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  • Authors: Beaudart, Charlotte; Bruyère, Olivier; Reginster, Jean-Yves; Bauer, J.; +10 Authors
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  • Authors: Barnabé, Fanny;

    À l’heure actuelle, il existe de très nombreuses pratiques créatives par lesquelles les joueurs s’emparent de jeux vidéo afin de produire des œuvres dérivées – qu’il s’agisse de textes, de vidéos, de bandes dessinées ou même d’autres jeux créés à partir d’œuvres vidéoludiques préexistantes. Quelles sont donc ces formes créatives de réception et comment les décrire ? Quelle part du jeu original transforment-elles exactement ? Et quelle relation existe-t-il entre le « jeu » et la « création » (entre jouer et détourner, où placer la frontière) ? C’est à ces questions que le présent article tâchera de répondre.

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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Tcacenco, Andrei;

    My research looks at Soviet republics outside the Russian Federation such as the Ukrainian and Moldavian SSRs, and takes a more localized approach to understanding the state’s campaigns to produce a moral Soviet citizen during the Late Socialist period of Soviet history. I look at how interactions between Soviet citizens in the periphery and Central Party organs resulted in a dynamic, negotiated understanding of socialist morality and concepts of the New Socialist Person in new discursive spaces of home entertainment, especially television and radio. Soviet citizens utilized mass media to spark debates about the meaning of Soviet identity, nationalism and morality, and sometimes to express outright hostility toward the Soviet state. The appropriation of official Soviet language in the periphery led to the creation of new, unpredictable meanings in Soviet discourse. I show that some former Soviet citizens often viewed their national identity as a form of resistance to the Soviet state, while others saw little contradiction between their national and Soviet identities. This paradox is central to my project, as I aim to explore the fluidity, ambiguity, and variation of national and Soviet identity. Ultimately, I argue that the conversations and arguments surrounding morality led to the collapse of the Soviet Union by December 1991.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ eScholarship - Unive...arrow_drop_down
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ eScholarship - Unive...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Geerlings, Nicole M. J.; Zetsche, Eva-Maria; Hidalgo-Martinez, Silvia; Middelburg, Jack J.; +1 Authors

    Cable bacteria are multicellular, filamentous microorganisms that are capable of transporting electrons over centimeter-scale distances. Although recently discovered, these bacteria appear to be widely present in the seafloor, and when active they exert a strong imprint on the local geochemistry. In particular, their electrogenic metabolism induces unusually strong pH excursions in aquatic sediments, which induces considerable mineral dissolution, and subsequent mineral reprecipitation. However, at present, it is unknown whether and how cable bacteria play an active or direct role in the mineral reprecipitation process. To this end we present an explorative study of the formation of sedimentary minerals in and near filamentous cable bacteria using a combined approach of electron microscopy and spectroscopic techniques. Our observations reveal the formation of polyphosphate granules within the cells and two different types of biomineral formation directly associated with multicellular filaments of these cable bacteria: (i) the attachment and incorporation of clay particles in a coating surrounding the bacteria and (ii) encrustation of the cell envelope by iron minerals. These findings suggest a complex interaction between cable bacteria and the surrounding sediment matrix, and a substantial imprint of the electrogenic metabolism on mineral diagenesis and sedimentary biogeochemical cycling. In particular, the encrustation process leaves many open questions for further research. For example, we hypothesize that the complete encrustation of filaments might create a diffusion barrier and negatively impact the metabolism of the cable bacteria.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Copernicus Publicati...arrow_drop_down
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    Copernicus Publications
    Other ORP type . 2019
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Copernicus Publicati...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Copernicus Publications
      Other ORP type . 2019
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • Authors: Dubouclez, Olivier;
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Kamsteeg, Frans; Verbuyst, Rafaël; Wels, Harry;
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Ghent University Aca...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Ghent University Aca...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
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  • Authors: Royen, Virgile;

