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- Publication . Book . 2012Open Access GermanAuthors:Georgi, Fabian;Georgi, Fabian;Publisher: Humboldt-Universität zu Berlin, Philosophische Fakultät III, Institut für SozialwissenschaftenCountry: Germany
In den vergangenen zehn Jahren hat sich in der internationalen Migrationspolitik ein neues Konzept etabliert: ‚Migrationsmanagement‘. ‚Migration muss gemanagt werden, um die Vorteile der Migration maximieren und ihre negativen Folgen minimieren‘ zu können, so lautet die utilitaristische Kernbotschaft. Ausgangspunkt dieses politischen Projekts war der ökonomische Globalisierungsschub nach der Weltwirtschaftskrise 1973. In seiner Folge verstärkte sich die internationale Mobilität von Menschen: Migration wurde zu einer offensiven und aus staatlicher Sicht potenziell unkontrollierbaren Strategie vieler Menschen, mit der sie auf die Folgen neoliberaler Reformen reagierten. Unter dem Etikett Migrationsmanagement propagierten Expert_innen aus dem Umfeld u. a. der International Organization for Migration (IOM) und des International Centre for Migration Policy Development (ICMPD) eine Gegenstrategie: Die staatlichen Fähigkeiten zur Begrenzung unerwünschter Migration sollen gesteigert werden, um eine ,regulierte Offenheit’ gegenüber ‚nützlicher‘ Zuwanderung beherrschbar zu machen. Politisch lässt sich das Projekt der liberalen Strömung in den internationalen Beziehungen zuordnen. Migration wird als positiv betrachtet, weil und insofern sie ökonomisch nützlich ist. So wird deutlich, dass das Projekt den Interessen wirtschaftlich und politischer dominierender Kräfte im Weltsystem eher nutzt, als der großen Mehrheit der Weltbevölkerung.
- Publication . Article . 1969Open AccessAuthors:S Golder; V Lopez; H Keller;S Golder; V Lopez; H Keller;Publisher: Kooperation de GruyterCountry: Germany
Peer Reviewed
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Book . 2016Open Access GermanAuthors:Talke, Armin;Talke, Armin;Publisher: Humboldt-Universität zu BerlinCountry: Germany
- Publication . Article . 2022Open AccessAuthors:Adrian Unc; Bartosz Adamczyk; Nils Borchard;Adrian Unc; Bartosz Adamczyk; Nils Borchard;Publisher: Frontiers Media SACountry: Germany
Peer Reviewed
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Book . 2019Open Access GermanAuthors:Canan, Coskun; Foroutan, Naika;Canan, Coskun; Foroutan, Naika;Publisher: Humboldt-Universität zu BerlinCountry: Germany
- Publication . Article . 2016Open Access GermanAuthors:Perler, Dominik;Perler, Dominik;
doi: 10.18452/21718
Publisher: Humboldt-Universität zu BerlinCountry: GermanyLeibniz holds that we cannot give an account of the synchronic and diachronic identity of a person without appealing to a substance. This paper analyses his reasons for this anti-Lockean thesis. It first looks at his theory of substance, paying particular attention to his commitment to the Principle of Sufficient Reason: the existence of a well-ordered series of mental states cannot be sufficiently explained without reference to a substance. The paper then examines the distinction Leibniz draws between the substance as the “real person” and the “appearing person” that comes into existence through reflexive consciousness. It argues that there can be no appearing person without a real person and looks at the relationship between these two types of person. Leibniz’s distinction is still relevant because it shows that questions concerning the metaphysical constitution of a person need to be carefully distinguished from questions concerning the psychological construction of a personality. Peer Reviewed
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Doctoral thesis . 2001Open Access GermanAuthors:Ilouga, Pierre Emmanuel;Ilouga, Pierre Emmanuel;
doi: 10.18452/14624
Publisher: Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät IICountry: GermanyDas Hauptanliegen dieser Arbeit ist der asymptotische Vergleich verschiedener nichtparametrischer adaptiver Schätzer des Mittelwertvektors in einer Regressionssituation mit wachsender Anzahl von Wiederholungen an festen Versuchspunkten. Da die adaptiven Schätzer nicht mehr linear in den Beobachtungen sind, wird ihre mittleren quadratischen Fehler durch ihre Risiken höherer Ordnung approximiert und dadurch wird ein Vergleich unter Annahme normalverteilter Beobachtungsfehlern ermöglicht. Es wird gezeigt, daß der Plug-In Schätzer des unbekannten Mittelwertvektors in dritter Ordnung besser ist als die anderen adaptiven Schätzer und, daß die mit Hilfe der Full Cross-validation Idee konstruierte Schätzer des Mittelwertvektors besser ist als die Schätzung mit Cross-validation, falls die unbekannte Regressionsfunktion "unglatt" ist. In speziellen Situationen ist die Full Cross-validation Adaptation besser als die Adaptationen