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381 projects, page 1 of 39
  • project . 2020 - 2025
    Funder: WT Project Code: 220253
    Funder Contribution: 1,639,850 GBP
    Open Access mandate for Publications
    Partners: University of Glasgow

    Proteins entering the secretory pathway at the endoplasmic reticulum (ER) undergo a vast array of post-translational modifications some of which are essential for correct folding, assembly and secretion. Failure to fulfil these functions results in several diseases due ...

  • project . 2020 - 2025
    Funder: WT Project Code: 220180
    Funder Contribution: 1,393,480 GBP
    Open Access mandate for Publications
    Partners: University of Cambridge

    Protein coding and non-coding RNA can spread between cells and tissues of an organism. RNA mobility between organisms has been documented within and among different kingdoms of life including fungi, plants and animals. However, the underlying mechanisms and roles of suc...

  • project . 2020 - 2024
    Funder: WT Project Code: 218649
    Funder Contribution: 300,000 GBP
    Open Access mandate for Publications
    Partners: University of Birmingham

    Megakaryocytes (MKs) are platelet-producing bone marrow cells with critical roles in the regulation of the bone marrow microenvironment. In myelofibrosis, a progressive and debilitating condition with inadequate treatment, MKs drive extensive fibrosis of the bone marrow...

  • project . 2020 - 2021
    Funder: WT Project Code: 222053
    Funder Contribution: 250,000 USD
    Open Access mandate for Publications
    Partners: Climateworks Foundation

    Healthy Food, Healthy Planet (Europe) (hereafter HFHP) is a collaboration of philanthropic and civil society organizations. Our goal is to support the formation of a movement across Europe advocating for a global food system compatible with climate, health, biodiversity...

  • project . 2020 - 2025
    Funder: WT Project Code: 219556
    Funder Contribution: 1,884,220 GBP
    Open Access mandate for Publications
    Partners: University of Edinburgh

    Protein synthesis is essential for the strengthening and weakening of synaptic connections between neurons, and it is pathologically altered in multiple genetic models of Autism Spectrum Disorders and Intellectual Disability (ASD/ID). The identities of the mRNAs transla...

  • project . 2020 - 2025
    Funder: WT Project Code: 220861
    Funder Contribution: 1,690,790 GBP
    Open Access mandate for Publications
    Partners: King's College London

    In recent years, RNA dynamics in axons and dendrites have arisen as central to neuronal maturation and maintenance of healthy neuronal connectivity. However, the functional roles of transported mRNAs and their binding proteins are scarcely understood. Some of the protei...

  • project . 2020 - 2021
    Funder: WT Project Code: 221304
    Funder Contribution: 2,000,000 INR
    Open Access mandate for Publications
    Partners: Wellcome Trust/dbt India Alliance

    The DBT/Wellcome Trust India Alliance will shortly be organizing the first Conference for Indian Research Managers and Administrators (RMAs), as part of the ongoing India Research Management Initiative (IRMI). IRMI activities represent the foundational steps towards str...

  • project . 2020 - 2025
    Funder: WT Project Code: 220589
    Funder Contribution: 698,120 GBP
    Open Access mandate for Publications
    Partners: University College London

    Gamma-delta T-cells are critical for protecting against carcinogenesis in mice but clinical associations have been equivocal and human trials of gamma-delta T-cell therapy have been disappointing. Previous studies have been limited by unavailable technologies to describ...

  • project . 2020 - 2023
    Funder: WT Project Code: 220415
    Funder Contribution: 2,000,000 GBP
    Open Access mandate for Publications
    Partners: UKRI-MRC

    N/A

  • project . 2020 - 2023
    Funder: WT Project Code: 221483
    Funder Contribution: 120,000 GBP
    Open Access mandate for Publications
    Partners: International Livestock Research Institute, Kenya

    Antimicrobial resistance (AMR) is a global health threat, associated with increased morbidity, mortality, and financial costs. Identifying the potential reservoirs of antibiotic resistance and resistance mechanisms is an important task to tackle AMR. Klebsiella pneumoni...

381 projects, page 1 of 39