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40 research outcomes, page 1 of 4
  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Touret, Franck; Gilles, Magali; Barral, Karine; Nougairède, Antoine; van Helden, Jacques; Decroly, Etienne; de Lamballerie, Xavier; Coutard, Bruno;
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | EVA-GLOBAL (871029)

    International audience; A novel coronavirus, named SARS-CoV-2, emerged in 2019 in China and rapidly spread worldwide. As no approved therapeutics exists to treat COVID-19, the disease associated to SARS-Cov-2, there is an urgent need to propose molecules that could quic...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Guillaume Castel; Mathilde Couteaudier; Frank Sauvage; Jean-Baptiste Pons; Séverine Murri; Angelina Plyusnina; Dominique Pontier; Jean-François Cosson; Alexander Plyusnin; Philippe Marianneau; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: Finland, France
    Project: EC | ANTIGONE (278976), EC | EDENEXT (261504), ANR | ECOFECT (ANR-11-LABX-0048), ANR | Avenir L.S.E. (ANR-11-IDEX-0007)

    Puumala virus (PUUV) is the agent of nephropathia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) in Europe. NE incidence presents a high spatial variation throughout France, while the geographical distribution of the wild reservoir of PUUV, ...

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  • publication . Article . 2016
    Open Access
    Authors:
    Hamzić , E.; Kjæ rup, R.B.; Mach, N.; Minozzi, G.; Strozzi, F.; Gualdi, V.; Williams, J.L.; Chen, J.; ...
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Countries: Italy, France
    Project: EC | NADIR (228394)

    BackgroundAvian infectious bronchitis (IB) is an acute and highly contagious disease of the upper-respiratory tract caused by infectious bronchitis virus (IBV). Understanding the molecular mechanisms involved in the immune response to IBV infection is a crucial element ...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Melanie Eck; Margarita García Durán; Meret E. Ricklin; Samira Locher; Javier Sarraseca; María José Morillo Rodríguez; Kenneth C. McCullough; Artur Summerfield; Gert Zimmer; Nicolas Ruggli;
    Persistent Identifiers
    Publisher: BioMed Central
    Countries: Switzerland, France
    Project: EC | PORRSCON (245141)

    International audience; AbstractPorcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of one of the most devastating and economically significant viral disease of pigs worldwide. The vaccines currently available on the market elicit only lim...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Bonfante, Francesco; Mazzetto, Eva; Zanardello, Claudia; Fortin, Andrea; Gobbo, Federica; Maniero, Silvia; Bigolaro, Michela; Davidson, Irit; Haddas, Ruth; Cattoli, Giovanni; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | ANIHWA (291815)

    Since 1997, G1-lineage H9N2 avian influenza viruses have been circulating in Asia and later on in the Middle East, and they have been associated to mild respiratory disease, drops in egg production and moderate mortality in chickens, in particular in the presence of con...

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  • publication . Article . 2015
    Open Access
    Authors:
    Foley, N; Thong, V; Soisook, P; Goodman, S; Armstrong, K; Jacobs, D; Puechmaille, Sébastien; Teeling, Emma;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Country: France
    Project: EC | AGELESS (311000), SFI | A comparative genomic inv... (06/YI3/B932)

    The phylogenetic and taxonomic relationships among the Old World leaf-nosed bats (Hipposideridae) and the closely related horseshoe bats (Rhinolophidae) remain unresolved. In this study, we generated a novel approximately 10-kb molecular data set of 19 nuclear exon and ...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Yves Levy; Aurélie Wiedemann; Boris P. Hejblum; Mélany Durand; Cécile Lefebvre; Mathieu Surenaud; Christine Lacabaratz; Matthieu Perreau; Emile Foucat; Marie Dechenaud; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | CARE (101005077)

    The identification of patients with coronavirus disease 2019 and high risk of severe disease is a challenge in routine care. We performed cell phenotypic, serum, and RNA sequencing gene expression analyses in severe hospitalized patients (n = 61). Relative to healthy do...

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  • publication . Article . 2016
    Open Access
    Authors:
    Bioglio L; Génois M; Cl, Vestergaard; Poletto C; Barrat A; Vittoria Colizza;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Countries: France, Italy
    Project: EC | PREDEMICS (278433), ANR | Amidex (ANR-11-IDEX-0001), EC | MULTIPLEX (317532), ANR | HarMS-flu (ANR-12-MONU-0018)

    Background The homogeneous mixing assumption is widely adopted in epidemic modelling for its parsimony and represents the building block of more complex approaches, including very detailed agent-based models. The latter assume homogeneous mixing within schools, workplac...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Medve, Laura; Achilli, Silvia; Serna, Sonia; Zuccotto, Fabio; Varga, Norbert; Thépaut, Michel; Civera, Monica; Vivès, Corinne; Fieschi, Franck; Reichardt, Niels; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: Italy, France
    Project: EC | IMMUNOSHAPE (642870)

    International audience; A library of mannose- and fucose-based glycomimetics was synthesized and screened in a microarray format against a set of C-type lectin receptors (CLRs) that included DC-SIGN, DC-SIGNR, langerin, and dectin-2. Glycomimetic ligands able to interac...

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  • publication . Preprint . Article . 2018
    Open Access English
    Authors:
    Giancarlo De Luca; Kim Van Kerckhove; Pietro Coletti; Chiara Poletto; Nathalie Bossuyt; Niel Hens; Vittoria Colizza;
    Publisher: Cold Spring Harbor Laboratory
    Countries: France, Belgium, France, France, France
    Project: EC | TransMID (682540), EC | PREDEMICS (278433), ANR | HarMS-flu (ANR-12-MONU-0018)

    Background: School closure is often considered as an option to mitigate influenza epidemics because of its potential to reduce transmission in children and then in the community. The policy is still however highly debated because of controversial evidence. Moreover, the...

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40 research outcomes, page 1 of 4