mit Hilfe der in der Arbeit betrachteten "automatischen" Kriterien. Es wird außerdem einen Schätzer des Mittelwertvektors mit einer Plug-In Idee konstruiert, dessen Risiken zweiter Ordnung kleiner sind als die Risiken zweiter Ordnung der anderen adaptiven Schätzer. Wenn aber eine Vermutung vorliegt, daß die unbekannte Regressionsfunktion "sehr glatt" ist, wird bewiesen daß der Projektionsschätzer den kleinsten mittleren quadratischen Fehler liefert. The main objective of this thesis is the asymptotic comparison of various nonparametric adaptive estimators of the mean vector in a regression situation with increasing number of replications at fixed design points. Since the adaptive estimators are no longer linear in the observations, one approximates their mean square errors by their heigher order risks and a comparison under the assumption of normal distributed errors of the observations will be enabled. It is shown that the Plug-In estimators of the unknown mean vector is better in third order than the others adaptive estimators and that the estimator defined with the full cross-validation idea is better than the estimator with cross-validation, if the unknown regression function is "non smooth". In some special situations, the full cross-validation adaptation will be better than the adaptations using a minimizer of the "automatic" criteria considered in this thesis. Additionally, an estimator of the mean vector is proposed, whose second order risk is smaller than the second order risks of the other adaptive estimators. If however one presumes that the unknown regression function is "very smooth", then it is shown that the projection estimator gives the smallest mean square error.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Article . 1987Open AccessAuthors:Ellen Schmidt; F. W. Schmidt;Ellen Schmidt; F. W. Schmidt;Publisher: Kooperation de GruyterCountry: Germany
Peer Reviewed
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Book . 2006Open Access EnglishAuthors:Bartels, Sören; Carstensen, Carsten;Bartels, Sören; Carstensen, Carsten;Publisher: Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II, Institut für MathematikCountry: Germany
Abstract. The optimal design problem for maximal torsion stiffness of an infinite bar of given geometry and unknown distribution of two materials of prescribed amounts is one model example in topology optimisation. It eventually leads to a degenerated convex minimisation problem. The numerical analysis is therefore delicate for possibly multiple primal variables $u$ but unique derivatives $\sigma := DW(Du)$. Even sharp a posteriori error estimates still suffer from the reliability-efficiency gap. However, it motivates a simple edgebased adaptive mesh-refining algorithm (AFEM) that is not a priori guaranteed to refine everywhere. Its convergence proof is therefore based on energy estimates and some refined convexity control. Numerical experiments illustrate even nearly optimal convergence rates of the proposed adaptive finite element method (AFEM).
- Publication . Article . 2019Open Access EnglishAuthors:Hengge, Regine;Hengge, Regine;
pmc: PMC6650844
pmid: 31261858
Publisher: Humboldt-Universität zu BerlinCountry: GermanyBacterial biofilms are multicellular aggregates in which cells are embedded in an extracellular matrix of self-produced biopolymers. Being refractory to antibiotic treatment and host immune systems, biofilms are involved in most chronic infections, and anti-biofilm agents are being searched for urgently. Epigallocatechin-3-gallate (EGCG) was recently shown to act against biofilms by strongly interfering with the assembly of amyloid fibres and the production of phosphoethanolamin-modified cellulose fibrils. Mechanistically, this includes a direct inhibition of the fibre assembly, but also triggers a cell envelope stress response that down-regulates the synthesis of these widely occurring biofilm matrix polymers. Based on its anti-amyloidogenic properties, EGCG seems useful against biofilms involved in cariogenesis or chronic wound infection. However, EGCG seems inefficient against or may even sometimes promote biofilms which rely on other types of matrix polymers, suggesting that searching for ‘magic bullet’ anti-biofilm agents is an unrealistic goal. Combining molecular and ecophysiological aspects in this review also illustrates why plants control the formation of biofilms on their surfaces by producing anti-amyloidogenic compounds such as EGCG. These agents are not only helpful in combating certain biofilms in chronic infections but even seem effective against the toxic amyloids associated with neuropathological diseases. Deutsche Forschungsgemeinschaft Berliner Sparkassenstiftung Medizin Peer Reviewed
add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.