    Ce récit est le premier de deux articles portant sur la naissance de la politique scientifique en Belgique. Il étudie la mutation du financement et de l'administration de la recherche dans ce pays, d'un modèle de financement privé et d'autogestion par les scientifiques à un modèle de 'Big Science' caractérisé par une forte augmentation du financement public et une direction de la science par les pouvoirs publics. Bestor

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  • Authors: Nyamba, Isaïe; Lechanteur, Anna; Semdé, Rasmé; Evrard, Brigitte;

    Ellagic acid (EA) is a polyphenolic active compound with antimalarial and other promising therapeutic activities. However, its solubility and its permeability are both low (BCS IV). These properties greatly compromise its oral bioavailability and clinical utilizations. To overcome these limitations of the physicochemical parameters, several formulation approaches, including particle size reduction, amorphization and lipid-based formulations, have been used. Although these strategies have not yet led to a clinical application, some of them have resulted in significant improvements in the solubility and bioavailability of EA. This critical review reports and analyses the different formulation approaches used by scientists to improve both the biopharmaceutical properties and the clinical use of EA.

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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Li, Sihuan;

    Extremely large scale scientific simulation applications have been very important in many scientific domains including cosmology, climate, fluid dynamics, chemistry and so on. It has been shown that running the simulations at a larger scale can bring more discoveries. On one hand, with the increasing scale of those applications, the saturated I/O bandwidth can slow down the execution of the simulation significantly because of the huge amount of data needed to be dumped to the storage system. On the other hand, soft errors striking the simulations are not negligible considering the great number of components in the supercomputer and a single scientific execution spending days to finish. Therefore, it is meaningful to reduce the I/O time and harden the resilience of those large scale simulations. Though hardware solutions like designing new storage systems or error resilient computing devices have great generality, it usually takes longer development time and much more effort than software solutions. This thesis seeks software solutions by designing efficient and resilient lossy compressors for large scale scientific simulations.To improve the overall simulation performance, we propose a better lossy compressor which has a much higher compression ratio to reduce the I/O time significantly. More specifically, we focus on particle based scientific simulations. As we know, greater compression ratios imply less data to be written to the storage system which in turn, reduces I/O time. The state-of-art lossy compressor takes the advantage of spatial smoothness to achieve high compression ratios. However, particle based simulations have very limited smoothness in space which leads to inadequate compression ratios. In contrast, we propose to exploit smoothness in time for lossy compression and design an optimized compression model based on the existing lossy compressor. Results show our optimized compression model achieves much better compression ratios and significantly reduces I/O time at large scale.To improve the resilience of the simulation applications equipped with lossy compression, we design soft error resilient schemes for lossy compressors. First, we provide an algorithm-scope protection for one widely used lossy compressor named SZ. Then, we provide an application-scope protection that can be applied to all error-bounded lossy compressors. The algorithm-scope protection can only cover soft errors happening during the execution of the lossy compression itself while the application-scope protection can cover soft errors during simulation, lossy compression and even data writing. Both the algorithm- scope and the application-scope protections can provide significantly better resilience but keep the performance overhead low.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ eScholarship - Unive...arrow_drop_down
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  • Authors: Hecquet, Corentin; Klaedtke, Stéphanie;
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  • Authors: Beaudart, Charlotte; Bruyère, Olivier; Reginster, Jean-Yves; Bauer, J.; +10 Authors
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  • Authors: Barnabé, Fanny;

    À l’heure actuelle, il existe de très nombreuses pratiques créatives par lesquelles les joueurs s’emparent de jeux vidéo afin de produire des œuvres dérivées – qu’il s’agisse de textes, de vidéos, de bandes dessinées ou même d’autres jeux créés à partir d’œuvres vidéoludiques préexistantes. Quelles sont donc ces formes créatives de réception et comment les décrire ? Quelle part du jeu original transforment-elles exactement ? Et quelle relation existe-t-il entre le « jeu » et la « création » (entre jouer et détourner, où placer la frontière) ? C’est à ces questions que le présent article tâchera de répondre.

