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  • Open Access English
    Authors: 
    Sabina Rinaldi; Martyn Plummer; Carine Biessy; Konstantinos K. Tsilidis; Jane Nautrup Østergaard; Kim Overvad; Anne Tjønneland; Jytte Halkjær; Marie-Christine Boutron-Ruault; Françoise Clavel-Chapelon; +35 more
    Countries: Denmark, United Kingdom

    BACKGROUND: Increased levels of thyroglobulin (Tg) and thyroid-stimulating hormone (TSH) are associated with differentiated thyroid carcinoma (TC) risk, but strong epidemiological evidence is lacking.METHODS: Three hundred fifty-seven incident TC case patients (n = 300 ...

  • Open Access English
    Authors: 
    Elizabeth Vafiadaki; Demetrios A. Arvanitis; Vasiliki Papalouka; Gerasimos Terzis; Theodoros I. Roumeliotis; Konstantinos Spengos; Spiros D. Garbis; Panagiota Manta; Evangelia G. Kranias; Despina Sanoudou;

    Muscle lim protein (MLP) has emerged as a critical regulator of striated muscle physiology and pathophysiology. Mutations in cysteine and glycine-rich protein 3 (CSRP3), the gene encoding MLP, have been directly associated with human cardiomyopathies, whereas aberrant e...

  • Publication . Other literature type . Article . 2020
    Open Access English
    Authors: 
    Bruce C. Trapnell; Yoshikazu Inoue; Francesco Bonella; Cliff Morgan; Stéphane Jouneau; Elisabeth Bendstrup; Ilaria Campo; Spyros Papiris; Etsuro Yamaguchi; Erdogan Cetinkaya; +10 more
    Publisher: HAL CCSD
    Countries: Denmark, France, France, Germany

    International audience; BACKGROUND: Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare disease characterized by progressive surfactant accumulation and hypoxemia. It is caused by disruption of granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling, ...

  • Open Access English
    Authors: 
    Dimitris K. Iakovidis; Melanie Ooi; Ye Chow Kuang; Serge Demidenko; Alexandr Shestakov; Vladimir Sinitsin; Manus Henry; Andrea Sciacchitano; Stefano Discetti; Silvano Donati; +24 more
    Publisher: IOP Publishing
    Countries: Italy, United Kingdom, Germany
    Project: EC | NEXTFLOW (949085)

    Signal processing is a fundamental component of almost any sensor-enabled system, with a wide range of applications across different scientific disciplines. Time series data, images, and video sequences comprise representative forms of signals that can be enhanced and a...

  • Open Access English
    Authors: 
    Aristeidis A. Nezis; Dionysios Angelidis; Vasiliki D. Assimakopoulos; G. Bergeles;
    Publisher: Croatian meteorological society
    Country: Croatia

    thermal behaviour of the materials, e.g., the street floor under the sun and on the geometrical characteristics of the surrounding buildings under low wind conditions. They have a detrimental effect on the stability conditions within and above street canyons, which in t...

  • Open Access English
    Authors: 
    Mattias Johansson; Anouar Fanidi; David C. Muller; Julie K. Bassett; Øivind Midttun; Stein Emil Vollset; Ruth C. Travis; Domenico Palli; Amalia Mattiello; Sabina Sieri; +32 more
    Publisher: Oxford University Press
    Countries: United States, Norway, United Kingdom, Norway, Sweden, Norway

    BACKGROUND: The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival.METHODS: The European Prospective Investigation into Cancer and ...

  • Open Access English
    Authors: 
    Tarsitsa Gatou; Haroula Koletsi Kounari; Eleni Mamai-Homata;
    Publisher: Elsevier

    Objectives: To investigate the association between certain socio-demographic characteristics and dental health status of 5- to 12-year-old children attending public kindergarten and primary schools in Piraeus, Greece. Methods: Gender, age, place of residence, immigrant ...

  • Open Access English
    Authors: 
    Elias Koulouridis; Bianca M. Poggianti; Bruno Altieri; Ivan Valtchanov; Yara L. Jaffé; C. Adami; Andrii Elyiv; O. Melnyk; Sotiria Fotopoulou; Fabio Gastaldello; +6 more
    Publisher: HAL CCSD
    Countries: Croatia, Belgium, Italy, France

    Context. This article belongs to the first series of XXL publications. It presents multifibre spectroscopic observations of three 0.55 deg2 fields in the XXL Survey, which were selected on the basis of their high density of X-ray-detected clusters. The observations were...

  • Open Access English
    Authors: 
    Montserrat Garcia-Closas; Fergus J. Couch; Kyriaki Michailidou; Marjanka K. Schmidt; Mark N. Brook; Nick Orr; Suhn K. Rhie; Elio Riboli; Heather Spencer Feigelson; Loic Le Marchand; +209 more
    Countries: United Kingdom, United Kingdom, Netherlands, Ireland
    Project: NIH | Characterizing Genetic Su... (5U01CA098233-06), NIH | Discovery Expansion and R... (5U19CA148065-04), NIH | Breast &prostate cancer &... (1U01CA098216-01), NIH | Genetic epidemiology of c... (3R01CA122340-03S1), EC | COGS (223175), NIH | Characterizing Genetic Su... (5U01CA098710-06), NIH | Breast &Prostate Cancer &... (1U01CA098758-01), WT , CIHR

    Estrogen receptor (ER)-negative tumors represent 20-30% of all breast cancers, with a higher proportion occurring in younger women and women of African ancestry. The etiology and clinical behavior of ER-negative tumors are different from those of tumors expressing ER (E...

  • Publication . Article . Other literature type . 2019 . Embargo End Date: 01 Jan 2019
    Open Access English
    Authors: 
    Ignacio Rubio; Marcin F. Osuchowski; Manu Shankar-Hari; Tomasz Skirecki; Martin Sebastian Winkler; Gunnar Lachmann; Paul La Rosée; Guillaume Monneret; Fabienne Venet; Michael Bauer; +20 more
    Publisher: Elsevier
    Countries: Netherlands, Italy, Germany

    Increasing evidence supports a central role of the immune system in sepsis, but the current view of how sepsis affects immunity, and vice versa, is still rudimentary. The European Group on Immunology of Sepsis has identified major gaps that should be addressed with high...