Straightforward Methodology for the Enantioselective Synthesis of Benzo[a]- and Indolo[2,3-a]quinolizidines

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Amat, Mercedes; M. M. Santos, Maria; Bassas, Oriol; Llor, Núria; Escolano, Carmen; Gómez-Esqué, Arantxa; Molins, Elies; Allin, Steven M.; McKee, Vickie; Bosch, Joan;
(2007)

An enantioselective two-step route to substituted benzo[<i>a</i>]- and indolo[2,3-<i>a</i>]quinolizidines has been developed. It consists of (i) a stereoselective cyclocondensation of a racemic or prochiral δ-oxo(di)ester with either (<i>S</i>)-(3,4-dimethoxypheny... View more
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