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Search For Huntingtin Interactors In Online Databases – 2018/08/08

Research datakeyboard_double_arrow_right Dataset 08 Aug 2018Publisher:Zenodo

Authors: Harding, Rachel; Arrowsmith, Cheryl; Edwards, Aled;

doi: 10.5281/zenodo.1341882 , 10.5281/zenodo.1341877 , 10.5281/zenodo.1341878

Search For Huntingtin Interactors In Online Databases – 2018/08/08

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Abstract

Dr. Harding is the recipient of the Huntington's Disease Society of America Berman Topper Career Development Fellowship which funds and supports this research. This project is funded and supported with generous funding from the Huntington Society of Canada and the CHDI Foundation. The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.

Project - Huntingtin structure-function open lab notebook. Rationale - To identify different huntingtin interaction partners. Overview - Different online databases which detail protein interaction partners were searched for huntingtin protein interaction partners. Data detailing huntingtin interaction partners from 9 different databases was extracted and simplified – worksheets 1-15. The information from each database was collated – worksheet 16. Huntingtin protein interaction partners were ranked according to the number of databases they were found in as well as the number of different experiments detailing the interaction with huntingtin – worksheet 17.

Related Organizations

University of Toronto
Canada

Keywords

HD, Protein-protein interactions, Huntington's disease, Huntingtin, HTT

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