    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Tcacenco, Andrei;

    My research looks at Soviet republics outside the Russian Federation such as the Ukrainian and Moldavian SSRs, and takes a more localized approach to understanding the state’s campaigns to produce a moral Soviet citizen during the Late Socialist period of Soviet history. I look at how interactions between Soviet citizens in the periphery and Central Party organs resulted in a dynamic, negotiated understanding of socialist morality and concepts of the New Socialist Person in new discursive spaces of home entertainment, especially television and radio. Soviet citizens utilized mass media to spark debates about the meaning of Soviet identity, nationalism and morality, and sometimes to express outright hostility toward the Soviet state. The appropriation of official Soviet language in the periphery led to the creation of new, unpredictable meanings in Soviet discourse. I show that some former Soviet citizens often viewed their national identity as a form of resistance to the Soviet state, while others saw little contradiction between their national and Soviet identities. This paradox is central to my project, as I aim to explore the fluidity, ambiguity, and variation of national and Soviet identity. Ultimately, I argue that the conversations and arguments surrounding morality led to the collapse of the Soviet Union by December 1991.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ eScholarship - Unive...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ eScholarship - Unive...arrow_drop_down
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    Authors: Geerlings, Nicole M. J.; Zetsche, Eva-Maria; Hidalgo-Martinez, Silvia; Middelburg, Jack J.; +1 Authors

    Cable bacteria are multicellular, filamentous microorganisms that are capable of transporting electrons over centimeter-scale distances. Although recently discovered, these bacteria appear to be widely present in the seafloor, and when active they exert a strong imprint on the local geochemistry. In particular, their electrogenic metabolism induces unusually strong pH excursions in aquatic sediments, which induces considerable mineral dissolution, and subsequent mineral reprecipitation. However, at present, it is unknown whether and how cable bacteria play an active or direct role in the mineral reprecipitation process. To this end we present an explorative study of the formation of sedimentary minerals in and near filamentous cable bacteria using a combined approach of electron microscopy and spectroscopic techniques. Our observations reveal the formation of polyphosphate granules within the cells and two different types of biomineral formation directly associated with multicellular filaments of these cable bacteria: (i) the attachment and incorporation of clay particles in a coating surrounding the bacteria and (ii) encrustation of the cell envelope by iron minerals. These findings suggest a complex interaction between cable bacteria and the surrounding sediment matrix, and a substantial imprint of the electrogenic metabolism on mineral diagenesis and sedimentary biogeochemical cycling. In particular, the encrustation process leaves many open questions for further research. For example, we hypothesize that the complete encrustation of filaments might create a diffusion barrier and negatively impact the metabolism of the cable bacteria.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Copernicus Publicati...arrow_drop_down
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    Copernicus Publications
    Other ORP type . 2019
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      Copernicus Publications
      Other ORP type . 2019
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • Authors: Dubouclez, Olivier;
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    Authors: Kamsteeg, Frans; Verbuyst, Rafaël; Wels, Harry;
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Ghent University Aca...arrow_drop_down
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  • Authors: Royen, Virgile;

    Ce récit est le premier de deux articles portant sur la naissance de la politique scientifique en Belgique. Il étudie la mutation du financement et de l'administration de la recherche dans ce pays, d'un modèle de financement privé et d'autogestion par les scientifiques à un modèle de 'Big Science' caractérisé par une forte augmentation du financement public et une direction de la science par les pouvoirs publics. Bestor

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  • Authors: Nyamba, Isaïe; Lechanteur, Anna; Semdé, Rasmé; Evrard, Brigitte;

    Ellagic acid (EA) is a polyphenolic active compound with antimalarial and other promising therapeutic activities. However, its solubility and its permeability are both low (BCS IV). These properties greatly compromise its oral bioavailability and clinical utilizations. To overcome these limitations of the physicochemical parameters, several formulation approaches, including particle size reduction, amorphization and lipid-based formulations, have been used. Although these strategies have not yet led to a clinical application, some of them have resulted in significant improvements in the solubility and bioavailability of EA. This critical review reports and analyses the different formulation approaches used by scientists to improve both the biopharmaceutical properties and the clinical use of EA.