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82,114 publications, page 4 of 8,212
  • Preprint English OPEN
    Fritsche, Lars G.; Patil, Snehal; Beesley, Lauren J.; VandeHaar, Peter; Salvatore, Maxwell; Peng, Robert B.; Taliun, Daniel; Zhou, Xiang; Mukherjee, Bhramar;
    (2020)
    Publisher: Cold Spring Harbor Laboratory
    Abstract To facilitate scientific collaboration on polygenic risk scores (PRS) research, we created an extensive PRS online repository for 49 common cancer traits integrating freely available genome-wide association studies (GWAS) summary statistics from three sources:...
  • Preprint English OPEN
    Vollebregt, M.A.; Franke, B.; Buitelaar, J.K.; Arnold, L.E.; Faraone, S.V.; Grevet, E.H.; Reif, A.; Zayats, T.; Bralten, J.; Bau, C.H.D.; Haavik, J.; Kuntsi, J.; Cupertino, R.B.; Loo, S.K.; Lundervold, A.J.; ...
    (2019)
    Publisher: Cold Spring Harbor Laboratory
    ABSTRACT Daylight is the strongest synchronizer of human circadian rhythms. The circadian pathway hypothesis posits that synchrony between daylight and the circadian system relates to (in)attention. The dopamine neurotransmitter system is implicated in regulating the c...
  • Preprint English OPEN
    Singh, Inder; Howard, Marc W.;
    (2017)
    Publisher: Cold Spring Harbor Laboratory
    Abstract The classic finding from short-term relative JOR tasks is that correct response time (RT) depends on the lag to the more recent item but not to the less recent item (Hacker, 1980). For decades, researchers have argued that this finding is consistent with a sel...
  • Preprint English OPEN
    Kerdoncuff, Elise; Lambert, Amaury; Achaz, Guillaume;
    (2019)
    Publisher: Cold Spring Harbor Laboratory
    Abstract Only 6% of known species have a conservation status. Methods that assess conservation statuses are often based on individual counts and are thus too laborious to be generalized to all species. Population genomics methods that infer past variations in populatio...
  • Preprint English OPEN
    Song, Chun-Xiao; Yin, Senlin; Ma, Li; Wheeler, Amanda; Chen, Yu; Zhang, Yan; Liu, Bin; Xiong, Junjie; Zhang, Weihan; Hu, Jiankun; Zhou, Zongguang; Dong, Biao; Tian, Zhiqi; Jeffrey, Stefanie S.; Chua, Mei-Sze; ...
    (2017)
    Publisher: Cold Spring Harbor Laboratory
    Abstract 5-Hydroxymethylcytosine (5hmC) is an important mammalian DNA epigenetic modification that has been linked to gene regulation and cancer pathogenesis. Here we explored the diagnostic potential of 5hmC in circulating cell-free DNA (cfDNA) using a sensitive chemi...
  • Preprint English OPEN
    Rashu, Rasheduzzaman; Bhuiyan, Taufiqur Rahman; Hoq, Mohammad Rubel; Hossain, Lazina; Paul, Anik; Khan, Ashraful Islam; Chowdhury, Fahima; Harris, Jason B; Ryan, Edward T; Calderwood, Stephen B; Weil, Ana A; Qadri, Firdausi;
    (2018)
    Publisher: Cold Spring Harbor Laboratory
    Abstract Vibrio cholerae O1 can cause life threatening diarrheal disease if left untreated. A long lasting immune response, producing 3-5 years of protection from subsequent, symptomatic disease following natural infection, is mediated by B cell mediated humoral immun...
  • Preprint English OPEN
    Tragin, Margot; Vaulot, Daniel;
    (2018)
    Publisher: Cold Spring Harbor Laboratory
    ABSTRACT The Ocean Sampling Day (OSD) project provided metabarcoding data for the V4 hyper-variable regions of the 18S rRNA gene from 157 samples collected at 143 mostly coastal stations. In this paper we focus on the class Mamiellophyceae, which was found at nearly al...
  • Preprint English OPEN
    Oosterhof, Nikolaas N.; Connolly, Andrew C.; Haxby, James V.;
    (2016)
    Publisher: Cold Spring Harbor Laboratory
    Abstract Recent years have seen an increase in the popularity of multivariate pattern (MVP) analysis of functional magnetic resonance (fMRI) data, and, to a much lesser extent, magneto-and electro-encephalography (M/EEG) data. We present CoSMoMVPA, a lightweight MVPA (...
  • Preprint English OPEN
    Pehlevan, Cengiz; Ali, Farhan; Ölveczky, Bence P.;
    (2015)
    Publisher: Cold Spring Harbor Laboratory
    Summary Temporally precise movement patterns underlie many motor skills and innate actions, yet the flexibility with which the timing of such stereotyped behaviors can be modified is poorly understood. To probe this, we induced adaptive changes to the temporal structur...
  • Preprint English OPEN
    Zhu, Cuifeng; Liu, Jianguo; Pan, Yong; Fan, Ye; Jin, Leigang; Liu, Yan; Zhang, Zhentian; Gan, Yu; Tang, Wei; Li, Jinhuan; Xiong, Zhuang; Xu, Genming; Lin, Xiuping; Zhang, Yuan; Cai, JinChuan; ...
    (2020)
    Publisher: Cold Spring Harbor Laboratory
    Abstract Background Gut microbiota, mainly characterized by fecal bacterial compositions, affects human immune system and pathophysiological development. Our aim was to measure the quantitative differences of fecal bacterial compositions between osteoporotic patients...
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