The Nanoscale Architecture of Force-Bearing Focal Adhesions

Audiovisual UNKNOWN
Hoorn, Hedde van; Harkes, Rolf; Spiesz, Ewa M.; Storm, Cornelis; Noort, Danny van; Ladoux, Benoit; Schmidt, Thomas;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1021/nl5008773.s002, doi: 10.1021/nl5008773.s004, doi: 10.1021/nl5008773.s003, doi: 10.1021/nl5008773.s005
  • Subject: Biotechnology | traction force maps | Physiology | Plant Biology | micropillar array technology | adhesion | Computational Biology | MCF | force exertion | Cell Biology | Genetics | force detection precision | Biochemistry | Cancer | Biophysics | 3 T 3 Fibroblasts
    • FOR: 29999 Physical Sciences not elsewhere classified | 110309 Infectious Diseases | 39999 Chemical Sciences not elsewhere classified

The combination of micropillar array technology to measure cellular traction forces with super-resolution imaging allowed us to obtain cellular traction force maps and simultaneously zoom in on individual focal adhesions with single-molecule accuracy. We ach... View more
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