shweta; Rondelet, Arnaud; Hall, Conrad; Schmidt, Nadine; Lin, Yu-Chih; Brouhard, Gary J.; Bird, Alexander W.;
    (2016)
    Publisher: Cold Spring Harbor Laboratory
    Abstract The dynamic regulation of microtubules during mitosis is critical for accurate chromosome segregation and genome stability. Cancer cell lines with hyperstabilized kinetochore microtubules have increased segregation errors and elevated chromosomal instability (...
  • Preprint English OPEN
    Liu, Dechen; Deng, Juan; Zhang, Zhewei; Zhang, Zhi-Yu; Sun, Yan-Gang; Yang, Tianming; Yao, Haishan;
    (2019)
    Publisher: Cold Spring Harbor Laboratory
    ABSTRACT Signaling of expected outcomes in the orbitofrontal cortex (OFC) is critical for outcome-guided and learning behavior. The OFC projects to primary visual cortex (V1), yet the function of this top-down projection is unclear. We found that optogenetic activation...
  • Preprint English OPEN
    Jiang, Zhaodi; Jin, Xiumei; Li, Yuhua; Liu, Sitong; Liu, Xiao-Man; Wang, Yng-Ying; Zhao, Pei; Cai, Xinbin; Liu, Ying; Tang, Yaqi; Sun, Xiaobin; Liu, Yan; Hu, Yanhong; Li, Ming; Cai, Gaihong; ...
    (2019)
    Publisher: Cold Spring Harbor Laboratory
    Single-molecule visualization in cells with genetically encoded tags for electron microscopy (EM) has been a long-awaited but unimplemented tool for cell biologists. Here, we report an approach for directly synthesizing EM-visible gold nanoparticles (AuNPs) on cysteine-...
  • Preprint English OPEN
    Damena, Delesa; Chimusa, Emile R.;
    (2019)
    Publisher: Cold Spring Harbor Laboratory
    ABSTRACT Objective Estimating SNP-heritability ( h 2 g ) of severe malaria/resistance and its distribution across the genome might shed new light in to the underlying biology. Method We investigated h 2 g of severe malaria susceptibility and resistance from...
  • Preprint English OPEN
    Yang, Sichao; Zhang, Meng; Xu, Liqing; Luo, Zhengrong; Zhang, Qinglin;
    (2019)
    Publisher: Cold Spring Harbor Laboratory
    Abstract Persimmon proanthocyanidin (PA) biosynthetic had been reported to be regulated by several transcription factors, but the miRNAs function involved in this process was poorly understood. We identified a miRNA858b that putatively targeted two R2R3-MYB transcripti...
  • Preprint English OPEN
    Caruso, Nicholas M.; Staudhammer, Christina L.; Rissler, Leslie J.;
    (2019)
    Publisher: Cold Spring Harbor Laboratory
    Abstract Amphibian life history traits are affected by temperature and precipitation. Yet, connecting these relationships to population growth, especially for multiple populations within a species, is lacking and precludes our understanding of how amphibians are distri...
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