research data . Dataset . 2016

Syndecans Reside in Sphingomyelin-Enriched Low-Density Fractions of the Plasma Membrane Isolated from a Parathyroid Cell Line

A. Podyma-Inoue, Katarzyna; Hara-Yokoyama, Miki; Shinomura, Tamayuki; Kimura, Tomoko; Yanagishita, Masaki;
  • Published: 01 Jan 2016
  • Publisher: Figshare
<div><h3>Background</h3><p>Heparan sulfate proteoglycans (HSPGs) are one of the basic constituents of plasma membranes. Specific molecular interactions between HSPGs and a number of extracellular ligands have been reported. Mechanisms involved in controlling the localization and abundance of HSPG on specific domains on the cell surface, such as membrane rafts, could play important regulatory roles in signal transduction.</p> <h3>Methodology/Principal Findings</h3><p>Using metabolic radiolabeling and sucrose-density gradient ultracentrifugation techniques, we identified [<sup>35</sup>S]sulfate-labeled macromolecules associated with detergent-resistant membranes (...
Medical Subject Headings: carbohydrates (lipids)
free text keywords: Biophysics, Biochemistry, Physics, syndecans, reside, sphingomyelin-enriched, low-density, fractions, plasma, membrane, parathyroid
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Dataset . 2016
Provider: figshare
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