Time-Lapse AFM Imaging of DNA Conformational Changes Induced by Daunorubicin

Audiovisual UNKNOWN
Alonso-Sarduy, Livan; Longo, Giovanni; Dietler, Giovanni; Kasas, Sandor;
(2013)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1021/nl403361f.s006, doi: 10.1021/nl403361f.s007, doi: 10.1021/nl403361f.s005
  • Subject: Molecular Biology | Biotechnology | force microscopy | Intercalating agents bind | DNA molecules | fight cancer | AFM | Space Science | health issue | Biochemistry | Pharmacology | DNA Conformational Changes Induced | Biophysics | intercalating agents
    • FOR: 29999 Physical Sciences not elsewhere classified | 39999 Chemical Sciences not elsewhere classified
    mesheuropmc: food and beverages

Cancer is a major health issue that absorbs the attention of a large part of the biomedical research. Intercalating agents bind to DNA molecules and can inhibit their synthesis and transcription; thus, they are increasingly used as drugs to fight cancer. In ... View more
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