Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z‑Farnesyl Diphosphate Synthase

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Chan, Yueh-Te; Ko, Tzu-Ping; Yao, Shan-Hsueh; Chen, Ya-Wen; Lee, Cheng-Chung; Wang, Andrew H.-J.;
(2017)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1021/acsomega.6b00562.s007, doi: 10.1021/acsomega.6b00562.s006, doi: 10.1021/acsomega.6b00562.s003, doi: 10.1021/acsomega.6b00562.s005, doi: 10.1021/acsomega.6b00562.s004
  • Subject: Farnesyl diphosphate | Plant Biology | residue H 103 | lavandulyl diphosphate | Ecology | Pharmacology | dimethylallyl thiolodiphosphate | mechanism | Biophysics | structure-based analysis | Δ z FPS-H 103Y | mutagenesis assays | Δ z FPS | FPP | Medicine | Various substrate-binding modes | isopentenyl diphosphate | Potential Head-to-Middle Condensation Function | Irregular products | Biochemistry | Functional switch | crystal structure | head-to-middle reactions | farnesyl diphosphate synthase
    • FOR: 59999 Environmental Sciences not elsewhere classified | 39999 Chemical Sciences not elsewhere classified
    mesheuropmc: education | animal structures

Plants produce a wide variety of secondary metabolites in response to adverse environmental factors. <i>Z</i>,<i>Z</i>-Farnesyl diphosphate (<i>Z</i>,<i>Z</i>-FPP), synthesized by <i>Z</i>,<i>Z</i>-farnesyl diphosphate synthase (<i>z</i>FPS), supports the fo... View more
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