Stereoselectivity in (Acyloxy)borane-Catalyzed Mukaiyama Aldol Reactions

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Lee, Joshua M.; Zhang, Xin; Norrby, Per-Ola; Helquist, Paul; Wiest, Olaf;
(2016)

The origin of diastereo- and enantioselectivity in a Lewis acid-catalyzed Mukaiyama aldol reaction is investigated using a combination of dispersion corrected DFT calculations and transition state force fields (TSFF) developed using the quantum guided molecu... View more
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