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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Rodríguez Garzotto, Analia Adela;

    El síndrome palmo-plantar (SPP) es un efecto adverso, asociado a distintas quimioterapias sistémicas, más frecuentemente secundario a fluoropirimidinas orales como Capecitabina (Xeloda®). Su incidencia se estima entre un 36 y un 68 % de los pacientes sometidos a este tratamiento. Generalmente no amenaza la vida del paciente y rara vez requiere hospitalización.(Childress and Lokich, 2003, Abushullaih et al., 2002) El tratamiento es la suspensión del quimioterápico, modificación de dosis hasta mejoría sintomática y medidas de soporte.(Gressett et al., 2006) La discontinuación del agente causal determina la regeneración de la piel en 1 a 2 semanas, en función del grado y estadio. La fisiopatología del SPP no está establecida. Los cambios clínicos e histológicos que se observan son compatibles con daños en la barrera fisiológica de la piel.(Degen et al., 2010) Entre los hallazgos anatomopatológicos descritos se encuentran cambios inflamatorios inespecíficos como infiltración linfocitaria, dilatación de vasos sanguíneos y edema, marcada hiperqueratosis con paraqueratosis y queratinocitos apoptóticos. (Gressett et al., 2006, Scotte et al., 2005, Scheithauer and Blum, 2004)...

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Docta Complutensearrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Docta Complutense
    Other ORP type . 2017
    Data sources: Docta Complutense
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Docta Complutensearrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Docta Complutense
      Other ORP type . 2017
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Álvarez, Pedro;

    Conferencia impartida en la VIII Feria Internacional de la Castañicultura: Castanea 2017 Bloque temático B. Gestión del castaño

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ BULERIAarrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    BULERIA
    Other ORP type . 2017
    Data sources: BULERIA
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ BULERIAarrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      BULERIA
      Other ORP type . 2017
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Peregalli, Andrés;

    Resumen: En Iberoamérica se implementan políticas públicas sustentadas en la alianza Estado- Sociedad Civil para garantizar el derecho a la educación en sectores vulnerabilizados. Uruguay y Argentina desarrollan “programas puente” y “planes de terminalidad” para que adolescentes, jóvenes y adultos ingresen o re-ingresen a Educación Media o finalicen Secundaria. Se compara la alianza Estado-Sociedad Civil en la co-gestión del Programa Aulas Comunitarias (PAC, Uruguay, 2007) y el Plan de Finalización de Estudios Secundarios para Jóvenes y Adultos (FinEs 2, Argentina, 2008) comprendiendo sus contribuciones y limitaciones a los procesos de inclusión educativa. Se analiza su génesis, diseño político-institucional/modos de organización y formas de co-gestión desde: a) enfoque político-institucional en el análisis de las políticas públicas, b) neoinstitucionalismo: sociopolítico y organizacional e histórico, c) co-gestión, d) gestión educativa (paradigmas: administración y estratégico). Se utiliza metodología cualitativa, siendo la unidad de análisis la co-gestión, hasta diciembre de 2015. Los hallazgos evidencian que PAC y FinEs 2 garantizan el derecho a la educación sustentados en la adhesión de diversos actores y sectores a sus objetivos. La calidad de la contribución de las alianzas difiere según el diseño político-institucional, modo de organización y formas de co-gestión: PAC evidencia una co-gestión estratégica y FinEs 2 una de tipo administración.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Institutional Reposi...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Institutional Repository UCA
    Other ORP type . 2020
    License: CC BY NC SA
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Institutional Reposi...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Institutional Repository UCA
      Other ORP type . 2020
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Diaz Ovalle, Isabel Cristina;

    This master’s thesis aims to set strategies for improving the effectiveness of collection and distribution processes of Bienestarina in Colombia based on the findings made in the case of Bogotá. Presents the result of an analysis and design of management elements that improve the coordination between actors of the supply chain associated with the delivery of the food supplement to the Colombian population, considering that possible inefficiencies in the process of collection and distribution of Bienestarina could have a negative impact on children, young people and adults in vulnerable conditions who require the nutritional supplement. La presente tesis de maestría, de línea Profundización, tiene por objetivo plantear estrategias que le aporten a la efectividad en la gestión de los procesos de acopio y distribución de Bienestarina en Colombia partiendo de los hallazgos realizados al caso de Bogotá. Se presenta el resultado de un análisis y diseño de elementos de gestión que mejoren los niveles de coordinación entre actores de la cadena de suministro relacionada con los procesos asociados a la entrega del suplemento alimenticio a la población colombiana considerando que las posibles ineficiencias en el proceso de acopio y distribución de Bienestarina podrían tener un impacto negativo sobre niños, jóvenes y adultos en condiciones de vulnerabilidad que requieren el suplemento alimenticio. Maestría

