Stereoselective Rhodium-Catalyzed [3 + 2 + 1] Carbocyclization of Alkenylidenecyclopropanes with Carbon Monoxide: Theoretical Evidence for a Trimethylenemethane Metallacycle Intermediate

Dataset UNKNOWN
Mazumder, Shivnath; Shang, Deju; Negru, Daniela E.; Baik, Mu-Hyun; Evans, P. Andrew;
(2012)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1021/ja305467x.s001, doi: 10.1021/ja305467x.s002, doi: 10.1021/ja305467x.s004
  • Subject: enantioselective reaction | alkylidenecyclopropane proceeds | utility | transition state | Stereoselective | approach | ACP | Space Science | Genetics | Theoretical Evidence | Biophysics | Immunology | bicyclohexenone | carbocyclization | stereoselective construction | stereochemical outcome | carbometalation | Microbiology | Carbon Monoxide | transformation | CO | alkenylidenecyclopropane | ring opening | Trimethylenemethane Metallacycle IntermediateThe | Rh | Biochemistry | validity
    • FOR: 59999 Environmental Sciences not elsewhere classified | 69999 Biological Sciences not elsewhere classified

The theoretically inspired development of a Rh-catalyzed [3 + 2 + 1] carbocyclization of carbon- and heteroatom-tethered alkenylidenecyclopropanes (ACPs) with CO for the stereoselective construction of cis-fused bicyclohexenones is described. This study demo... View more
Share - Bookmark

  • Download from
    figshare via figshare (Dataset, 2012)
  • Cite this research data