Iodocyclization of o‑Alkynylbenzamides Revisited: Formation of Isobenzofuran-1(3H)‑imines and 1H‑Isochromen-1-imines Instead of Lactams

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Schlemmer, Claudine; Andernach, Lars; Schollmeyer, Dieter; Straub, Bernd F.; Opatz, Till;
(2012)

The iodocyclization of <i>o</i>-alkynylbenzamides with various electrophiles has been reported to yield five- or six-membered lactams by nucleophilic attack of the amide nitrogen onto the triple bond. While the formation of an isobenzofuran-1­(3<i>H</i>)-imi... View more
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