research data . Dataset . 2016

Differential Role of the T6SS in Acinetobacter baumannii Virulence

D. Repizo, Guillermo; Gagné, Stéphanie; Foucault-Grunenwald, Marie-Laure; Borges, Vitor; Charpentier, Xavier; S. Limansky, Adriana; Paulo Gomes, João; M. Viale, Alejandro; P. Salcedo, Suzana;
  • Published: 01 Jan 2016
  • Publisher: Figshare
Abstract
<div><p>Gram-negative bacteria, such as <i>Acinetobacter baumannii</i>, are an increasing burden in hospitals worldwide with an alarming spread of multi-drug resistant (MDR) strains. Herein, we compared a type strain (ATCC17978), a non-clinical isolate (DSM30011) and MDR strains of <i>A</i>. <i>baumannii</i> implicated in hospital outbreaks (Ab242, Ab244 and Ab825), revealing distinct patterns of type VI secretion system (T6SS) functionality. The T6SS genomic locus is present and was actively transcribed in all of the above strains. However, only the <i>A</i>. <i>baumannii</i> DSM30011 strain was capable of killing <i>Escherichia coli</i> in a T6SS-dependent man...
Subjects
Medical Subject Headings: biochemical phenomena, metabolism, and nutrition
free text keywords: Uncategorised, T 6SS, T 6SS manner, DSM 30011, T 6SS genomic locus, Acinetobacter baumannii Virulence, mdr, type VI secretion system, outcompete ATCC 17978, model organism Galleria mellonella, baumannii DSM 30011 strain, ab, T 6SS functionality
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Dataset . 2016
Provider: figshare
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