AlCl3‑Promoted Selective Michael Addition with Allenoate and Methyleneindolinone: Synthesis of Spirocyclic Oxindole by Using Allenoate as a Four-Carbon Component Building Block

Xu, Shibo; Li, Chunju; Jia, Xueshun; Li, Jian;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1021/jo502209f.s004, doi: 10.1021/jo502209f.s002, doi: 10.1021/jo502209f.s003
  • Subject: Molecular Biology | Inorganic Chemistry | AlCl 3 | Biotechnology | allenoate | Michael Addition | Microbiology | Physiology | chlorine source | Spirocyclic Oxindole | Ecology | spirocyclic | component | Genetics | Biochemistry
    • FOR: 80699 Information Systems not elsewhere classified | 69999 Biological Sciences not elsewhere classified | 39999 Chemical Sciences not elsewhere classified

The AlCl<sub>3</sub>-promoted cyclization of readily available allenoates with methyleneindolinone is disclosed. The present strategy provides a rapid access to spirocyclic oxindole-cyclohexenones in an efficient manner. Remarkably, the allenoate is implemen... View more
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