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Universidad Nacional...arrow_drop_down
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Universidad Nacional...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Rodríguez Chacón, Jhonathan David;

    This paper presents the measure of the fiscal multiplier on the public Investment of the Sistema General de Regalías (SGR) during the period 2012 to 2018, focus on the Gross Domestic Product and employment in Colombia. The methodology of Auerbach, Gorodnichenko and Murphy (2019) is used, with information on the local investment (SGR) of the state-level in Colombia and the participation of each one is instrumented through the Bartik method to correct endogeneity problems -estimation in 2 stages-. The results show significant multiplier effects for both GDP and employment. During the first year of the investment shock, the GDP multiplier is close to 0.9, while for employment it stands at 1.2, reaching a maximum peak in both cases after the third year (1.2 for GDP and 2.4 for employment). . The estimates presented here are in line with the literature that works on the subject, placing the size of the multiplier in a range between 0.0 and 2.1 with a mean of 0.8 (López, Pinchao and Rodríguez, 2018). El presente trabajo tiene por objeto la medición del multiplicador fiscal de la Inversión del Sistema General de Regalías durante el período 2012 a 2018, sobre el Producto Interno Bruto y el empleo. Se utiliza la metodología de Auerbach, Gorodnichenko y Murphy (2019), con información de la inversión (SGR) local de los departamentos en Colombia y se instrumenta la participación de cada uno mediante el método de Bartik para corregir problemas de endogeneidad -estimación en 2 etapas-. Los resultados muestran efectos multiplicadores significativos tanto para el PIB como para el empleo. Durante el primer año del choque de la inversión, el multiplicador del PIB es cercano a 0.9, mientras que para el empleo se ubica en 1.2, alcanzando un pico máximo en ambos casos después del tercer año (1.2 para el PIB y 2.4 para empleo). Las estimaciones aquí presentes están en línea con la literatura que trabaja el tema, ubicando el tamaño del multiplicador en un rango entre 0.0 y 2.1 con una media de 0.8 (López, Pinchao y Rodríguez, 2018). Maestría

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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Universidad Nacional...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: De Fuentes García-Romero de Tejada, Carlos;

    El presente trabajo aborda los principales retos para lograr la inclusión laboral de las personas con problemas de salud mental grave, cuyas cifras de desempleo y su escasa tasa de actividad son verdaderamente alarmantes y urgen la toma de medidas. Se estudian las diferentes medidas que se han tomado hasta el momento con los Centros de Rehabilitación Laboral y los Centros Especiales de Empleo (CEE). Se analizan los cambios necesarios para que los CEE sean verdaderas empresas inclusivas y promueve como principal desafío la atención temprana del colectivo a través de dispositivos de apoyo al empleo de jóvenes como el que ha puesto en marcha en Alcalá de Henares (Madrid) por Fundación Manantial, inspirado en exitosas experiencias internacionales como la de Melbourne. Se concluye que es preciso la instauración de políticas de empleo activas y pasivas específicas para el colectivo, por ahora inexistentes.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Docta Complutensearrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Docta Complutense
    Other ORP type . 2018
    Data sources: Docta Complutense
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Docta Complutensearrow_drop_down
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      Docta Complutense
      Other ORP type . 2018
      Data sources: Docta Complutense
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Cañadas Fernández, Manuel;

