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  • Open Access
    Authors: 
    Taylor-Walker, George; Lynn, Savannah A.; Keeling, Eloise; Munday, Rosie; Johnston, David A.; Page, Anton; Scott, Jennifer A.; Goverdhan, Srini; Lotery, Andrew J.; Ratnayaka, J. Arjuna;
    Publisher: Elsevier BV
    Country: United Kingdom
    Project: UKRI | Exploitation of an ex-viv... (NC/L001152/1)

    Age-related Macular Degeneration (AMD) is a common, irreversible blinding condition that leads to the loss of central vision. AMD has a complex aetiology with both genetic as well as environmental risks factors, and share many similarities with Alzheimer's disease. Rece...

  • Open Access English
    Authors: 
    Silke Langenheder; Mark T. Bulling; James I. Prosser; Martin Solan;
    Publisher: BioMed Central
    Countries: United Kingdom, Sweden
    Project: UKRI | Marine biodiversity-ecosy... (NE/E006795/1)

    Abstract Background Theory suggests that biodiversity can act as a buffer against disturbances and environmental variability via two major mechanisms: Firstly, a stabilising effect by decreasing the temporal variance in ecosystem functioning due to compensatory processe...

  • Open Access English
    Authors: 
    Oliver T. Hogg; Veerle A.I. Huvenne; Huw J. Griffiths; Boris Dorschel; Katrin Linse;
    Publisher: Nature Publishing Group
    Country: United Kingdom
    Project: EC | CODEMAP (258482), UKRI | SPITFIRE - the Southampto... (NE/L002531/1), NSF | Collaborative Research: R... (1246111)

    Global biodiversity is in decline, with the marine environment experiencing significant and increasing anthropogenic pressures. In response marine protected areas (MPAs) have increasingly been adopted as the flagship approach to marine conservation, many covering enormo...

  • Open Access English
    Authors: 
    Stella, Massimo; Beckage, Nicole M.; Brede, Markus;
    Country: United Kingdom
    Project: UKRI | A Doctoral Training Centr... (EP/G03690X/1)

    Network models of language have provided a way of linking cognitive processes to the structure and connectivity of language. However, one shortcoming of current approaches is focusing on only one type of linguistic relationship at a time, missing the complex multi-relat...

  • Open Access English
    Authors: 
    Gavin L. Foster; Philip F Sexton;
    Country: United Kingdom
    Project: UKRI | Climate Change and the Oc... (NE/D00876X/2), UKRI | Role of Ocean Biogeochemi... (NE/I006346/1)

    Biological productivity and carbon export in the equatorial Atlantic are thought to have been dramatically higher during the last glacial period than during the Holocene. Here we reconstruct the pH and CO2 content of surface waters from the eastern equatorial Atlantic O...

  • Open Access English
    Authors: 
    Zeidan, Bashar; Manousopoulou, Antigoni; Garay-Baquero, Diana J; White, Cory H; Larkin, Samantha E T; Potter, Kathleen N; Roumeliotis, Theodoros I; Papachristou, Evangelia K; Copson, Ellen; Cutress, Ramsey I; +4 more
    Publisher: Apollo - University of Cambridge Repository
    Country: United Kingdom
    Project: UKRI | Manchester Academic Healt... (MR/M008959/1)

    BackgroundEarly-onset breast cancer (EOBC) affects about one in 300 women aged 40 years or younger and is associated with worse outcomes than later onset breast cancer. This study explored novel serum proteins as surrogate markers of prognosis in patients with EOBC.Meth...

  • Open Access English
    Authors: 
    Kowalczykowski, Stephen Charles; Cole, Daniel J.; Rajendra, Eason; Roberts-Thomson, Meredith; Hardwick, Bryn; McKenzie, Grahame J.; Payne, Mike C.; Venkitaraman, Ashok R.; Skylaris, Chris-Kriton;
    Publisher: Public Library of Science (PLoS)
    Country: United Kingdom
    Project: UKRI | Cambridge Condensed Matte... (EP/F032773/1)

    The breast cancer suppressor BRCA2 controls the recombinase RAD51 in the reactions that mediate homologous DNA recombination, an essential cellular process required for the error-free repair of DNA double-stranded breaks. The primary mode of interaction between BRCA2 an...

  • Publication . Article . Preprint . 2020 . Embargo End Date: 01 Jan 2019
    Open Access
    Authors: 
    David J. Lusher; Neil D. Sandham;
    Publisher: arXiv
    Country: United Kingdom
    Project: UKRI | Peta-5: A National Facili... (EP/P020259/1)

    Numerical work on shockwave/boundary-layer interactions (SBLIs) to date has largely focused on span-periodic quasi-2D configurations that neglect the influence lateral confinement has on the core flow. The present study is concerned with the effect of flow confinement o...

  • Publication . Article . Preprint . 2021
    Open Access
    Authors: 
    Xiong, Yifeng; Ng, Soon Xin; Hanzo, Lajos;
    Publisher: Institute of Electrical and Electronics Engineers (IEEE)
    Country: United Kingdom
    Project: UKRI | Converged Optical and Wir... (EP/P003990/1), EC | QuantCom (789028), UKRI | New Air Interface Techniq... (EP/P034284/1)

    Quantum error mitigation (QEM) is a class of promising techniques capable of reducing the computational error of variational quantum algorithms tailored for current noisy intermediate-scale quantum computers. The recently proposed permutation-based methods are practical...

  • Publication . Preprint . Article . 2019 . Embargo End Date: 01 Jan 2019
    Open Access
    Authors: 
    Sam A. Berry; Lewis G. Carpenter; Alan C. Gray; Pete Smith; Corin B. E. Gawith;
    Publisher: arXiv
    Country: United Kingdom
    Project: UKRI | ESCHER - Establishing Sup... (EP/R041636/1)

    We present a metallic zinc indiffused diced ridge waveguide in magnesium doped periodically poled lithium niobate (MgO:PPLN) capable of generating over 1 W of 780 nm with 70% efficiency. Our 40 mm long waveguide has near circular fundamental mode output with diameter 10...