High-Level dCas9 Expression Induces Abnormal Cell Morphology in Escherichia coli

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Cho, Suhyung; Choe, Donghui; Lee, Eunju; Kim, Sun Chang; Palsson, Bernhard; Cho, Byung-Kwan;
(2018)

Along with functional advances in the use of CRISPR/Cas9 for genome editing, endonuclease-deficient Cas9 (dCas9) has provided a versatile molecular tool for exploring gene functions. In principle, differences in cell phenotypes that result from the RNA-guide... View more
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