Copper-Catalyzed Arylation of Benzylic C–H bonds with Alkylarenes as the Limiting Reagents

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Zhang, Wen; Chen, Pinhong; Liu, Guosheng;
(2017)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1021/jacs.7b03781.s004, doi: 10.1021/jacs.7b03781.s003, doi: 10.1021/jacs.7b03781.s002
  • Subject: Biotechnology | room temperature | aryl | bond | group compatibility | substrate scope | Biochemistry | Pharmacology | Copper-Catalyzed Arylation | bioactive compounds | Cancer | Biophysics
    • FOR: 110309 Infectious Diseases | 111714 Mental Health | 60506 Virology | 39999 Chemical Sciences not elsewhere classified

A novel copper-catalyzed aryl­ation of benzylic C–H bonds with nucleo­philic aryl­boronic acids has been developed that provides an efficient way to synthesize various 1,1-diaryl­alkanes with a broad substrate scope and excellent functional group compatibili... View more
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