Bayesian model reveals latent atrophy factors with dissociable cognitive trajectories in Alzheimer’s disease

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Zhang, Xiuming; Mormino, Elizabeth C.; Sun, Nanbo; Sperling, Reisa A.; Sabuncu, Mert R.; Thomas Yeo, B. T.;
  • Subject:
    • lcsh: Brain
    mesheuropmc: nervous system

We used a data-driven Bayesian model to automatically identify distinct latent factors of overlapping atrophy patterns from voxelwise structural MRIs of late-onset Alzheimer’s disease (AD) dementia patients. Our approach estimated the extent to which multiple distinct a... View more
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