research data . Dataset . 2016

Ensemble Modeling of the Likely Public Health Impact of a Pre-Erythrocytic Malaria Vaccine

Smith, Thomas; Ross, Amanda; Maire, Nicolas; Chitnis, Nakul; Studer, Alain; Hardy, Diggory; Brooks, Alan; Penny, Melissa; Tanner, Marcel;
  • Published: 01 Jan 2016
  • Publisher: Figshare
Abstract
<div><h3>Background</h3><p>The RTS,S malaria vaccine may soon be licensed. Models of impact of such vaccines have mainly considered deployment via the World Health Organization's Expanded Programme on Immunization (EPI) in areas of stable endemic transmission of <em>Plasmodium falciparum</em>, and have been calibrated for such settings. Their applicability to low transmission settings is unclear. Evaluations of the efficiency of different deployment strategies in diverse settings should consider uncertainties in model structure.</p> <h3>Methods and Findings</h3><p>An ensemble of 14 individual-based stochastic simulation models of <em>P. falciparum</em> dynamics,...
Subjects
Medical Subject Headings: parasitic diseases
free text keywords: Cancer, ensemble, modeling, pre-erythrocytic, malaria
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Dataset . 2016
Provider: figshare
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