research data . Dataset . 2019

A time-course analysis using Differential Static Light Scattering (DSLS) of purified HTT1-3144 Q23 - 2019/01/28

Harding, Rachel; Arrowsmith, Cheryl; Lee, Matt;
Open Access
  • Published: 28 Jan 2019
  • Publisher: Zenodo
Abstract
<p><strong>Project:&nbsp;</strong>Biophysical investigation of purified HTT protein samples</p> <p><strong>Experiment:&nbsp;</strong>A time-course analysis using Differential Static Light Scattering (DSLS) of purified HTT<sup>1-3144</sup>Q23&nbsp;</p> <p><strong>Date completed:&shy;&nbsp;</strong>2019/01/28</p> <p><strong>Rationale:&nbsp;</strong>Time and resources in the HD field have been primarily focussed on understanding HTT aggregation looking as caspase cleavage products spanning aa. 1-586 or exon 1 spanning aa. 1-90. However, we know that HTT protein purified in its apo form is able to self-associate into larger oligomeric species and that monomer, dimer...
Subjects
free text keywords: DSLS, Differential Static Light Scattering, Huntingtin, HTT, Huntington's disease, Biophysics, Biochemistry, Neuroscience, Ecology, Inorganic Chemistry, 69999 Biological Sciences not elsewhere classified, 39999 Chemical Sciences not elsewhere classified, 29999 Physical Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified
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Dataset . 2019
Provider: Datacite
Zenodo
Dataset . 2019
Provider: Datacite
Zenodo
Dataset . 2019
Provider: Zenodo
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Dataset . 2019
Provider: figshare
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