Lung Adenocarcinoma Cell Responses in a 3D in Vitro Tumor Angiogenesis Model Correlate with Metastatic Capacity

Audiovisual UNKNOWN
Roudsari, Laila C.; Jeffs, Sydney E.; West, Jennifer L.;
(2017)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1021/acsbiomaterials.7b00011.s003, doi: 10.1021/acsbiomaterials.7b00011.s004, doi: 10.1021/acsbiomaterials.7b00011.s002
  • Subject: tumor cell types | nonmetastatic murine 393 P cells | Biotechnology | 549 cells | layer PEG-based hydrogel | cancer cell structures | cell types | 344 SQ cells | lung adenocarcinoma cells | matrix metalloproteinases 2 | vessel recruitment process | metastatic murine 344 SQ cells | 3 D substrates | Space Science | angiogenic growth factors | Vitro Tumor Angiogenesis Model Correlate | cancer cell layer | 344 SQ spheroids | Pharmacology | tumor cells | Biophysics | Immunology | tumor cell spheroids | lung Adenocarcinoma Cell Responses | microvascular tubule networks | Developmental Biology | 393 P cells | Medicine | GGGPQGIWGQGK | RGDS | Hematology | Cell Biology | Biochemistry | 3 D | novel model systems | VEGF | Cancer | tumor angiogenesis model | 3 D hydrogels | metastatic 344 SQ cells
    • FOR: 69999 Biological Sciences not elsewhere classified

Many tools from the field of tissue engineering can be used to develop novel model systems to study cancer. We have utilized biomimetic synthetic hydrogels, based on poly­(ethylene glycol) (PEG) modified with cell adhesive peptides (RGDS) and peptides sensit... View more
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