24,635 Research products, page 1 of 2,464
Loading
- Publication . Book . 2012Open Access GermanAuthors:Georgi, Fabian;Georgi, Fabian;Publisher: Humboldt-Universität zu Berlin, Philosophische Fakultät III, Institut für SozialwissenschaftenCountry: Germany
In den vergangenen zehn Jahren hat sich in der internationalen Migrationspolitik ein neues Konzept etabliert: ‚Migrationsmanagement‘. ‚Migration muss gemanagt werden, um die Vorteile der Migration maximieren und ihre negativen Folgen minimieren‘ zu können, so lautet die utilitaristische Kernbotschaft. Ausgangspunkt dieses politischen Projekts war der ökonomische Globalisierungsschub nach der Weltwirtschaftskrise 1973. In seiner Folge verstärkte sich die internationale Mobilität von Menschen: Migration wurde zu einer offensiven und aus staatlicher Sicht potenziell unkontrollierbaren Strategie vieler Menschen, mit der sie auf die Folgen neoliberaler Reformen reagierten. Unter dem Etikett Migrationsmanagement propagierten Expert_innen aus dem Umfeld u. a. der International Organization for Migration (IOM) und des International Centre for Migration Policy Development (ICMPD) eine Gegenstrategie: Die staatlichen Fähigkeiten zur Begrenzung unerwünschter Migration sollen gesteigert werden, um eine ,regulierte Offenheit’ gegenüber ‚nützlicher‘ Zuwanderung beherrschbar zu machen. Politisch lässt sich das Projekt der liberalen Strömung in den internationalen Beziehungen zuordnen. Migration wird als positiv betrachtet, weil und insofern sie ökonomisch nützlich ist. So wird deutlich, dass das Projekt den Interessen wirtschaftlich und politischer dominierender Kräfte im Weltsystem eher nutzt, als der großen Mehrheit der Weltbevölkerung.
- Publication . Article . 1969Open AccessAuthors:S Golder; V Lopez; H Keller;S Golder; V Lopez; H Keller;Publisher: Kooperation de GruyterCountry: Germany
Peer Reviewed
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Book . 2016Open Access GermanAuthors:Talke, Armin;Talke, Armin;Publisher: Humboldt-Universität zu BerlinCountry: Germany
- Publication . Article . 2022Open AccessAuthors:Adrian Unc; Bartosz Adamczyk; Nils Borchard;Adrian Unc; Bartosz Adamczyk; Nils Borchard;Publisher: Frontiers Media SACountry: Germany
Peer Reviewed
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Book . 2019Open Access GermanAuthors:Canan, Coskun; Foroutan, Naika;Canan, Coskun; Foroutan, Naika;Publisher: Humboldt-Universität zu BerlinCountry: Germany
- Publication . Article . 2016Open Access GermanAuthors:Perler, Dominik;Perler, Dominik;
doi: 10.18452/21718
Publisher: Humboldt-Universität zu BerlinCountry: GermanyLeibniz holds that we cannot give an account of the synchronic and diachronic identity of a person without appealing to a substance. This paper analyses his reasons for this anti-Lockean thesis. It first looks at his theory of substance, paying particular attention to his commitment to the Principle of Sufficient Reason: the existence of a well-ordered series of mental states cannot be sufficiently explained without reference to a substance. The paper then examines the distinction Leibniz draws between the substance as the “real person” and the “appearing person” that comes into existence through reflexive consciousness. It argues that there can be no appearing person without a real person and looks at the relationship between these two types of person. Leibniz’s distinction is still relevant because it shows that questions concerning the metaphysical constitution of a person need to be carefully distinguished from questions concerning the psychological construction of a personality. Peer Reviewed
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Doctoral thesis . 2001Open Access GermanAuthors:Ilouga, Pierre Emmanuel;Ilouga, Pierre Emmanuel;
doi: 10.18452/14624
Publisher: Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät IICountry: GermanyDas Hauptanliegen dieser Arbeit ist der asymptotische Vergleich verschiedener nichtparametrischer adaptiver Schätzer des Mittelwertvektors in einer Regressionssituation mit wachsender Anzahl von Wiederholungen an festen Versuchspunkten. Da die adaptiven Schätzer nicht mehr linear in den Beobachtungen sind, wird ihre mittleren quadratischen Fehler durch ihre Risiken höherer Ordnung approximiert und dadurch wird ein Vergleich unter Annahme normalverteilter Beobachtungsfehlern ermöglicht. Es wird gezeigt, daß der Plug-In Schätzer des unbekannten Mittelwertvektors in dritter Ordnung besser ist als die anderen adaptiven Schätzer und, daß die mit Hilfe der Full Cross-validation Idee konstruierte Schätzer des Mittelwertvektors besser ist als die Schätzung mit Cross-validation, falls die unbekannte Regressionsfunktion "unglatt" ist. In speziellen Situationen ist die Full Cross-validation Adaptation besser als die Adaptationen