Abstract
This dataset accompanies a manuscript describing a method to predict host-pathogen protein interactions using structure: Host-pathogen protein interactions predicted by comparative modeling. Davis FP, Barkan DT, Eswar N, McKerrow JH, Sali A. Protein Sci (2007) 16:2585-2596. http://www.proteinscience.org/cgi/doi/10.1110/ps.073228407 The files contain predictions made for 10 human pathogens including species of Mycobacterium, Apicomplexa, and Kinetoplastida. The species.all.zip files contain all interactions predictions for each species along with the filter criteria that each interaction passed. The species.filter.zip files contains the same information, but only for the subset of interactions that passed the biological and network-level filters. These files can be viewed in any spreadsheet program, such as Excel. Predictions were made for interactions between human and Mycobacterium tuberculosis: mtuber Mycobacterium leprae: mleprae Leishmania major: lmajor Trypanosoma brucei: tbrucei Trypanosoma cruzi: tcruzi Cryptosporidium hominis: chominis Cryptosporidium parvum: cparvum Plasmodium falciparum: pfalciparum Plasmodium vivax: pvivax Toxoplasma gondii: tgondi