research data . Dataset . 2019

Analysis of Huntingtin BioID Datasets 2019/04/09

Harding, Rachel; Hesketh, Geoff; Arrowsmith, Cheryl; Edwards, Aled;
Open Access
  • Published: 09 Apr 2019
  • Publisher: Zenodo
Abstract
<p><strong>Project:&nbsp;</strong>Investigation of putative HTT interacting proteins</p> <p><strong>Experiment:&nbsp;</strong>Analysis of HTT BioID datasets&nbsp;</p> <p><strong>Date completed:&shy;&nbsp;</strong>2019/04/09</p> <p><strong>Rationale:&nbsp;</strong>BioID technology employs a promiscuous biotin ligase (BirA) fused to the terminus of the target protein, huntingtin, allowing proximal proteins to be biotinylated and then subsequently identified through mass spectrometry experiments. This technique has not been applied to assess huntingtin interactors to date in the published literature, so will provide a novel methodology to characterize the huntingti...
Subjects
Medical Subject Headings: mental disorderscongenital, hereditary, and neonatal diseases and abnormalities
free text keywords: Huntingtin, Huntington's disease, HD, HTT, BioID, Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Biotechnology, 69999 Biological Sciences not elsewhere classified, 80699 Information Systems not elsewhere classified
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Zenodo
Dataset . 2019
Provider: Datacite
Zenodo
Dataset . 2019
Provider: Datacite
Zenodo
Dataset . 2019
Provider: Datacite
Zenodo
Dataset . 2019
Provider: Zenodo
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research data . Dataset . 2019

Analysis of Huntingtin BioID Datasets 2019/04/09

Harding, Rachel; Hesketh, Geoff; Arrowsmith, Cheryl; Edwards, Aled;