mit Hilfe der in der Arbeit betrachteten "automatischen" Kriterien. Es wird außerdem einen Schätzer des Mittelwertvektors mit einer Plug-In Idee konstruiert, dessen Risiken zweiter Ordnung kleiner sind als die Risiken zweiter Ordnung der anderen adaptiven Schätzer. Wenn aber eine Vermutung vorliegt, daß die unbekannte Regressionsfunktion "sehr glatt" ist, wird bewiesen daß der Projektionsschätzer den kleinsten mittleren quadratischen Fehler liefert. The main objective of this thesis is the asymptotic comparison of various nonparametric adaptive estimators of the mean vector in a regression situation with increasing number of replications at fixed design points. Since the adaptive estimators are no longer linear in the observations, one approximates their mean square errors by their heigher order risks and a comparison under the assumption of normal distributed errors of the observations will be enabled. It is shown that the Plug-In estimators of the unknown mean vector is better in third order than the others adaptive estimators and that the estimator defined with the full cross-validation idea is better than the estimator with cross-validation, if the unknown regression function is "non smooth". In some special situations, the full cross-validation adaptation will be better than the adaptations using a minimizer of the "automatic" criteria considered in this thesis. Additionally, an estimator of the mean vector is proposed, whose second order risk is smaller than the second order risks of the other adaptive estimators. If however one presumes that the unknown regression function is "very smooth", then it is shown that the projection estimator gives the smallest mean square error.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Article . 1987Open AccessAuthors:Ellen Schmidt; F. W. Schmidt;Ellen Schmidt; F. W. Schmidt;Publisher: Kooperation de GruyterCountry: Germany
Peer Reviewed
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Book . 2006Open Access EnglishAuthors:Bartels, Sören; Carstensen, Carsten;Bartels, Sören; Carstensen, Carsten;Publisher: Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II, Institut für MathematikCountry: Germany
Abstract. The optimal design problem for maximal torsion stiffness of an infinite bar of given geometry and unknown distribution of two materials of prescribed amounts is one model example in topology optimisation. It eventually leads to a degenerated convex minimisation problem. The numerical analysis is therefore delicate for possibly multiple primal variables $u$ but unique derivatives $\sigma := DW(Du)$. Even sharp a posteriori error estimates still suffer from the reliability-efficiency gap. However, it motivates a simple edgebased adaptive mesh-refining algorithm (AFEM) that is not a priori guaranteed to refine everywhere. Its convergence proof is therefore based on energy estimates and some refined convexity control. Numerical experiments illustrate even nearly optimal convergence rates of the proposed adaptive finite element method (AFEM).
- Publication . Article . 2019Open Access EnglishAuthors:Hengge, Regine;Hengge, Regine;
pmc: PMC6650844
pmid: 31261858
Publisher: Humboldt-Universität zu BerlinCountry: GermanyBacterial biofilms are multicellular aggregates in which cells are embedded in an extracellular matrix of self-produced biopolymers. Being refractory to antibiotic treatment and host immune systems, biofilms are involved in most chronic infections, and anti-biofilm agents are being searched for urgently. Epigallocatechin-3-gallate (EGCG) was recently shown to act against biofilms by strongly interfering with the assembly of amyloid fibres and the production of phosphoethanolamin-modified cellulose fibrils. Mechanistically, this includes a direct inhibition of the fibre assembly, but also triggers a cell envelope stress response that down-regulates the synthesis of these widely occurring biofilm matrix polymers. Based on its anti-amyloidogenic properties, EGCG seems useful against biofilms involved in cariogenesis or chronic wound infection. However, EGCG seems inefficient against or may even sometimes promote biofilms which rely on other types of matrix polymers, suggesting that searching for ‘magic bullet’ anti-biofilm agents is an unrealistic goal. Combining molecular and ecophysiological aspects in this review also illustrates why plants control the formation of biofilms on their surfaces by producing anti-amyloidogenic compounds such as EGCG. These agents are not only helpful in combating certain biofilms in chronic infections but even seem effective against the toxic amyloids associated with neuropathological diseases. Deutsche Forschungsgemeinschaft Berliner Sparkassenstiftung Medizin Peer Reviewed
add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.