search
Include:
44 Research products, page 1 of 5

10
arrow_drop_down
Relevance
arrow_drop_down
  • Closed Access
    Authors: 
    Lorena López-Cerero; Elena Salamanca; Mercedes Delgado-Valverde; José-Manuel Rodríguez-Martínez; Jesús Rodríguez-Baño; Álvaro Pascual;
    Publisher: Springer Nature
    Country: Spain

    Recently, the emergence of an international lineage of the CTX-M-27-producing clade C1 of Escherichia coli ST131 is being observed. The aim is to see if this strain has also been introduced in our area. Twenty-eight (33%) out of 86 individuals from two LTCFs in Seville ...

  • Open Access
    Authors: 
    Jimin Xu; Judith Berastegui-Cabrera; Haiying Chen; Jerónimo Pachón; Jia Zhou; Javier Sánchez-Céspedes;
    Publisher: American Chemical Society (ACS)

    The effective treatment of adenovirus (HAdV) infections in immunocompromised patients still poses great challenges. Herein, we reported our continued efforts to optimize a series of salicylamide derivatives as potent inhibitors of HAdV infection. Of these, nine compound...

  • Open Access
    Authors: 
    Marina R. Pulido; Meritxell García-Quintanilla; Jerónimo Pachón; Michael J. McConnell;
    Publisher: Elsevier
    Country: Spain

    Outer membrane vesicles (OMVs) were isolated from an Acinetobacter strain deficient in lipopolysaccharide (LPS) due to a mutation in lpxD (IB010). Two immunizations with 10 µg of IB010 OMVs elicited total IgG, IgM, IgG1 and IgG2c titers similar to those observed after i...

  • Open Access English
    Authors: 
    Díaz Díaz, S.; Recacha Villamor, Esther; García Duque, A.; Docobo Pérez, Fernando; Blázquez, J.;
    Publisher: Oxford University Press
    Country: Spain

    Background Suppression of SOS response and overproduction of reactive oxygen species (ROS) through detoxification system suppression enhance the activity of fluoroquinolones. Objectives To evaluate the role of both systems in the evolution of resistance to ciprofloxacin...

  • Open Access
    Authors: 
    Jimin Xu; María Eugenia Pachón-Ibáñez; Tania Cebrero-Cangueiro; Haiying Chen; Javier Sánchez-Céspedes; Jia Zhou;
    Publisher: Elsevier

    Carbapenemase-producing Enterobacteriaceae (CPE) represents the most worrisome evolution of the antibiotic resistance crisis, which is almost resistant to most of available antibiotics. This situation is getting even worse particularly due to the recent emergence of col...

  • Open Access
    Authors: 
    Roca Oporto, Cristina; Cebrero Cangueiro, Tania; Gil Marqués, María Luisa; Labrador Herrera, Gema; Smani, Younes; González Roncero, Francisco Manuel; Pachón Díaz, Jerónimo; Pachón Ibáñez, María Eugenia; Cordero Matia, María Elisa;

    Background: S. pneumoniae is the leading cause of community-acquired pneumonia in the solid organ transplant recipient (SOTR); nevertheless, the prevalence of colonization and of the colonizing/infecting serotypes has not been studied in this population. In this context...

  • Open Access
    Authors: 
    Manuela Aguilar-Guisado; José Antonio Marrugal-Lorenzo; Judith Berastegui-Cabrera; Laura Merino; Jerónimo Pachón; Javier Sánchez-Céspedes;
    Publisher: Elsevier
    Country: Spain

    Human adenovirus (HAdV) infection has an important clinical impact in the immunosuppressed population and is associated with high morbidity and mortality rates. The lack of a specific, safe and effective antiviral treatment against HAdV makes necessary the search for ne...

  • Open Access English
    Authors: 
    Tania Cebrero-Cangueiro; Patrice Nordmann; Marta Carretero-Ledesma; Jerónimo Pachón; María Eugenia Pachón-Ibáñez;
    Publisher: Oxford University Press
    Countries: Switzerland, Spain

    This study was carried out as part of our routine work. Authors from the Institute of Biomedicine of Seville, Seville, Spain, are supported by Plan Nacional de I + D+i 2013–2016 and Instituto de Salud Carlos III, Subdirección General de Redes y Centros de Investigación ...

  • Open Access
    Authors: 
    Cristina Cerrada-Romero; Judith Berastegui-Cabrera; Pedro Camacho-Martínez; Josune Goikoetxea-Aguirre; Patricia Pérez-Palacios; Sonia Santibáñez; María José Blanco-Vidal; Adoración Valiente; Jorge Alba; Regino Rodríguez-Álvarez; +8 more
    Publisher: Springer Science and Business Media LLC
    Country: Spain

    The main objective was to evaluate the viability of the SARS-CoV-2 viral particles excreted in stools. In addition, we aimed to identify clinical factors associated with the detection of SARS-CoV-2 RNA in feces, and to determine if its presence is associated with an unf...

  • Open Access
    Authors: 
    Jimin Xu; Judith Berastegui-Cabrera; Na Ye; Marta Carretero-Ledesma; Jerónimo Pachón-Díaz; Haiying Chen; María Eugenia Pachón-Ibáñez; Javier Sánchez-Céspedes; Jia Zhou;
    Publisher: American Chemical Society (ACS)

    An effective therapy for human adenovirus (HAdV) infections in immunocompromised patients and healthy individuals with community-acquired pneumonia remains an unmet medical need. We herein reported a series of novel substituted N-(4-amino-2-chlorophenyl)-5-chloro-2-hydr...