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We propose that a chemically agnostic approach to explore the origin of life, using an automated recursive platform based on droplet microfluidics, could be used to induce artificial chemical evolution by iterations of growth, speciation, selection, and propagation. To ...

Aims. Acetylsalicylic acid (ASA) is widely used for the prevention of atherothrombotic events in patients with chronic coronary artery disease (CAD) and peripheral artery disease (PAD), but the risk of vascular events remains high. We aimed at identifying randomised con...

The work presents a review on the technological advancements of functional electrical stimulation (FES) neuroprostheses\ud to restore gait walking over the last decades. The aim of an FES intervention is to functionally restore and rehabilitate individuals with\ud motor...

Mortality from neurodegenerative disease is high among professional soccer players, potentially associated with repeated head impacts during routine gameplay. New data suggest that the apolipoprotein E ε4 allele might exacerbate the effects of soccer ball heading on cog...

Marine plastic pollution is currently a major scientific focus, with attention paid to its distribution and impacts within ecosystems. With recent estimates indicating that the mass of plastic released to the marine environment may reach 250 million metric tons by 2025,...

Gait and balance impairment is highly prevalent in older people. We aimed to assess whether and how single markers of small vessel disease (SVD) or a combination thereof explain gait and balance function in the elderly. We analysed 678 community-dwelling healthy subject...

T cell receptor (TCR) stimulation by pMHC complexes on antigen presenting cells (APC), requires precise re-organisation of molecules into the area of cellular contact to form an immunological synapse from where T cell signaling is initiated. Caveolin-1 (Cav1), a widely ...

Hypertension (high blood pressure) is a major public health problem affecting more than a billion people worldwide with complications, including stroke, heart failure and kidney failure. The regulation of blood pressure is multifactorial reflecting genetic susceptibilit...

No abstract available.

Obtaining a better understanding of the underlying dynamics of the interaction of turbulent flows and the bed surface that contains them, leading to the transport of coarse particles in fluvial, coastal, and aeolian environments, is considered as one of the fundamental ...