Gadolinium MRI Contrast Agents Based on Triazine Dendrimers: Relaxivity and In Vivo Pharmacokinetics

Audiovisual UNKNOWN
Lim, Jongdoo; Turkbey, Baris; Bernardo, Marcelino; Bryant, L. Henry; Garzoni, Matteo; Pavan, Giovanni M.; Nakajima, Takahito; Choyke, Peter L.; Simanek, Eric E.; Kobayashi, Hisataka;
(2012)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1021/bc300461r.s004, doi: 10.1021/bc300461r.s005, doi: 10.1021/bc300461r.s002, doi: 10.1021/bc300461r.s003
  • Subject: Molecular Biology | PBS | Biotechnology | chelate | vivo r 1 relaxivity | contrast agents | ligand | Marine Biology | Pharmacology | Vivo PharmacokineticsFour gadolinium | DOTA | pharmacokinetic | Immunology | Gd | Gadolinium MRI Contrast Agents | r 1 relaxivity values | r 1 relaxivity | Physiology | Medicine | metalated | DTPA | Computational Biology | Cell Biology | Biochemistry | dendrimer | Cancer
    • FOR: 39999 Chemical Sciences not elsewhere classified

Four gadolinium (Gd)-based macromolecular contrast agents, <b>G3-(Gd-DOTA)</b><sub><b>24</b></sub>, <b>G5-(Gd-DOTA)</b><sub><b>96</b></sub>, <b>G3-(Gd-DTPA)</b><sub><b>24</b></sub>, and <b>G5-(Gd-DTPA)</b><sub><b>96</b></sub>, were prepared that varied in the size of... View more
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