Single Locked Nucleic Acid-Enhanced Nanopore Genetic Discrimination of Pathogenic Serotypes and Cancer Driver Mutations

Audiovisual UNKNOWN
Tian, Kai; Chen, Xiaowei; Luan, Binquan; Singh, Prashant; Yang, Zhiyu; Gates, Kent S.; Lin, Mengshi; Mustapha, Azlin; Gu, Li-Qun;
(2018)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1021/acsnano.8b01198.s002, doi: 10.1021/acsnano.8b01198.s003
  • Subject: Molecular Biology | disease diagnostics | Pathogenic Serotypes | Nucleic Acid-Enhanced Nanopore Genetic Discrimination | Biotechnology | wild-type DNA | STEC | Space Science | nanopore system | Shiga toxin | single-nucleotide polymorphism | SNP discrimination capability | Biophysics | single-nucleotide variations | Escherichia coli | Cancer Driver Mutations | sample preparations | Current LNA applications | Microbiology | Medicine | KRAS G 12D driver mutations | food safety regulation | cancer-derived EGFR L 858R | Computational Biology | base-pair | Current detection methods | LNA nucleotides | nanopore single-molecule sensor | LNA design
    • FOR: 110309 Infectious Diseases | 69999 Biological Sciences not elsewhere classified | 19999 Mathematical Sciences not elsewhere classified | 60506 Virology | 39999 Chemical Sciences not elsewhere classified

Accurate and rapid detection of single-nucleotide polymorphism (SNP) in pathogenic mutants is crucial for many fields such as food safety regulation and disease diagnostics. Current detection methods involve laborious sample preparations and expensive charac... View more
Share - Bookmark

  • Download from
    figshare via figshare (Audiovisual, 2018)
  • Cite this research data