research data . Dataset . 2016

The Genetic Structure of Leishmania infantum Populations in Brazil and Its Possible Association with the Transmission Cycle of Visceral Leishmaniasis

Eduardo Melim Ferreira, Gabriel; Neves dos Santos, Barbara; Elizabeth Cavalheiros Dorval, Maria; Pompilio Bastos Ramos, Tereza; Porrozzi, Renato; Afranio Peixoto, Alexandre; Cupolillo, Elisa;
  • Published: 01 Jan 2016
  • Publisher: Figshare
Abstract
<div><p><em>Leishmania infantum</em> is the etiologic agent of visceral leishmaniasis (VL) in the Americas, Mediterranean basin and West and Central Asia. Although the geographic structure of <em>L. infantum</em> populations from the Old World have been described, few studies have addressed the population structure of this parasite in the Neotropical region. We employed 14 microsatellites to analyze the population structure of the <em>L. infantum</em> strains isolated from humans and dogs from most of the Brazilian states endemic for VL and from Paraguay. The results indicate a low genetic diversity, high inbreeding estimates and a depletion of heterozygotes, wh...
Subjects
Medical Subject Headings: parasitic diseases
free text keywords: Microbiology, Genetics, Biotechnology, Evolutionary Biology, populations, brazil, visceral, leishmaniasis
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Dataset . 2016
Provider: figshare
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