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The THAP proteins family is characterised by the presence of a protein motif, designed the THAP domain, conserved during evolution and found in a thousand of human and model animal organism proteins. Human THAP1 protein is a regulator of the cell cycle through pRB/E2F p...

L'IRM cardiovasculaire, malgré son émergence récente, occupe une place de plus en plus importante en routine clinique. Elle se distingue des autres modalités d'imagerie par son innocuité, son excellente résolution spatiale, son bon contraste et par sa capacité d'imager ...

Membres du Jury: P.Labastie (LCAR Toulouse, France) :président B.Huber (Ciril,Caen,France) :rapporteur F.Martin (UAM, Madrid, Espagne) :Rapporteur M.Farizon (IPNL, Lyon, France) S.Martin (LASIM, Lyon, France) P.Moretto-Capelle (LCAR, Toulouse) :Dir. de thèse; A quantita...

The Spectral Clustering consists in creating, from the spectral elements of a Gaussian affinity matrix, a low-dimension space in which data are grouped into clusters. This unsupervised method is mainly based on Gaussian affinity measure, its parameter and its spectral e...

Public clouds enable storing and sharing data with efficient cost and high availability. Nevertheless the benefits, cloud providers are recurrently breached by malicious users exposing sensitive user content. To mitigate the lack of security guarantees, users can impose...

Obtenue avec la mention très honorable avec les félicitations du jury à l'unanimité; Based on a 4-year ethnography conducted in a GEM ("groupe d'entraide mutuelle", i.e. mutual help group) located in a major French city, this investigation focuses on the institutional a...

In this thesis we are interested to the study of spectral accumulation phenomena of some opeators coming from quantum physics, namely Schrödinger, Paul and Dirac operators. Typically, these operators appear in the modeling of some physical problems in the form of evolut...

In this manuscript, we present a shape optimization method based on CAD parameters such as lengths, angles, etc. We rely on gradient-based optimization techniques. The sensitivity of the objective function, with respect to the mesh nodes position, is provided by an adjo...

Vegetable oils like camelina and sunflower oils are sources of healthy polyunsaturated fatty acids that are however highly susceptible to oxidative degradation. This work aimed at enhancing the oxidative stability of edible oils, mostly camelina oil by incorporating phe...