Drug Repurposing: A Systematic Approach to Evaluate Candidate Oral Neuroprotective Interventions for Secondary Progressive Multiple Sclerosis

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M. Vesterinen, Hanna ; Connick, Peter ; M. J. Irvine, Cadi ; S. Sena, Emily ; J. Egan, Kieren ; G. Carmichael, Gary ; Tariq, Afiyah ; Pavitt, Sue ; Chataway, Jeremy ; R. Macleod, Malcolm ; Chandran, Siddharthan
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0117705
  • Subject: Uncategorised | neurodegenerative disorders | Max EPA oil | evidence | Neurodegenerative diseases | sclerosis.DesignSystematic review | candidate interventions | Evaluate Candidate Oral Neuroprotective Interventions | Secondary Progressive Multiple Sclerosis ObjectiveTo | neuroprotective drugs | Systematic Approach | neuroprotective therapies | repurposing trials | candidate identification | drug rescue | drug repurposing | Lipoic Acid | ms | summary data

<div><p>Objective</p><p>To develop and implement an evidence based framework to select, from drugs already licenced, candidate oral neuroprotective drugs to be tested in secondary progressive multiple sclerosis.</p><p>Design</p><p>Systematic review of clinical studies o... View more
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