    La actitud negativa y la falta de motivación del alumnado son consideradas posibles causantes de los malos resultados en asignaturas de ciencias. Este Trabajo de Fin de Máster ha diseñado e implementado una metodología activa-motivadora basada en la participación, el uso de herramientas gráficas/multimedia y la incorporación de actividades de dibujo para trabajar de manera transversal competencias como la creatividad y la observación. Además, se ha evaluado si esta metodología mejora las calificaciones del alumnado. De manera paralela, se evalúan los resultados de usar una metodología tradicional. Para ello, se realizó un estudio experimental con diseño pre-test y post-test a 72 alumnos de 1º de la ESO en el IES Domenico Scarlatti (Aranjuez). Se les impartieron 4 sesiones para el estudio de los invertebrados en la asignatura Biología y Geología: dos según metodología activa-motivadora (Poríferos, Platelmintos) y otras dos según metodología tradicional (Cnidarios, Nematodos). El análisis estadístico de los resultados muestra que ambas metodologías mejoran significativamente el aprendizaje. En valores absolutos, los resultados de la metodología activa-motivadora sugieren un incremento en las calificaciones de la evaluación final y en la ratio de mejora con respecto a la metodología tradicional. Atendiendo a los resultados, la estrategia metodológica propuesta en este estudio contribuye a mejorar la motivación, el aprendizaje del alumnado y la adquisición de competencias transversales.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Docta Complutensearrow_drop_down
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    Docta Complutense
    Other ORP type . 2020
    Data sources: Docta Complutense
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Docta Complutensearrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Docta Complutense
      Other ORP type . 2020
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    Authors: Oliver Herrero, José Luís;

    Simulación interactiva en Mathematica del "Mecanismo de Palancas y Colisa de Viatkin para Reproducir una Estrofoide ", número 1137 en el Compendio "Mecanismos en la Técnica Moderna" del Prof. Artobolevsky. Mecanismo plano que forma parte del "Artobolevsky Demonstrations Project", como "Trazador con Deslizaderas" y referencia a-z-1137. La curva que describe el seguidor (color rosa) al accionar el impulsor (color verde) es una "Estrofoide", cuya forma depende de la distancia entre los puntos O y C. El ángulo del impulsor puede variar entre dos posiciones límites. Sus objetivos son: (1) Complementar la descripción del mecanismo existente en el libro mencionado, permitiendo observar su movimiento de forma interactiva; y (2) Proporcionar todos los datos necesarios para poder crear un modelo virtual operativo utilizando un programa de CAD, y llevar a cabo una simulación cinemática mediante un programa de CAE adecuado. Accionando el dial "Angulo Impulsor" se pone en movimiento el cuerpo verde claro, el impulsor, y se observa que el seguidor, cuerpo rosa, se traslada sobre la curva correspondiente mostrada en azul.

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    Authors: Pérez Pita, Alejandro;
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    Authors: Martinez Santos, Cristina;

    La obesidad es una de las enfermedades más prevalentes en países industrialmente desarrollados, considerándose una de las cuatro pandemias del tercer milenio. El sobrepeso/obesidad es causa y consecuencia de otras patologías derivadas como las enfermedades cardiovasculares y metabólicas, diabetes, cáncer, etc. Por ello, la prevención y la predicción de la obesidad se ha convertido en uno de los principales objetivos de la comunidad médico‐científica en las últimas décadas. En la actualidad se conoce el papel crucial que juega el aspecto genético en la obesidad. Sin embargo, el control genético de las formas comunes de obesidad en el humano no se comprende bien. La genética, y en concreto la nutrigenética, nos permite valorar el efecto de diferentes variantes genéticas sobre aspectos íntimamente ligados con el riesgo de obesidad como el control del ciclo saciedad‐hambre, metabolización de hidratos de carbono, grasas, etc. y, por tanto, establecer estrategias para prevenir y disminuir el exceso de peso corporal. El imparable desarrollo de las nuevas tecnologías de análisis de datos por inteligencia artificial, como los árboles de decisión basados en el aprendizaje automático, aportan nuevas herramientas para la predicción de enfermedades. En este sentido, los árboles de decisión, a través del análisis de forma conjunta de las variables no modificables como edad, género y variantes genéticos, podrían estratificar y predecir el riesgo de sobrepeso/obesidad, con el objetivo de diseñar recomendaciones para la prevención de sobrepeso y obesidad...

