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  • Open Access English
    Authors: 
    Clara Strauss; Charlotte Dunkeld; Kate Cavanagh;
    Publisher: Elsevier
    Country: United Kingdom

    Depression is the leading cause of disability globally and has serious consequences for the individual, their family and for society. Effective, accessible and affordable treatments are urgently needed. In-person group-based mindfulness-based interventions are an effect...

  • Open Access English
    Authors: 
    Albertyna Paciorek; Lina Skora; Lina Skora;
    Publisher: Frontiers Media S.A.
    Country: United Kingdom
    Project: EC | TRAINCREASE (952324)

    The last two decades have seen a growing interest in the study of interoception. Interoception can be understood as a hierarchical phenomenon, referring to the body-to-brain communication of internal signals, their sensing, encoding, and representation in the brain, inf...

  • Open Access English
    Authors: 
    Towler, Benjamin P; Jones, Christopher I; Viegas, Sandra C; Apura, Patricia; Waldron, Joseph A; Smalley, Sarah K; Arraiano, Cecilia M; Newbury, Sarah F;
    Publisher: Landes Bioscience
    Country: United Kingdom
    Project: EC | ST-FLOW (289326), UKRI | Function of the exoribonu... (BB/G002754/1), UKRI | Epigenetic regulation of ... (BB/I021345/1), FCT | EXPL/BEX-BCM/1317/2013 (EXPL/BEX-BCM/1317/2013)

    Dis3 is a highly conserved exoribonuclease which degrades RNAs in the 3'-5' direction. Mutations in Dis3 are associated with a number of human cancers including multiple myeloma and acute myeloid leukaemia. In this work, we have assessed the effect of a Dis3 knockdown o...

  • Open Access English
    Authors: 
    Abraham, N L; Allbrooke, B M M; Asquith, L; Cerri, A; Chavez Barajas, C; De Santo, A; Jones, S D; Lerner, G; Miano, F; Santoyo Castillo, I; +12 more
    Publisher: Elsevier
    Country: United Kingdom

    Searches for the exclusive decays of the Higgs and Z bosons into a J/ψ,ψ(2S), or Υ(nS)(n=1,2,3) meson and a photon are performed with a pp collision data sample corresponding to an integrated luminosity of 36.1 fb −1 collected at √s =13 TeV with the ATLAS detector at th...

  • Open Access English
    Authors: 
    Meisenberg, Cornelia; Pinder, Sarah I; Hopkins, Suzanna R; Wooller, Sarah K; Benstead-Hume, Graeme; Pearl, Frances M G; Jeggo, Penny A; Downs, Jessica A;
    Publisher: Cell Press
    Country: United Kingdom
    Project: UKRI | Mechanistic analysis of D... (MR/N02155X/1)

    Summary Cohesin subunits are frequently mutated in cancer, but how they function as tumor suppressors is unknown. Cohesin mediates sister chromatid cohesion, but this is not always perturbed in cancer cells. Here, we identify a previously unknown role for cohesin. We fi...

  • Open Access English
    Authors: 
    Marcella Brusa; Chiara Feruglio; Giovanni Cresci; V. Mainieri; Mark Sargent; Michele Perna; Paola Santini; Fabio Vito; Alessandro Marconi; Andrea Merloni; +9 more
    Publisher: HAL CCSD
    Countries: France, United Kingdom, Italy, Italy
    Project: EC | EEASY (321913)

    Gas outflows are believed to play a pivotal role in shaping galaxies, as they regulate both star formation and black hole growth. Despite their ubiquitous presence, the origin and the acceleration mechanism of such powerful and extended winds is not yet understood. Dire...

  • Open Access English
    Authors: 
    Julian Gregory; Benjamin K. Sovacool;
    Countries: United Kingdom, Denmark

    The recent academic literature contains a number of hypotheses, drivers, or explanations to reveal why electricity infrastructure isn't being developed within sub-Saharan Africa (SSA) in the 21st century. In this paper, we argue that this literature is misdirected, or a...

  • Open Access English
    Authors: 
    Tracy Epton; Paul Norman; Peter R. Harris; Thomas L. Webb; F Alexandra Snowsill; Paschal Sheeran;
    Publisher: Oxford University Press
    Country: United Kingdom
    Project: WT

    Online health behaviour interventions have great potential but their effectiveness may be hindered by a lack of formative and theoretical work. This paper describes the process of formative research to develop theoretically and empirically based health messages that are...

  • Open Access English
    Authors: 
    Fazi, M Beatrice;
    Publisher: Computational Culture
    Country: United Kingdom

    In 1931, Kurt Gödel determined the incompleteness of formal axiomatic systems by demonstrating that there are propositions that cannot be proved or disproved within the system in question. In 1936, Alan Turing showed that some functions cannot be computed, and thereby d...

  • Open Access English
    Authors: 
    Emily Baron; Sujit D Rathod; Charlotte Hanlon; Martin Prince; Abebaw Fedaku; Fred Kigozi; Mark J. D. Jordans; Nagendra P. Luitel; Girmay Medhin; Vaibhav Murhar; +9 more
    Countries: United Kingdom, Netherlands, United States, South Africa
    Project: NWO | New Detector Systems for ... (2300168457), WT

    Abstract Background The Programme for Improving Mental Health Care (PRIME) sought to implement mental health care plans (MHCP) for four priority mental disorders (depression, alcohol use disorder, psychosis and epilepsy) into routine primary care in five low- and middl...