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6 research outcomes, page 1 of 1
  • publication . Article . 2021
    Open Access English
    Authors:
    Yves Levy; Aurélie Wiedemann; Boris P. Hejblum; Mélany Durand; Cécile Lefebvre; Mathieu Surenaud; Christine Lacabaratz; Matthieu Perreau; Emile Foucat; Marie Dechenaud; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | CARE (101005077)

    The identification of patients with coronavirus disease 2019 and high risk of severe disease is a challenge in routine care. We performed cell phenotypic, serum, and RNA sequencing gene expression analyses in severe hospitalized patients (n = 61). Relative to healthy do...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Muhammad Umar B. Niazi; Alain Y. Kibangou; Carlos Canudas-de-Wit; Denis Nikitin; Liudmila Tumash; Pierre-Alexandre Bliman;
    Persistent Identifiers
    Country: France
    Project: EC | Scale-FreeBack (694209)

    Testing is a crucial control mechanism in the beginning phase of an epidemic when the vaccines are not yet available. It enables the public health authority to detect and isolate the infected cases from the population, thereby limiting the disease transmission to suscep...

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  • publication . Article . 2021
    English
    Authors:
    Dimarco, Giacomo; Perthame, Benoît; Toscani, Giuseppe; Zanella, Mattia;
    Publisher: HAL CCSD
    Country: France
    Project: EC | ADORA (740623)

    International audience; Motivated by the COVID-19 pandemic, we introduce a mathematical description of the impact of sociality in the spread of infectious diseases by integrating an epidemiological dynamic with a kinetic modeling of population-based contacts. The kineti...

  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Andreas Dräger; Tomáš Helikar; Matteo Barberis; Marc R. Birtwistle; Laurence Calzone; Claudine Chaouiya; Jan Hasenauer; Jonathan R. Karr; Anna Niarakis; María Rodríguez Martínez; ...
    Publisher: Zenodo
    Country: France
    Project: EC | HELICAL (813545), NIH | A predictive multi-scale ... (5R35GM119770-02), EC | iPC (826121), EC | COSMIC (765158), NIH | Toward whole-cell models ... (5R35GM119771-02)

    Summary: Computational models of biological systems can exploit on a broad range of rapidly developing approaches, including novel experimental approaches, bioinformatics data analysis, emerging modelling paradigms, data standards, and algorithms. A discussion about the...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Romain Marlin; Véronique Godot; Sylvain Cardinaud; Mathilde Galhaut; Severin Coleon; Sandra Zurawski; Nathalie Dereuddre-Bosquet; Mariangela Cavarelli; Anne-Sophie Gallouet; Pauline Maisonnasse; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | EVAg (653316), ANR | IDMIT (ANR-11-INBS-0008), EC | TRANSVAC2 (730964)

    Achieving sufficient worldwide vaccination coverage against SARS-CoV-2 will require additional approaches to currently approved viral vector and mRNA vaccines. Subunit vaccines may have distinct advantages when immunizing vulnerable individuals, children and pregnant wo...

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  • publication . Article . Other literature type . 2021
    Open Access English
    Authors:
    Marek Ostaszewski; Anna Niarakis; Alexander Mazein; Inna Kuperstein; Robert Phair; Aurelio Orta-Resendiz; Vidisha Singh; Sara Sadat Aghamiri; Marcio Luis Acencio; Enrico Glaab; ...
    Publisher: HAL CCSD
    Countries: Sweden, Spain, United Kingdom, Germany, France, Germany, Netherlands, United Kingdom, Luxembourg, France ...
    Project: EC | INFORE (825070), EC | PerMedCoE (951773), EC | iPLACENTA (765274)

    We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS-CoV-2 infection, improving data interpretation and predicting key targets of intervention. Here, we describe a large-scale community effort t...

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6 research outcomes, page 1 of 1