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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Rodríguez Garzotto, Analia Adela;

    El síndrome palmo-plantar (SPP) es un efecto adverso, asociado a distintas quimioterapias sistémicas, más frecuentemente secundario a fluoropirimidinas orales como Capecitabina (Xeloda®). Su incidencia se estima entre un 36 y un 68 % de los pacientes sometidos a este tratamiento. Generalmente no amenaza la vida del paciente y rara vez requiere hospitalización.(Childress and Lokich, 2003, Abushullaih et al., 2002) El tratamiento es la suspensión del quimioterápico, modificación de dosis hasta mejoría sintomática y medidas de soporte.(Gressett et al., 2006) La discontinuación del agente causal determina la regeneración de la piel en 1 a 2 semanas, en función del grado y estadio. La fisiopatología del SPP no está establecida. Los cambios clínicos e histológicos que se observan son compatibles con daños en la barrera fisiológica de la piel.(Degen et al., 2010) Entre los hallazgos anatomopatológicos descritos se encuentran cambios inflamatorios inespecíficos como infiltración linfocitaria, dilatación de vasos sanguíneos y edema, marcada hiperqueratosis con paraqueratosis y queratinocitos apoptóticos. (Gressett et al., 2006, Scotte et al., 2005, Scheithauer and Blum, 2004)...

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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Álvarez, Pedro;

    Conferencia impartida en la VIII Feria Internacional de la Castañicultura: Castanea 2017 Bloque temático B. Gestión del castaño

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    Authors: Peregalli, Andrés;

    Resumen: En Iberoamérica se implementan políticas públicas sustentadas en la alianza Estado- Sociedad Civil para garantizar el derecho a la educación en sectores vulnerabilizados. Uruguay y Argentina desarrollan “programas puente” y “planes de terminalidad” para que adolescentes, jóvenes y adultos ingresen o re-ingresen a Educación Media o finalicen Secundaria. Se compara la alianza Estado-Sociedad Civil en la co-gestión del Programa Aulas Comunitarias (PAC, Uruguay, 2007) y el Plan de Finalización de Estudios Secundarios para Jóvenes y Adultos (FinEs 2, Argentina, 2008) comprendiendo sus contribuciones y limitaciones a los procesos de inclusión educativa. Se analiza su génesis, diseño político-institucional/modos de organización y formas de co-gestión desde: a) enfoque político-institucional en el análisis de las políticas públicas, b) neoinstitucionalismo: sociopolítico y organizacional e histórico, c) co-gestión, d) gestión educativa (paradigmas: administración y estratégico). Se utiliza metodología cualitativa, siendo la unidad de análisis la co-gestión, hasta diciembre de 2015. Los hallazgos evidencian que PAC y FinEs 2 garantizan el derecho a la educación sustentados en la adhesión de diversos actores y sectores a sus objetivos. La calidad de la contribución de las alianzas difiere según el diseño político-institucional, modo de organización y formas de co-gestión: PAC evidencia una co-gestión estratégica y FinEs 2 una de tipo administración.

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    Authors: Diaz Ovalle, Isabel Cristina;

    This master’s thesis aims to set strategies for improving the effectiveness of collection and distribution processes of Bienestarina in Colombia based on the findings made in the case of Bogotá. Presents the result of an analysis and design of management elements that improve the coordination between actors of the supply chain associated with the delivery of the food supplement to the Colombian population, considering that possible inefficiencies in the process of collection and distribution of Bienestarina could have a negative impact on children, young people and adults in vulnerable conditions who require the nutritional supplement. La presente tesis de maestría, de línea Profundización, tiene por objetivo plantear estrategias que le aporten a la efectividad en la gestión de los procesos de acopio y distribución de Bienestarina en Colombia partiendo de los hallazgos realizados al caso de Bogotá. Se presenta el resultado de un análisis y diseño de elementos de gestión que mejoren los niveles de coordinación entre actores de la cadena de suministro relacionada con los procesos asociados a la entrega del suplemento alimenticio a la población colombiana considerando que las posibles ineficiencias en el proceso de acopio y distribución de Bienestarina podrían tener un impacto negativo sobre niños, jóvenes y adultos en condiciones de vulnerabilidad que requieren el suplemento alimenticio. Maestría

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    Authors: Rodríguez Chacón, Jhonathan David;

    This paper presents the measure of the fiscal multiplier on the public Investment of the Sistema General de Regalías (SGR) during the period 2012 to 2018, focus on the Gross Domestic Product and employment in Colombia. The methodology of Auerbach, Gorodnichenko and Murphy (2019) is used, with information on the local investment (SGR) of the state-level in Colombia and the participation of each one is instrumented through the Bartik method to correct endogeneity problems -estimation in 2 stages-. The results show significant multiplier effects for both GDP and employment. During the first year of the investment shock, the GDP multiplier is close to 0.9, while for employment it stands at 1.2, reaching a maximum peak in both cases after the third year (1.2 for GDP and 2.4 for employment). . The estimates presented here are in line with the literature that works on the subject, placing the size of the multiplier in a range between 0.0 and 2.1 with a mean of 0.8 (López, Pinchao and Rodríguez, 2018). El presente trabajo tiene por objeto la medición del multiplicador fiscal de la Inversión del Sistema General de Regalías durante el período 2012 a 2018, sobre el Producto Interno Bruto y el empleo. Se utiliza la metodología de Auerbach, Gorodnichenko y Murphy (2019), con información de la inversión (SGR) local de los departamentos en Colombia y se instrumenta la participación de cada uno mediante el método de Bartik para corregir problemas de endogeneidad -estimación en 2 etapas-. Los resultados muestran efectos multiplicadores significativos tanto para el PIB como para el empleo. Durante el primer año del choque de la inversión, el multiplicador del PIB es cercano a 0.9, mientras que para el empleo se ubica en 1.2, alcanzando un pico máximo en ambos casos después del tercer año (1.2 para el PIB y 2.4 para empleo). Las estimaciones aquí presentes están en línea con la literatura que trabaja el tema, ubicando el tamaño del multiplicador en un rango entre 0.0 y 2.1 con una media de 0.8 (López, Pinchao y Rodríguez, 2018). Maestría

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    Authors: De Fuentes García-Romero de Tejada, Carlos;

    El presente trabajo aborda los principales retos para lograr la inclusión laboral de las personas con problemas de salud mental grave, cuyas cifras de desempleo y su escasa tasa de actividad son verdaderamente alarmantes y urgen la toma de medidas. Se estudian las diferentes medidas que se han tomado hasta el momento con los Centros de Rehabilitación Laboral y los Centros Especiales de Empleo (CEE). Se analizan los cambios necesarios para que los CEE sean verdaderas empresas inclusivas y promueve como principal desafío la atención temprana del colectivo a través de dispositivos de apoyo al empleo de jóvenes como el que ha puesto en marcha en Alcalá de Henares (Madrid) por Fundación Manantial, inspirado en exitosas experiencias internacionales como la de Melbourne. Se concluye que es preciso la instauración de políticas de empleo activas y pasivas específicas para el colectivo, por ahora inexistentes.

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    Docta Complutense
    Other ORP type . 2018
    Data sources: Docta Complutense
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      Docta Complutense
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    Authors: Cañadas Fernández, Manuel;

    La actitud negativa y la falta de motivación del alumnado son consideradas posibles causantes de los malos resultados en asignaturas de ciencias. Este Trabajo de Fin de Máster ha diseñado e implementado una metodología activa-motivadora basada en la participación, el uso de herramientas gráficas/multimedia y la incorporación de actividades de dibujo para trabajar de manera transversal competencias como la creatividad y la observación. Además, se ha evaluado si esta metodología mejora las calificaciones del alumnado. De manera paralela, se evalúan los resultados de usar una metodología tradicional. Para ello, se realizó un estudio experimental con diseño pre-test y post-test a 72 alumnos de 1º de la ESO en el IES Domenico Scarlatti (Aranjuez). Se les impartieron 4 sesiones para el estudio de los invertebrados en la asignatura Biología y Geología: dos según metodología activa-motivadora (Poríferos, Platelmintos) y otras dos según metodología tradicional (Cnidarios, Nematodos). El análisis estadístico de los resultados muestra que ambas metodologías mejoran significativamente el aprendizaje. En valores absolutos, los resultados de la metodología activa-motivadora sugieren un incremento en las calificaciones de la evaluación final y en la ratio de mejora con respecto a la metodología tradicional. Atendiendo a los resultados, la estrategia metodológica propuesta en este estudio contribuye a mejorar la motivación, el aprendizaje del alumnado y la adquisición de competencias transversales.

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    Docta Complutense
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